Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Award Type [Axis] Award Type [Axis] Equity Award [Domain] Equity Award [Domain] Stock-based Compensation Employee And Non Employee Stock Option Excluding Bonus Compensation [Member] An arrangement whereby an employee or non-employee is entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement, excluding options granted as bonus related compensation. Stock-based Compensation, employees Employee Stock Option Excluding Bonus Compensation [Member] An arrangement whereby an employee is entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement, excluding options granted as bonus compensation. Stock-based Compensation, non-employees Non Employee Stock Option [Member] An arrangement whereby a non-employee is entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement. ESPP Employee Stock [Member] Stock incentive plans Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Summary of activity under the Company's stock option plans Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of share-based compensation expense Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of assumptions used to calculate estimated grant date fair value of stock options using the Black-Scholes option-pricing valuation model Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Earnings Per Share [Abstract] Calculation of basic and diluted net loss per common share Earnings Per Share, Basic and Diluted [Abstract] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Options Employee And Non Employee Stock Option [Member] An arrangement whereby an employee or non-employee is entitled to receive in the future, subject to vesting and other restrictions, number of shares in the entity at a specified price, as defined in the agreement. Employee stock purchase plan Equity Unit Purchase Agreements [Member] Restricted stock units (RSUs) Restricted Stock Units (RSUs) [Member] Outstanding shares of common stock equivalents that have been excluded from diluted net loss per common share Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Shares of common stock subject to outstanding options Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Equity [Abstract] Schedule of reserved shares of common stock for issuance Schedule of Common Stock Capital Shares Reserved for Future Issuance [Table Text Block] Tabular disclosure of number of common shares reserved for future issuance. Business Combinations [Abstract] Business Combination Business Combination Disclosure [Text Block] Statement of Stockholders' Equity [Abstract] Statement [Table] Statement [Table] Equity Components [Axis] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock Common Stock [Member] Additional Paid-in Capital Additional Paid-in Capital [Member] Accumulated Deficit Retained Earnings [Member] Statement Statement [Line Items] Increase (Decrease) in Convertible Preferred Stock and Stockholders' Equity (Deficit) Increase (Decrease) in Convertible Preferred Stock and Stockholders Equity [Roll Forward] A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period. Balance Stockholders' Equity Attributable to Parent Balance (in shares) Shares, Outstanding Issuance of common stock on exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Issuance of common stock on exercise of stock options (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Issuance of common stock under employee stock purchase plan (ESPP) Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of common stock on employee stock purchase plan (ESPP) (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of common stock on cashless exercise of warrant (in shares) Stock Issued During Period Shares Warrants Exercised Number of shares of stock issued during the period as a result of the exercise of warrants. Common stock subject to repurchase Adjustments to Additional Paid in Capital Common Stock Subject to Repurchase Represents the amount of increase (decrease) in additional paid-in capital (APIC) due to common stock subject to repurchase. Issuance of common stock for acquisition Stock Issued During Period, Value, Acquisitions Issuance of common stock for acquisition (in shares) Stock Issued During Period, Shares, Acquisitions Sale of common stock in a private placement, net of issuance costs Stock Issued And Sold During Period Value In Private Placement Value of shares issued and sold during the period in a private placement. Sale of common stock in a private placement, net of issuance costs (in shares) Stock Issued And Sold During Period, Shares, In Private Placement Number of shares issued and sold during the period in a private placement. Issuance of common stock in a private placement, issuance cost Common Stock Issued Issuance Costs Private Placement Represents issuance costs pertaining to the sale of common stock in a private placement. Stock-based compensation expense (employee) Adjustments to Additional Paid in Capital Share Based Compensation Employee Amount of increase in additional paid-in capital (APIC) resulting from employee stock-based compensation expense. Stock-based compensation expense (non-employee) Adjustments to Additional Paid in Capital Share Based Compensation Non Employee Amount of increase in additional paid-in capital (APIC) resulting from non-employee stock-based compensation expense. Stock-based compensation expense (ESPP) Adjustments To Additional Paid In Capital Share Based Compensation ESPP Amount of increase in additional paid-in capital (APIC) resulting from ESPP stock-based compensation expense. Net loss Net Income (Loss) Available to Common Stockholders, Basic Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Balance Balance (in shares) Schedule of Business Acquisitions, by Acquisition [Table] Schedule of Business Acquisitions, by Acquisition [Table] Business Acquisition [Axis] Business Acquisition [Axis] Business Acquisition, Acquiree [Domain] Business Acquisition, Acquiree [Domain] Allegro Allegro Diagnostics Corp [Member] Represents Allegro Diagnostics Corp., an acquiree of the entity. Business Combination Business Acquisition [Line Items] Schedule of acquisition consideration Schedule of Components of Acquisition Consideration [Table Text Block] Tabular disclosure of components of acquisition consideration. Schedule of fair value of assets acquired and liabilities assumed Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block] Schedule of pro forma financial information as if the Merger had occurred as of January 1, 2013 Business Acquisition, Pro Forma Information [Table Text Block] Commitments and Contingencies Disclosure [Abstract] Schedule of future minimum lease payments under non-cancelable operating leases Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] Thyroid Cytopathology Partners Schedule of Variable Interest Entities [Table] Schedule of Variable Interest Entities [Table] Variable Interest Entities [Axis] Variable Interest Entities [Axis] Variable Interest Entity, Classification [Domain] Variable Interest Entity, Classification [Domain] Thyroid Cytopathology Partners Variable Interest Entity, Not Primary Beneficiary [Member] Thyroid Cytopathology Partners Variable Interest Entity [Line Items] Notice of intent not to renew period Agreement Terms, Non-Renewal Notice Period Represents the minimum period required to provide notice of intent not to renew agreement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Expenses for cytopathology testing and evaluation services Testing and Evaluation Services Expense Testing and evaluation service costs directly related to generating revenues. Outstanding obligations Accounts Payable, Current Reduction to rent expense for TCP's portion of costs for shared space Other Income Rent Reimbursement Amount of reimbursement from third party for rent and related operating expenses for shared space included in other income in the income statement. Balance Sheet Related Disclosures [Abstract] Balance Sheet Components Supplemental Balance Sheet Disclosures [Text Block] Stockholders' Equity (Deficit) Stockholders' Equity Note Disclosure [Text Block] Quarterly Financial Information Disclosure [Abstract] Schedule of selected quarterly financial data (unaudited) Quarterly Financial Information [Table Text Block] Accounting Policies [Abstract] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Schedule of Stock by Class [Table] Schedule of Stock by Class [Table] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Prepaid Expenses and Other Current Assets Prepaid Expenses and Other Current Assets [Member] Sale of Stock [Axis] Sale of Stock [Axis] Sale of Stock [Domain] Sale of Stock [Domain] Private placement Private Placement [Member] Range [Axis] Range [Axis] Range [Domain] Range [Domain] Minimum Minimum [Member] Maximum Maximum [Member] Class of Stock [Line Items] Class of Stock [Line Items] Common Stock Common Stock [Abstract] No definition available. Authorized shares of common stock Common Stock, Shares Authorized Par value of shares of common stock (in dollars per share) Common Stock, Par or Stated Value Per Share Number of votes for each share of stock Voting Rights for Each Share of Stock Represents the number of votes for each share of stock. Dividends declared Dividends Payable Options issued and outstanding (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Shares available for issuance Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Total number of shares reserved for issuance Common Stock, Capital Shares Reserved for Future Issuance Common stock, shares issued Common Stock, Shares, Issued Shares issued, price per share (in usd per share) Shares Issued, Price Per Share Sale of stock, consideration received on transaction, gross Sale of Stock, Consideration Received on Transaction, Gross Sale of Stock, Consideration Received on Transaction, Gross Proceeds from issuance of common stock Sale of Stock, Consideration Received on Transaction Payments of stock issuance costs Payments of Stock Issuance Costs Accounts receivable Accounts Receivable, Gross Stock compensation expense Allocated Share-based Compensation Expense Number of common stock issued and sold in private placement Share Price (in usd per share) Share Price Gross proceeds from sale of common stock in private placement Proceeds from Issuance of Private Placement, Gross The gross proceeds received from the entity's raising of capital via private rather than public placement. Net proceeds from sale of common stock in private placement Proceeds from Issuance of Private Placement Agent fees and other expenses Placement Agent Fees And Other Expenses Represents the amount of agent fees and other expenses payable by the entity for private placement. Employee Stock Purchase Plan Employee Stock Purchase Plan [Abstract] No definition available. Maximum offering period Share-based Compensation Arrangement by Share-based Payment Award, Offering Period, Maximum The maximum offering period under the plan, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Minimum purchase price as a percentage of fair market value Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent Purchase period Share-based Compensation Arrangement by Share-based Payment Award, Purchase Period The purchase period under the plan, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Maximum fair market value of shares an employee can purchase per calendar year Share-based Compensation Arrangement by Share-based Payment Award, Maximum Value of Shares Per Employee The maximum fair market value of shares an employee can purchase under the plan per calendar year. Assumptions used to calculate estimated fair value of stock options using the Black-Scholes option-pricing valuation model Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Weighted-average volatility, low end of range (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Weighted-average volatility, high end of range (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Weighted-average expected term Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Risk-free interest rate, low end of range (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk-free interest rate, high end of range (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Employee stock options Employee Stock Option [Member] Shares Available for Grant Share Based Compensation Arrangement by Share Based Payment Award Number of Shares Available for Grant [Roll Forward] Balance at the beginning of the period (in shares) Additional options authorized (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Canceled (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Balance at the end of the period (in shares) Stock Options Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Balance at beginning of the period (in shares) Granted (in shares) Canceled (in shares) Exercised (in shares) Balance at the end of the period (in shares) Options vested and exercisable at the end of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Options vested and expected to vest at the end of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Weighted Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Balance at beginning of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Canceled (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Balance at the end of the period (in dollars per share) Options vested and exercisable at the end of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Options vested and expected to vest at the end of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Weighted Average Remaining Contractual Life Share Based Compensation Arrangement by Share Based Payment Award Options Weighted Average Remaining Contractual Life [Abstract] Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Options vested and exercisable at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Options vested and expected to vest at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Aggregate Intrinsic Value Share Based Compensation Arrangement by Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] Balance at the beginning of the period (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Balance at the end of the period (in dollars) Options vested and exercisable at the end of the period (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Options vested and expected to vest at the end of the period (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Additional disclosures Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract] Estimated fair value common stock (in dollars per share) Income Tax Disclosure [Abstract] Income Tax Examination [Table] Income Tax Examination [Table] Income Tax Authority [Axis] Income Tax Authority [Axis] Income Tax Authority [Domain] Income Tax Authority [Domain] Federal Domestic Tax Authority [Member] State State and Local Jurisdiction [Member] Income tax examination Income Tax Examination [Line Items] Income tax examination period Income Tax Examination Period Period which will remain open for examination by tax authorities, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Thyroid Cytopathology Partners Long-term Contracts or Programs Disclosure [Text Block] Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization and Description of Business Business Description and Basis of Presentation [Text Block] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Plan Name [Axis] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] 2008 Plan Stock Plan2008 [Member] Represents information pertaining to the 2008 Stock Plan (the 2008 Plan). ISO Incentive Stock Options [Member] Represents information pertaining to incentive stock options (ISOs). Cost of revenue Cost of Sales [Member] Research and development Research and Development Expense [Member] Selling and marketing Selling and Marketing Expense [Member] General and administrative General and Administrative Expense [Member] Stock-based compensation Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Term of options granted to a person owning stock representing more than 10% of voting power of all classes of stock Share Based Compensation Arrangement by Share Based Payment Award Term of Options Granted to Employees Who Owned Specified Percentage of Class of Stock Represents the term of options granted to persons owning stock representing specified percentage of voting power of all classes of stock, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Term of options granted Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period Share-based compensation expense (in dollars) Unrecognized compensation expense (in dollars) Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options Period over which unrecognized compensation expense expected to be recognized Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Concentration Risk [Table] Concentration Risk [Table] Concentration Risk Type [Axis] Concentration Risk Type [Axis] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Revenue concentration risk Customer Concentration Risk [Member] Gross receivables concentration risk Credit Concentration Risk [Member] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Revenue Sales Revenue Gross [Member] Revenue from sale of goods and services rendered, in the normal course of business, before deducting sales returns and allowances, and sales discounts, when it serves as a benchmark in a concentration of risk calculation. Accounts receivable Accounts Receivable [Member] Concentration Risk Concentration Risk [Line Items] Schedule of the Company's third-party payers as a percentage of total Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Revenue Recognition Revenue Recognition [Abstract] Schedule of Revenue recognized when cash is received and on an accrual basis Schedule of Revenue Recognition, Cash and Accrual Basis [Table Text Block] Tabular disclosure of recognition of revenue when cash is received and on an accrual basis. Statement of Cash Flows [Abstract] Operating activities Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Depreciation and amortization Depreciation, Depletion and Amortization Bad debt expense Provision for Doubtful Accounts Loss on disposal of property and equipment Gain (Loss) on Disposition of Property Plant Equipment Genzyme co-promotion fee amortization Recognition of Deferred Revenue Stock-based compensation Share-based Compensation Conversion of accrued interest to long-term debt Paid-in-Kind Interest Amortization of debt discount and issuance costs Amortization of Debt Issuance Costs and Discounts Interest on debt balloon payment and prepayment penalty Debt instrument end of term payment interest amount Represents the amount of interest end of term payment of debt. Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Accounts receivable Increase (Decrease) in Accounts Receivable Supplies inventory Increase (Decrease) in Inventories Prepaid expenses and current other assets Increase (Decrease) in Prepaid Expense and Other Assets Other assets Increase (Decrease) in Other Noncurrent Assets Accounts payable Increase (Decrease) in Accounts Payable Accrued liabilities and deferred rent Increase (Decrease) in Accrued Liabilities and Deferred Rent The increase (decrease) during the reporting period in the amount of expenses incurred but not yet paid and deferred rent. Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities, Continuing Operations Investing activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Cash remitted for acquisition, net of cash received Payments to Acquire Businesses, Net of Cash Acquired Change in restricted cash Increase (Decrease) in Restricted Cash Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations Financing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Proceeds from the issuance of long-term debt, net of debt issuance costs Proceeds from Issuance of Long-term Debt Proceeds from issuance of common stock in a private placement, net of issuance costs Proceeds from issuance of common stock in a public offering, net of issuance costs Proceeds from Issuance Initial Public Offering Commissions and issuance costs relating to initial public offering Payments of Stock Issuance Costs, Initial Public Offering The cash outflow for cost incurred directly with the issuance of an equity security in an initial public offering. Payment of long-term debt Repayments of Long-term Debt Payment of end-of-term debt obligation and prepayment penalty Payment of End of Term Obligation The cash outflow for the payment of the end-of-term obligation and prepayment penalty. Payment of deferred stock offering costs Payments of Stock Issuance Costs, Deferred Stock Offering Costs The cash outflow of deferred stock offering costs incurred directly with the issuance of an equity security. Proceeds from the exercise of common stock options and employee stock purchases Proceeds from Stock Options Exercised Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net increase (decrease) in cash and cash equivalents Net Cash Provided by (Used in) Continuing Operations Cash and cash equivalents at beginning of period Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents at end of period Supplementary cash flow information of non-cash investing and financing activities: Noncash Investing and Financing Items [Abstract] Fair value of common stock issued for acquisition Non-cash issuance of long-term debt Notes Issued Non-cash repayment of long-term debt Notes Reduction Net receivable for reimbursement of public offering issuance costs Reimbursement of Offering Costs Reimbursement of Offering Costs Purchases of property and equipment included in accounts payable and accrued liabilities Capital Expenditures Incurred but Not yet Paid Issuance of common stock from the non-cash exercise of common stock warrants Stock Issued, Exercise of Common Stock Warrants The fair value of stock issued in noncash exercise of common stock warrants. Supplementary cash flow information: Supplemental Cash Flow Information [Abstract] Cash paid for interest on debt Interest Paid Cash paid for tax Income Taxes Paid Schedule of outstanding shares of common stock equivalents that have been excluded from diluted net loss per common share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Income Taxes Income Tax Disclosure [Text Block] Accrued Liabilities Accrued Liabilities, Current [Abstract] Accrued compensation expenses Employee-related Liabilities, Current Accrued Genzyme co-promotion fees Accrued Marketing Costs, Current Accrued other Other Accrued Liabilities, Current Total accrued liabilities Accrued Liabilities, Current Pretax loss Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Provision for income taxes Income Tax Expense (Benefit) Reconciliation of tax expense computed at the statutory federal rate and the Company's tax expense Effective Income Tax Rate Reconciliation, Amount [Abstract] U.S. federal taxes at statutory rate Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount State tax (net of federal benefit) Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount Permanent differences Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount Incentive stock options Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-based Compensation Cost, Amount Tax credits Effective Income Tax Rate Reconciliation, Tax Credit, Amount Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Total provision for income taxes Tax effects of temporary differences and carryforwards that give rise to significant portions of the deferred tax assets Components of Deferred Tax Assets and Liabilities [Abstract] Non-current deferred tax assets: Components of Deferred Tax Assets Non Current [Abstract] Net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Research and development credits Deferred Tax Assets Tax Credit Carryforwards Research and Development Represents the amount before allocation of valuation allowances of deferred tax asset attributable to deductible research and development tax credit carryforwards. Stock-based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-based Compensation Cost Genzyme co-promotion agreement Deferred Tax Assets Deferred Income Non Current Represents the amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from non-current deferred income. Accruals, deferred rent and other Deferred Tax Assets Accruals, Deferred Rent and Other Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from non-current accruals, deferred rent and other reserves and accruals not separately disclosed. Gross deferred tax assets Deferred Tax Assets, Gross, Noncurrent Valuation allowance Deferred Tax Assets, Valuation Allowance, Noncurrent Net deferred tax assets Deferred Tax Assets, Net of Valuation Allowance, Noncurrent Deferred tax liabilities: Components of Deferred Tax Liabilities Non Current [Abstract] Property and equipment Deferred Tax Liabilities, Property, Plant and Equipment In-process research and development Deferred Tax Liabilities, Deferred Expense, Capitalized Research and Development Costs Gross deferred tax liabilities Deferred Tax Liabilities, Gross, Noncurrent Net deferred tax liabilities Deferred Tax Liabilities, Net Increase in valuation allowance against deferred tax assets Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Operating Loss Carryforwards [Table] Operating Loss Carryforwards [Table] Operating loss carryforwards Operating Loss Carryforwards [Line Items] Net operating loss carryforwards Operating Loss Carryforwards Federal and state net operating loss carryforwards related to stock-based compensation Operating Loss Carryforwards, Stock-Based Compensation Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws related to stock-based compensation. Selected Quarterly Financial Data (Unaudited) Quarterly Financial Information [Text Block] Debt Disclosure [Abstract] Schedule of Long-term Debt Instruments [Table] Schedule of Long-term Debt Instruments [Table] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Convertible Preferred Stock Warrants Convertible Preferred Stock Warrants [Member] Represents the security that gives the holder the right to purchase shares of convertible preferred stock in accordance with the terms of the instrument, usually upon payment of a specified amount. Long-term Debt, Type [Axis] Long-term Debt, Type [Axis] Long-term Debt, Type [Domain] Long-term Debt, Type [Domain] Term Loan Term Loan [Member] Represents the term loans under the loan and security agreement. Debt Instrument [Line Items] Debt Instrument [Line Items] Long-term debt and accrued end of term payment Long-term Debt and Accrued End Of Term Payment Amount of long-term debt before deduction of unamortized discount or premium and amount of unpaid accrued end of term payment. Debt instrument, unamortized discount Debt Instrument, Unamortized Discount Long-term debt Long-term Debt Impairment of intangible assets, indefinite-lived (excluding goodwill) Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill) Finite-lived Intangible Assets Finite-Lived Intangible Assets, Gross [Abstract] Useful life Finite-Lived Intangible Asset, Useful Life Finite-lived intangible assets, impairment Impairment of Intangible Assets, Finite-lived Goodwill Goodwill, Impaired [Abstract] Goodwill impairment Goodwill, Impairment Loss Schedule of Accounts, Notes, Loans and Financing Receivable [Table] Schedule of Accounts, Notes, Loans and Financing Receivable [Table] Receivable Type [Axis] Receivable Type [Axis] Receivable [Domain] Receivable [Domain] Accrued Income Receivable Accrued Income Receivable [Member] Accounts, Notes, Loans and Financing Receivable [Line Items] Accounts, Notes, Loans and Financing Receivable [Line Items] Property, plant and equipment, useful life (in years) Property, Plant and Equipment, Useful Life Revenue recognized on an accrual basis Revenue Recognized On Accrual Basis Revenue recognized during the period on an accrual basis. Revenue recognized on accrual basis, percentage Revenue Recognized On Accrual Basis, Percentage Revenue Recognized On Accrual Basis, Percentage Revenue recognized on a cash basis Revenue Recognized Received In Cash Revenue recognized during the period based on cash receipts. Revenue recognized on a cash basis, percentage Revenue Recognized Received In Cash, Percentage Revenue Recognized Received In Cash, Percentage Total Revenue, Net Total, Percent Revenue, Percent Revenue, Percent Net loss per common share, basic and diluted (in dollars per share) Earnings Per Share, Basic and Diluted Income Statement [Abstract] Revenue Operating Expenses: Operating Expenses [Abstract] Cost of revenue Cost of Revenue Research and development Research and Development Expense Selling and marketing Selling and Marketing Expense General and administrative General and Administrative Expense Intangible asset amortization Amortization of Intangible Assets Total operating expenses Operating Expenses Loss from operations Operating Income (Loss) Interest expense Interest Expense Other income, net Other Nonoperating Income (Expense) Net loss Comprehensive loss Shares use to compute net loss per common share, basic and diluted (in shares) Weighted Average Number of Shares Outstanding, Basic and Diluted Lender Name [Axis] Lender Name [Axis] Line of Credit Facility, Lender [Domain] Line of Credit Facility, Lender [Domain] Visium Visium [Member] Represents information pertaining to Visium Healthcare Partners, LP Line of Credit Line of Credit [Member] Debt Instrument [Axis] Debt Instrument [Axis] Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Initial Term Loan Initial Term Loan [Member] Represents the initial term loan. Second Term Loan Second Term Loan [Member] Represents the second term loan. Number of term loans Number Of Term Loans Represents the number of term loans available to the Company. Line of credit facility, maximum borrowing capacity Line of Credit Facility, Maximum Borrowing Capacity Proceeds from lines of credit Proceeds from Lines of Credit Repayments of long-term debt Interest rate, stated percentage Debt Instrument, Interest Rate, Stated Percentage Number of installments Debt Instrument Number of Installments Represents the number of installments for payment of the debt. Term of debt with equal quarterly installments Term Of Debt With Equal Quarterly Installments Represents the term of debt with equal quarterly installments. Fixed rate percentage paid in cash Debt Instrument Fixed Rate Percentage Paid In Cash Rate for which Company may elect to pay interest in cash. Interest paid-in-kind percentage Debt Instrument Interest Paid-In-Kind Percentage Percentage of interest rate for which interest is paid-in-kind by adding paid-in-kind interest to the outstanding principal amounts of the Term Loans. Minimum prepayment allowed Debt Instrument Minimum Prepayment Allowed Amount of prepayment allowed under the current agreement. Prepayment amount excess multiple Debt Instrument Prepayment Amount Excess Multiple The whole multiple for which payments must be made in excess of minimum prepayment. Penalty percentage on prepayment period one Debt Instrument Penalty Percentage On Prepayment Period One Represents the percentage of prepayment premium for prepayment made on or prior to March 31, 2018. Penalty percentage on prepayment period two Debt Instrument Penalty Percentage On Prepayment Period Two Represents the percentage of prepayment premium for prepayment after March 31, 2018 and on or prior to March 31, 2019. Penalty percentage on prepayment period three Debt Instrument Penalty Percentage On Prepayment Period Three Represents the percentage of prepayment premium for prepayment after March 31, 2019 and on or prior to March 31, 2020. Penalty percentage on prepayment period four Debt Instrument Penalty Percentage On Prepayment Period Four Represents the percentage of prepayment premium for prepayment after March 31, 2020 and on or prior to March 31, 2021. Period for which rights equity financings Debt Instrument Period For Which Rights Equity Financings The period for which the lender has the right to participate in certain future equity financings of the Company. Future equity financings amount Debt Instrument Future Equity Financings Amount The amount for which lender can participate in future equity financings. Genzyme Co-promotion Agreement Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Type of Arrangement and Non-arrangement Transactions [Axis] Type of Arrangement and Non-arrangement Transactions [Axis] Arrangements and Non-arrangement Transactions [Domain] Arrangements and Non-arrangement Transactions [Domain] Co-promotion agreement Collaborative Arrangement, Co-promotion [Member] Afirma thyroid diagnostic solution co-promotion agreement Collaborative Arrangement Copromotion Afirma Thyroid Diagnostic Solution [Member] Contractual arrangement involving the promotion the Company's Afirma thyroid diagnostic solution in which both the entity and its partner: (i) actively participate in the joint operating activity and (ii) are exposed to significant risks and rewards that depend on the commercial success of the joint operating activity. Ex-U.S. Co-Promotion Agreement Collaborative Arrangement Copromotion Afirma Gec [Member] Contractual arrangement involving the promotion of Afirma GEC in countries other than the United States in which both the entity and its partner: (i) actively participate in the joint operating activity and (ii) are exposed to significant risks and rewards that depend on the commercial success of the joint operating activity. Counterparty Name [Axis] Counterparty Name [Axis] Counterparty Name [Domain] Counterparty Name [Domain] Genzyme Genzyme Corporation [Member] Represents information pertaining to Genzyme Corporation, a co-promoter. Genzyme Co-promotion Agreement Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] Number of countries outside United States for exclusive promotion under the agreement Collaborative Arrangement Number of Countries Outside United States in which Marketing Authorization is Obtained Represents the number of countries outside United States in which marketing authorization is obtained under the agreement. Co-promotion fee received from Genzyme Increase (Decrease) in Deferred Revenue Co-promotion fees as a percentage of cash receipts Collaborative Arrangement Co-promotion fees percentage of cash receipts Represents the co-promotion fees paid to co-promoter as a percentage of cash receipts under the agreement. Straight-line amortization period of co-promotion fee Collaborative Arrangement Co Promotion Fee Amortization Period Represents the amortization period of co-promotion fee. Co-promotion fee paid as a percentage of net revenue Collaborative Arrangement Co-promotion Fees Percentage of Net Revenue Represents the co-promotion fees paid to co-promoter as a percentage of net revenue under the agreement. Period of agreement Collaborative Arrangement, Term Represents the term of the co-promotion agreement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Termination notification period Agreement, Termination Notice Represents the minimum period required for providing notice of termination to the agreement. Co-promotion expenses Collaborative Arrangement Co Promotion Expenses Represents the amount of co-promotion expenses incurred under the agreement. Outstanding obligation to Genzyme Collaborative Arrangement Outstanding Obligation Represents the amount of outstanding obligation under the agreement. Amortization of up-front co-promotion fee Award Date [Axis] Award Date [Axis] Award Date [Domain] Award Date [Domain] Class of Stock [Axis] Class of Stock [Axis] Class of Stock [Domain] Class of Stock [Domain] Vesting [Axis] Vesting [Axis] Vesting [Domain] Vesting [Domain] Statement of Financial Position [Abstract] Assets Assets [Abstract] Current assets: Assets, Current [Abstract] Cash and cash equivalents Accounts receivable Accounts Receivable, Net, Current Supplies inventory Inventory, Net Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Restricted cash Restricted Cash and Cash Equivalents, Current Total current assets Assets, Current Property and equipment, net Property, Plant and Equipment, Net Finite-lived intangible assets, net Finite-Lived Intangible Assets, Net Goodwill Goodwill Restricted cash Restricted Cash and Cash Equivalents, Noncurrent Other assets Other Assets, Noncurrent Total assets Assets Liabilities and Stockholders' Equity Liabilities and Equity [Abstract] Current liabilities: Liabilities, Current [Abstract] Accounts payable Accrued liabilities Deferred Genzyme co-promotion fee Deferred Revenue, Current Total current liabilities Liabilities, Current Long-term debt Long-term Debt, Excluding Current Maturities Capital lease liability, net of current portion Capital Lease Obligations Deferred rent, net of current portion Deferred Rent Credit, Noncurrent Total liabilities Liabilities Commitments and contingencies Commitments and Contingencies Stockholders' equity: Stockholders' Equity Attributable to Parent [Abstract] Preferred stock, $0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of December 31, 2016 and 2015 Preferred Stock, Value, Issued Common stock, $0.001 par value; 125,000,000 shares authorized, 33,762,278 and 27,685,291 shares issued and outstanding as of December 31, 2016 and 2015, respectively Common Stock, Value, Issued Additional paid-in capital Additional Paid in Capital, Common Stock Accumulated deficit Retained Earnings (Accumulated Deficit) Total stockholders' equity Total liabilities and stockholders' equity Liabilities and Equity Document and Entity Information Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Document Type Document Type Document Period End Date Document Period End Date Amendment Flag Amendment Flag Current Fiscal Year End Date Current Fiscal Year End Date Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Voluntary Filers Entity Current Reporting Status Entity Current Reporting Status Entity Filer Category Entity Filer Category Entity Public Float Entity Public Float Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Debt instrument, face amount Debt Instrument, Face Amount Debt instrument, unamortized discount 2020 Long-term Debt, Maturities, Repayments of Principal in Year Four 2021 Long-term Debt, Maturities, Repayments of Principal in Year Five 2022 Long-term Debt, Maturities, Repayments of Principal after Year Five Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] IPR&D In Process Research and Development [Member] Nonrecurring Adjustment [Axis] Nonrecurring Adjustment [Axis] Nonrecurring Adjustment [Domain] Nonrecurring Adjustment [Domain] Transaction bonus and other payments to employees and acquisition related costs Transaction Bonuses Other Payments To Employees And Acquisition Related Expenses [Member] Category of transaction bonuses, other payment to employees and acquisition-related costs allocated to (included in) reported pro forma earnings (supplemental pro forma information). Interest expense related to indebtedness of acquired entity Interest Expense Related To Indebtedness Of Acquired Entity [Member] Interest expense related to indebtedness of acquired entity allocated to (included in) reported pro forma earnings (supplemental pro forma information). Number of Allegro shares received for each share of common stock issued and outstanding of a wholly-owned subsidiary of the Company Business Acquisition Number Of Shares Received For Each Subsidiary Share Represents the number of shares of common stock of the acquired entity that each of the issued and outstanding shares of common stock of the subsidiary converted into under the agreement. Conversion right, number of shares Business Acquisition Right To Receive Upon Cancellation Of Preferred Stock Number Of Shares Represents the number of shares of common stock of the reporting entity's subsidiary that the holders of the issued and outstanding preferred stock of the acquired entity had the right to receive upon cancellation under the agreement. Conversion right, cash Business Acquisition Right To Receive Upon Cancellation Of Preferred Stock Cash Represents the amount of cash that the holders of the issued and outstanding preferred stock of the acquired entity had the right to receive upon cancellation under the agreement. Outstanding indebtedness settled in cash Payments To Acquire Businesses Settlement Of Liabilities Incurred The cash outflow as settlement for liabilities incurred by the acquirer as part of consideration transferred in a business combination. Acquisition-related costs Business Acquisition, Transaction Costs Transaction bonuses and severance payments Business Combination, Integration Related Costs Acquisition consideration Business Combination, Consideration Transferred [Abstract] Stock Business Combination, Consideration Transferred, Equity Interests Issued and Issuable Cash Payments to Acquire Businesses, Gross Payment of outstanding indebtedness Business Combination, Consideration Transferred, Liabilities Incurred Total acquisition consideration Business Combination, Consideration Transferred Closing price of Company's common stock Business Acquisition, Share Price Fair value of the assets acquired and liabilities assumed: Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net [Abstract] Cash and cash equivalents Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Cash and Equivalents Other assets, net Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets, Other Amount of other assets acquired at the acquisition date. In-process research and development Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed In Process Research And Development Amount of in-process research and development, having a projected indefinite period of benefit, acquired at the acquisition date. Total acquisition consideration Business Combination, Recognized Identifiable Assets Acquired, Goodwill, and Liabilities Assumed, Net Discount rate (as a percent) Fair Value Inputs, Discount Rate Amortization of IPR&D Accumulated amortization Finite-Lived Intangible Assets, Accumulated Amortization Annual amortization expense expected to be recognized Finite-Lived Intangible Assets, Annual Amortization Expense Amount of annual amortization expense for assets, excluding financial assets and goodwill, lacking physical substance with a finite life expected to be recognized over the useful life of the assets. Amortization expense over each of the next five years Finite-Lived Intangible Assets, Annual Amortization Expense, Next Five Years Amount of annual amortization expense for assets, excluding financial assets and goodwill, lacking physical substance with a finite life expected to be recognized during each of the next five years. Pro-Forma Financial Information Business Acquisition, Pro Forma Information [Abstract] Revenue Business Acquisition, Pro Forma Revenue Net loss Business Acquisition, Pro Forma Net Income (Loss) Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Preferred stock, shares authorized Preferred Stock, Shares Authorized Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Common stock, par value (in dollars per share) Common stock, shares authorized Common stock, shares outstanding Common Stock, Shares, Outstanding Schedule of property and equipment Property, Plant and Equipment [Table Text Block] Schedule of accrued liabilities Schedule of Accrued Liabilities [Table Text Block] Weighted average fair value of options to purchase common stock granted (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Total estimated grant date fair value of options to purchase common stock vested (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value Intrinsic value of stock options exercised (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value Weighted average grant date fair value (in usd per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Compensation and Retirement Disclosure [Abstract] 401(k) Plan Pension and Other Postretirement Benefits Disclosure [Text Block] Revenue Sales Revenue, Net [Member] Lease Arrangement, Type [Axis] Lease Arrangement, Type [Axis] Lease Arrangement, Type [Domain] Lease Arrangement, Type [Domain] Headquarters and laboratory facilities, South San Francisco, Lease expiring 2016 Headquarters And Laboratory Facilities South San Francisco [Member] Represents the lease for headquarters and laboratory space in South San Francisco, California that expires March 2016. Headquarters and laboratory facilities, South San Francisco, Lease signed in April 2015 Headquarters And Laboratory Facilities South San Francisco Lease Two [Member] Represents the lease for headquarters and laboratory space in South San Francisco, California that expires March 2026. Health Care Organization, Revenue Sources [Axis] Health Care Organization, Revenue Sources [Axis] Health Care Organization, Revenue Sources [Domain] Health Care Organization, Revenue Sources [Domain] Medicare Medicare [Member] Represents information pertaining to Medicare, a significant third-party payer. United Healthcare United Healthcare [Member] Represents information pertaining to United Healthcare, a significant third-party payer. Aetna Aetna [Member] Represents information pertaining to Aetna, a significant third-party payer. Concentrations of Credit Risk and Other Risks and Uncertainties Concentrations of Credit Risk and Other Risks and Uncertainties Concentrations of Credit Risk and Other Risks and Uncertainties No definition available. Number of major financial institutions with which the company's cash and cash equivalents are deposited Number of Major Financial Institutions with which Cash and Cash Equivalents Deposited Represents the number of major financial institutions, with which cash and cash equivalents are deposited by the entity. Concentrations of credit risk (as a percent) Concentration Risk, Percentage Restricted Cash Restricted Cash and Investments [Abstract] Amount held as security for lease Security Deposit Long term deposit consisting of letter of credit serving as security for lease Stock Incentive Plans Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Employer contributions to the plan Defined Contribution Plan, Cost Recognized Schedule of reconciliation of tax expense computed at the statutory federal rate and the Company's tax expense Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Schedule of significant components of the Company's deferred tax assets and liabilities Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Schedule of reconciliation of the beginning and ending amount of unrecognized tax benefits Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block] Liquidity Liquidity [Line Items] Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Liquidity Liquidity No definition available. Accumulated deficit Selected Quarterly Financial Data (Unaudited) Selected Quarterly Financial Information [Abstract] Total revenues Net loss per common share, basic and diluted Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Net Loss Per Share Earnings Per Share [Text Block] Genzyme Co-promotion Agreement Collaborative Arrangement Disclosure [Text Block] Interest Expense, Debt [Abstract] Interest Expense, Debt [Abstract] Nominal interest Interest Expense, Debt, Excluding Amortization Amortization of debt discount and debt issuance costs Amortization of Debt Discount (Premium) End-of-term payment Total Interest Expense, Debt Schedule of Capital Leased Assets [Table] Schedule of Capital Leased Assets [Table] Balance Sheet Location [Axis] Balance Sheet Location [Axis] Balance Sheet Location [Domain] Balance Sheet Location [Domain] Accrued Liabilities Accrued Liabilities [Member] Capital Lease Obligations Capital Lease Obligations [Member] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Domain] Property, Plant and Equipment, Type [Domain] Equipment Equipment [Member] Capital Leased Assets [Line Items] Capital Leased Assets [Line Items] Capital leased assets Capital Leased Assets, Gross Capital lease, upfront payment Capital Lease, Upfront Payment Capital Lease, Upfront Payment Capital leases, future minimum payments, present value of net minimum payments Capital Leases, Future Minimum Payments, Present Value of Net Minimum Payments Future minimum payments due Capital Leases, Future Minimum Payments Due Future minimum payments due, 2017 Capital Leases, Future Minimum Payments Due, Next Twelve Months Future minimum payments due, 2018 Capital Leases, Future Minimum Payments Due in Two Years Future minimum payments due, 2019 Capital Leases, Future Minimum Payments Due in Three Years Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Use of Estimates Use of Estimates, Policy [Policy Text Block] Concentrations of Credit Risk and Other Risks and Uncertainties Concentrations of Credit and Other Risks and Uncertainties [Policy Text Block] Disclosure of accounting policy for concentrations of credit risk and other risks and uncertainties. Cash Equivalents Cash and Cash Equivalents, Unrestricted Cash and Cash Equivalents, Policy [Policy Text Block] Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Supplies Inventory Inventory Supplies, Policy [Policy Text Block] Property and Equipment Property, Plant and Equipment, Policy [Policy Text Block] Business Combination Business Combinations Policy [Policy Text Block] Finite-lived Intangible Assets Intangible Assets, Finite-Lived, Policy [Policy Text Block] Goodwill Goodwill and Intangible Assets, Goodwill, Policy [Policy Text Block] Fair Value of Financial Instruments Fair Value of Financial Instruments, Policy [Policy Text Block] Revenue Recognition Revenue Recognition, Policy [Policy Text Block] Cost of Revenue Cost of Sales, Policy [Policy Text Block] Research and Development Research and Development Expense, Policy [Policy Text Block] Income Taxes Income Tax, Policy [Policy Text Block] Stock-based Compensation Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block] Net Loss per Common Share Earnings Per Share, Policy [Policy Text Block] Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Schedule of future principal payments under the Amended Loan Contractual Obligation, Fiscal Year Maturity Schedule [Table Text Block] Schedule of net debt obligation Schedule of Debt [Table Text Block] Schedule of interest expense on debt Interest Income and Interest Expense Disclosure [Table Text Block] Schedule of Operating Leased Assets [Table] Schedule of Operating Leased Assets [Table] Subsequent Event Type [Axis] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Subsequent event Subsequent Event [Member] Laboratory facilities, Austin, Texas Laboratory Facilities Austin Texas [Member] Represents the lease for laboratory facilities in Austin, Texas that expires July 2018. Operating Leases Operating Leased Assets [Line Items] Amount of space leased Lessee Leasing Arrangements, Operating Leases, Space Leased Amount of space leased under the terms of the agreement. Lease Modification, Consideration Received Lease Modification, Consideration Received Lease Modification, Consideration Received Security deposit Future minimum lease payments under non-cancelable operating leases Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract] 2017 Operating Leases, Future Minimum Payments Due, Next Twelve Months 2018 Operating Leases, Future Minimum Payments, Due in Two Years 2019 Operating Leases, Future Minimum Payments, Due in Three Years 2020 Operating Leases, Future Minimum Payments, Due in Four Years 2021 Operating Leases, Future Minimum Payments, Due in Five Years Thereafter Operating Leases, Future Minimum Payments, Due Thereafter Total minimum lease payments Operating Leases, Future Minimum Payments Due Facilities rent expense Operating Leases, Rent Expense, Net Supplies Purchase Commitments Purchase Obligation [Abstract] Non-cancelable purchase commitment Purchase Obligation Term Loan Due 2017 Term Loan Due2017 [Member] Represents the term loan due in June 2017. Term Loan Tranche One Term Loan Tranche One [Member] Represents the first portion of an Amended term loan. Term Loan Tranche Two Term Loan Tranche Two [Member] Represents the second portion of an Amended term loan. Term Loan Tranche Three Term Loan Tranche Three [Member] Represents the third portion of an Amended term loan that may be borrowed anytime through June 30, 2016. Number of tranches Number of Tranches Represents the number of tranches for a term loan. Debt instrument, increase (decrease), net Debt Instrument, Increase (Decrease), Net Debt instrument, unused borrowing capacity, amount Debt Instrument, Unused Borrowing Capacity, Amount Period after which debt is repayable Debt Instrument Period after which Debt is Repayable Represents the period after the date of borrowing in which the debt is repayable under the agreement. Penalty percentage on prepayment within one year of origination Debt Instrument Penalty Percentage on Prepayment within One Year of Origination Represents the percentage of prepayment penalties for prepayment within one year of the loan origination. Penalty percentage on prepayment within two years of origination Debt Instrument Penalty Percentage on Prepayment within Two Years of Origination Represents the percentage of prepayment penalties for prepayment within two years of the loan origination. Penalty percentage on prepayment after two years of origination Debt Instrument Penalty Percentage on Prepayment after Two Years of Origination Represents the percentage of prepayment penalties for prepayment after two years of the loan origination. Proceeds from (repayments of) debt Proceeds from (Repayments of) Debt End of term payment amount Debt Instrument End of Term Payment Amount Represents the amount of obligation for the end of term payment as of the balance sheet date. Payments of debt extinguishment costs Payments of Debt Extinguishment Costs Prepayment premium Debt Instrument, Prepayment Premium Amount of prepayment premium waived. Third party fee, amount paid Debt Instrument, Third Party Fee, Amount Paid Amount of third party fees paid in connection with loan agreement. Class of warrant or right, exercise price of warrants or rights Class of Warrant or Right, Exercise Price of Warrants or Rights Class of warrant or right, number of securities for which warrants will become exercisable in event of conversion of preferred stock into common stock Class of Warrant or Right Number of Securities for which Warrants will Become Exercisable in Event of Conversion of Preferred Stock Into Common Stock Represents the number of securities for which warrants will become exercisable in the event of conversion of outstanding convertible preferred stock into common stock. Fair value of liability Derivative Liability, Current Remaining discount amortization period Debt Instrument Remaining Discount Amortization Period Represents the remaining amortization period for discount on the debt. Debt Debt Disclosure [Text Block] Fair Value Disclosures [Abstract] Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value Measurements, Recurring and Nonrecurring [Table] Asset Class [Axis] Asset Class [Axis] Asset Class [Domain] Asset Class [Domain] Money Market Funds Money Market Funds [Member] Measurement Frequency [Axis] Measurement Frequency [Axis] Fair Value, Measurement Frequency [Domain] Fair Value, Measurement Frequency [Domain] Fair Value, Measurements, Recurring Fair Value, Measurements, Recurring [Member] Fair Value, Hierarchy [Axis] Fair Value, Hierarchy [Axis] Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Fair Value, Inputs, Level 1 Fair Value, Inputs, Level 1 [Member] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Assets, fair value disclosure Assets, Fair Value Disclosure Stock Incentive Plan2013 [Member] Stock Incentive Plan2013 [Member] Represents information pertaining to the 2013 Stock Incentive Plan (the 2013 Plan). NSO Non Statutory Stock Options [Member] Represents information pertaining to non statutory stock options (NSOs). Title of Individual [Axis] Title of Individual [Axis] Relationship to Entity [Domain] Relationship to Entity [Domain] Outside director who was not previously an employee Outside Director Who Was Not Previously Employee [Member] Represents information pertaining to outside director, who was not previously an employee. Outside director serving as a member of Board of Directors for at least six months Outside Director Serving As Member Of Board Of Directors For At Least Six Months [Member] Represents information pertaining to outside director serving as a member of Board of Directors for at least six months. Outside director Outside Director [Member] Nonemployee serving on the board of directors (who collectively have responsibility for governing the entity). Voting power of person owning stock (as a percent) Share Based Compensation Arrangement by Share Based Payment Award Percentage of Voting Power of All Classes of Stock Voting power of all classes of stock, as a percent, of person owning stock as threshold for option terms under the entity's stock option plan. Option price as a percentage of estimated fair value of shares on date of grant to a person owning stock representing more than 10% of voting power of all classes of stock Share based Compensation Arrangement by Share based Payment Award Purchase Price of Stock Percentage for Grants to Persons Who Owned Specified Percentage of Class of Stock Option price as a percentage of estimated fair value of shares on date of grant to a person owning stock representing specified percentage of voting power of all classes of stock. Percentage of award vesting after one year Share based Compensation Arrangement by Share based Payment Award Award Vesting Rights Percentage Year One Percentage of vesting of share-based compensation awards after one year from date of grant. Number of additional shares reserved for issuance Common Stock Capital Additional Shares Reserved for Future Issuance Aggregate number of additional common shares reserved for future issuance under the plan. Maximum annual increase in outstanding shares on the last day of the immediately preceding fiscal year (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Percentage of Outstanding Stock Maximum Number of shares available for issuance Shares granted as annual grant Share Based Compensation Arrangement by Share Based Payment Award Options Annual Grants Gross number of share options (or share units) granted to each individual as an annual grant. Shares granted as initial grant Share Based Compensation Arrangement by Share Based Payment Award Options Initial Grants Gross number of share options (or share units) granted to each individual as an initial grant. Percentage of award granted which vests on a monthly basis Share Based Compensation Arrangement by Share Based Payment Award Award Percentage Vesting on Monthly Basis Percentage of award granted which vests on a monthly basis. Period over which remaining shares will vest on a monthly basis Share Based Compensation Arrangement by Share Based Payment Award Award Period Over which Vesting Will be on Monthly Basis Represents the period over which grants of awards made will vest on a monthly basis. Period for which director has to serve as board of director to receive grant to purchase shares Share Based Compensation Arrangement by Share based Payment Award Period for Which Director Has to Serve as Board of Director to Receive Grant to Purchase Shares Represents the period for which director has to serve as board of director to receive grant to purchase shares. Expiration period after termination of service Share Based Compensation Arrangement by Share Based Payment Award Award Expiration Period After Termination Expiration period of award after termination of service, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Leasehold improvements Leasehold Improvements [Member] Laboratory equipment Computer equipment Computer Equipment [Member] Software, including software developed for internal use Software and Software Development Costs [Member] Furniture and fixtures Furniture and Fixtures [Member] Construction-in-process Construction in Progress [Member] Property and Equipment, Net Property, Plant and Equipment [Line Items] Total property and equipment, at cost Property, Plant and Equipment, Gross Accumulated depreciation and amortization Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Total property and equipment, net Depreciation and amortization expense Depreciation and amortization expense Depreciation and Amortization Expense Depreciation and Amortization Expense Fair Value Measurements Fair Value Disclosures [Text Block] Tax Credit Carryforward [Table] Tax Credit Carryforward [Table] Credit carryforwards Tax Credit Carryforward [Line Items] Credit carryforwards available to reduce future taxable income Tax Credit Carryforward, Amount Reconciliation of the beginning and ending amount of unrecognized tax benefits Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Unrecognized tax benefits, beginning of period Unrecognized Tax Benefits Gross increases-tax position in prior period Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions Gross increases-current period tax position Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions Unrecognized tax benefits, end of period Interest expense or penalties related to unrecognized tax benefits Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense