<?xml version="1.0" encoding="US-ASCII"?>
<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.veracyte.com/role/A401KPlan" xlink:href="vcyt-20191231.xsd#A401KPlan" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/A401KPlanDetails" xlink:href="vcyt-20191231.xsd#A401KPlanDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BalanceSheetComponents" xlink:href="vcyt-20191231.xsd#BalanceSheetComponents" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BalanceSheetComponentsAccruedLiabilitiesDetails" xlink:href="vcyt-20191231.xsd#BalanceSheetComponentsAccruedLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BalanceSheetComponentsAdditionalInformationDetails" xlink:href="vcyt-20191231.xsd#BalanceSheetComponentsAdditionalInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BalanceSheetComponentsFiniteLivedIntangibleAssetsDetails" xlink:href="vcyt-20191231.xsd#BalanceSheetComponentsFiniteLivedIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BalanceSheetComponentsFutureAmortizationDetails" xlink:href="vcyt-20191231.xsd#BalanceSheetComponentsFutureAmortizationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BalanceSheetComponentsPropertyAndEquipmentNetDetails" xlink:href="vcyt-20191231.xsd#BalanceSheetComponentsPropertyAndEquipmentNetDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BalanceSheetComponentsTables" xlink:href="vcyt-20191231.xsd#BalanceSheetComponentsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BusinessCombination" xlink:href="vcyt-20191231.xsd#BusinessCombination" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BusinessCombinationDetails" xlink:href="vcyt-20191231.xsd#BusinessCombinationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BusinessCombinationProFormaFinancialInformationDetails" xlink:href="vcyt-20191231.xsd#BusinessCombinationProFormaFinancialInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BusinessCombinationScheduleOfFairValueOfAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:href="vcyt-20191231.xsd#BusinessCombinationScheduleOfFairValueOfAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BusinessCombinationScheduleOfIdentifiableAcquisitionRelatedIntangiblesDetails" xlink:href="vcyt-20191231.xsd#BusinessCombinationScheduleOfIdentifiableAcquisitionRelatedIntangiblesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/BusinessCombinationTables" xlink:href="vcyt-20191231.xsd#BusinessCombinationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CommitmentsAndContingencies" xlink:href="vcyt-20191231.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CommitmentsAndContingenciesOperatingLeaseDetails" xlink:href="vcyt-20191231.xsd#CommitmentsAndContingenciesOperatingLeaseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CommitmentsAndContingenciesTables" xlink:href="vcyt-20191231.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ConsolidatedBalanceSheets" xlink:href="vcyt-20191231.xsd#ConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:href="vcyt-20191231.xsd#ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ConsolidatedStatementsOfCashFlows" xlink:href="vcyt-20191231.xsd#ConsolidatedStatementsOfCashFlows" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:href="vcyt-20191231.xsd#ConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ConsolidatedStatementsOfStockholdersEquity" xlink:href="vcyt-20191231.xsd#ConsolidatedStatementsOfStockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ConsolidatedStatementsOfStockholdersEquityParenthetical" xlink:href="vcyt-20191231.xsd#ConsolidatedStatementsOfStockholdersEquityParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CoverPage" xlink:href="vcyt-20191231.xsd#CoverPage" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/Debt" xlink:href="vcyt-20191231.xsd#Debt" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtCreditAgreementDetails" xlink:href="vcyt-20191231.xsd#DebtCreditAgreementDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtInterestExpenseDetails" xlink:href="vcyt-20191231.xsd#DebtInterestExpenseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtLoanAndSecurityAgreementDetails" xlink:href="vcyt-20191231.xsd#DebtLoanAndSecurityAgreementDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtScheduleOfLoanAndSecurityAgreementDetails" xlink:href="vcyt-20191231.xsd#DebtScheduleOfLoanAndSecurityAgreementDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtTables" xlink:href="vcyt-20191231.xsd#DebtTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/FairValueMeasurements" xlink:href="vcyt-20191231.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/FairValueMeasurementsDetails" xlink:href="vcyt-20191231.xsd#FairValueMeasurementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxes" xlink:href="vcyt-20191231.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxesAdditionalInformationDetails" xlink:href="vcyt-20191231.xsd#IncomeTaxesAdditionalInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:href="vcyt-20191231.xsd#IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxesIncomeTaxExaminationDetails" xlink:href="vcyt-20191231.xsd#IncomeTaxesIncomeTaxExaminationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxesTables" xlink:href="vcyt-20191231.xsd#IncomeTaxesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxesTaxProvisionDetails" xlink:href="vcyt-20191231.xsd#IncomeTaxesTaxProvisionDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxesUncertainTaxPositionsDetails" xlink:href="vcyt-20191231.xsd#IncomeTaxesUncertainTaxPositionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/NetLossPerShare" xlink:href="vcyt-20191231.xsd#NetLossPerShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/NetLossPerShareDetails" xlink:href="vcyt-20191231.xsd#NetLossPerShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/NetLossPerShareTables" xlink:href="vcyt-20191231.xsd#NetLossPerShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusiness" xlink:href="vcyt-20191231.xsd#OrganizationAndDescriptionOfBusiness" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessDetails" xlink:href="vcyt-20191231.xsd#OrganizationAndDescriptionOfBusinessDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SelectedQuarterlyFinancialDataUnaudited" xlink:href="vcyt-20191231.xsd#SelectedQuarterlyFinancialDataUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SelectedQuarterlyFinancialDataUnauditedDetails" xlink:href="vcyt-20191231.xsd#SelectedQuarterlyFinancialDataUnauditedDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SelectedQuarterlyFinancialDataUnauditedTables" xlink:href="vcyt-20191231.xsd#SelectedQuarterlyFinancialDataUnauditedTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockIncentivePlans" xlink:href="vcyt-20191231.xsd#StockIncentivePlans" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockIncentivePlansActivityUnderStockOptionPlansDetails" xlink:href="vcyt-20191231.xsd#StockIncentivePlansActivityUnderStockOptionPlansDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockIncentivePlansAdditionalInformationDetails" xlink:href="vcyt-20191231.xsd#StockIncentivePlansAdditionalInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockIncentivePlansStockBasedCompensationDetails" xlink:href="vcyt-20191231.xsd#StockIncentivePlansStockBasedCompensationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockIncentivePlansStockIncentivePlansEsppDetails" xlink:href="vcyt-20191231.xsd#StockIncentivePlansStockIncentivePlansEsppDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockIncentivePlansStockOptionPlansDetails" xlink:href="vcyt-20191231.xsd#StockIncentivePlansStockOptionPlansDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockIncentivePlansTables" xlink:href="vcyt-20191231.xsd#StockIncentivePlansTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockholdersEquity" xlink:href="vcyt-20191231.xsd#StockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockholdersEquityDetails" xlink:href="vcyt-20191231.xsd#StockholdersEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockholdersEquityTables" xlink:href="vcyt-20191231.xsd#StockholdersEquityTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesCreditRiskRestrictedCashAndAllowanceForDoubtfulAccountsDetails" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPoliciesCreditRiskRestrictedCashAndAllowanceForDoubtfulAccountsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesDiagnosticDevelopmentAgreementWithJohnsonJohnsonDetails" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPoliciesDiagnosticDevelopmentAgreementWithJohnsonJohnsonDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesIntangibleAssetsBonusAccrualsAndRevenueRecognitionDetails" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPoliciesIntangibleAssetsBonusAccrualsAndRevenueRecognitionDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesLiquidityDetails" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPoliciesLiquidityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesRecentAccountingPronouncementsDetails" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPoliciesRecentAccountingPronouncementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesTables" xlink:href="vcyt-20191231.xsd#SummaryOfSignificantAccountingPoliciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ThyroidCytopathologyPartners" xlink:href="vcyt-20191231.xsd#ThyroidCytopathologyPartners" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ThyroidCytopathologyPartnersDetails" xlink:href="vcyt-20191231.xsd#ThyroidCytopathologyPartnersDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <link:presentationLink xlink:role="http://www.veracyte.com/role/A401KPlan" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_719129B87C4B5446550FE8A9968F7979" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock" xlink:label="loc_us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock_542AD09F1EB8DE577E64E8A9968F979D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_719129B87C4B5446550FE8A9968F7979" xlink:to="loc_us-gaap_PensionAndOtherPostretirementBenefitsDisclosureTextBlock_542AD09F1EB8DE577E64E8A9968F979D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/A401KPlanDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CompensationAndRetirementDisclosureAbstract" xlink:label="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_AEEB067CFBAA73A5CB9DE8A9968923C3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DefinedContributionPlanCostRecognized" xlink:label="loc_us-gaap_DefinedContributionPlanCostRecognized_804F1D084B066A16E682E8A9968A3B5B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CompensationAndRetirementDisclosureAbstract_AEEB067CFBAA73A5CB9DE8A9968923C3" xlink:to="loc_us-gaap_DefinedContributionPlanCostRecognized_804F1D084B066A16E682E8A9968A3B5B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BalanceSheetComponents" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_845B1CBBE5143EC1B553E8A9992C0655" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SupplementalBalanceSheetDisclosuresTextBlock" xlink:label="loc_us-gaap_SupplementalBalanceSheetDisclosuresTextBlock_949E77208B38216FEC2BE8A9992C560B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_845B1CBBE5143EC1B553E8A9992C0655" xlink:to="loc_us-gaap_SupplementalBalanceSheetDisclosuresTextBlock_949E77208B38216FEC2BE8A9992C560B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BalanceSheetComponentsAccruedLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_EE111831EA02DEFC4CD9E8A999099596" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccruedLiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_489D6937AEAF7A587EC2E8A9990979C2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_EE111831EA02DEFC4CD9E8A999099596" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_489D6937AEAF7A587EC2E8A9990979C2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_FB2F97DA00E5A934BA96E8A99909C555" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_489D6937AEAF7A587EC2E8A9990979C2" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_FB2F97DA00E5A934BA96E8A99909C555" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_25CDE80A63B79B11EC28E8A9990A0AFD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_489D6937AEAF7A587EC2E8A9990979C2" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_25CDE80A63B79B11EC28E8A9990A0AFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_09DA5ADED5179F880D0EE8A9990A7274" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrentAbstract_489D6937AEAF7A587EC2E8A9990979C2" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_09DA5ADED5179F880D0EE8A9990A7274" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BalanceSheetComponentsAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_809CA29C20AB00E876F9F77DA16086A4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_B0BF5A9513026DF5EE12F77DEAD7CE13" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_809CA29C20AB00E876F9F77DA16086A4" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_B0BF5A9513026DF5EE12F77DEAD7CE13" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BalanceSheetComponentsFiniteLivedIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_84008CB32DBCB2DB8B4964AA520CFE82" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_37CBA40756C792494D5264AA520CC429" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_84008CB32DBCB2DB8B4964AA520CFE82" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_37CBA40756C792494D5264AA520CC429" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_545C56F3B00AE7FF944064AA520C2906" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_37CBA40756C792494D5264AA520CC429" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_545C56F3B00AE7FF944064AA520C2906" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B52C75C93C624C0F1E5E64AA520D0A48" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_545C56F3B00AE7FF944064AA520C2906" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B52C75C93C624C0F1E5E64AA520D0A48" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_PerceptaTechnologyMember" xlink:label="loc_vcyt_PerceptaTechnologyMember_F2C470F53EB9B794DB1964AA520D67B2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B52C75C93C624C0F1E5E64AA520D0A48" xlink:to="loc_vcyt_PerceptaTechnologyMember_F2C470F53EB9B794DB1964AA520D67B2" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DevelopedProductTechnologyMember" xlink:label="loc_vcyt_DevelopedProductTechnologyMember_2B59F8D12A60B4797FB864AA520DC5A9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B52C75C93C624C0F1E5E64AA520D0A48" xlink:to="loc_vcyt_DevelopedProductTechnologyMember_2B59F8D12A60B4797FB864AA520DC5A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CustomerRelationshipsMember" xlink:label="loc_us-gaap_CustomerRelationshipsMember_6E4AE64387601C04335C64AA520E9879" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B52C75C93C624C0F1E5E64AA520D0A48" xlink:to="loc_us-gaap_CustomerRelationshipsMember_6E4AE64387601C04335C64AA520E9879" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NCounterFLEXDxLicenseMember" xlink:label="loc_vcyt_NCounterFLEXDxLicenseMember_5B4F26F7AC14D077137F64AA520ED5D3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B52C75C93C624C0F1E5E64AA520D0A48" xlink:to="loc_vcyt_NCounterFLEXDxLicenseMember_5B4F26F7AC14D077137F64AA520ED5D3" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_AZCollaborationLicenseMember" xlink:label="loc_vcyt_AZCollaborationLicenseMember_A0BFB9A07E8031FC912B64AA520E88F5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_B52C75C93C624C0F1E5E64AA520D0A48" xlink:to="loc_vcyt_AZCollaborationLicenseMember_A0BFB9A07E8031FC912B64AA520E88F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_B34E0FF1874EA534C4A164AA520E3345" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_37CBA40756C792494D5264AA520CC429" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_B34E0FF1874EA534C4A164AA520E3345" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_55BF7C927B33676D6C4A64AA520E1DBF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_B34E0FF1874EA534C4A164AA520E3345" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_55BF7C927B33676D6C4A64AA520E1DBF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_BADEC6B7D175976D436464AA520F1C53" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_B34E0FF1874EA534C4A164AA520E3345" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_BADEC6B7D175976D436464AA520F1C53" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_62C2FEDC8AB4F74FA73A64AA520F727D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_B34E0FF1874EA534C4A164AA520E3345" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_62C2FEDC8AB4F74FA73A64AA520F727D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_609AA27D89418515703464AA520FA1E3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_B34E0FF1874EA534C4A164AA520E3345" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_609AA27D89418515703464AA520FA1E3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BalanceSheetComponentsFutureAmortizationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_17D9C37F5E0B2153229FF7751A0F290B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_17D9C37F5E0B2153229FF7751A0F290B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_D269C76AFA93866C29C3F7751A194976" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_D269C76AFA93866C29C3F7751A194976" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_29FC8F0A0F53D2834B58F7751A21C343" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_29FC8F0A0F53D2834B58F7751A21C343" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_D673F297AB75E70ABF47F7751A2666D6" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_D673F297AB75E70ABF47F7751A2666D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_81B720F605DB9DEBACADF7751A261C92" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_81B720F605DB9DEBACADF7751A261C92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_F89B9E33FDF2D9F2A536F7751A36C82D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_F89B9E33FDF2D9F2A536F7751A36C82D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_F94166E636011E0B5843F7751A452C35" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_503FFC30D3134F5A0245F773DFA5C2F1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_F94166E636011E0B5843F7751A452C35" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BalanceSheetComponentsPropertyAndEquipmentNetDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_911A665B9F29208214EF7A1C559B370C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_A56554663D4EF50A91E07A1C559BD65E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_911A665B9F29208214EF7A1C559B370C" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_A56554663D4EF50A91E07A1C559BD65E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_0312B3FDF475FC99EC9B7A1C559C7E35" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_A56554663D4EF50A91E07A1C559BD65E" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_0312B3FDF475FC99EC9B7A1C559C7E35" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_0312B3FDF475FC99EC9B7A1C559C7E35" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseholdImprovementsMember" xlink:label="loc_us-gaap_LeaseholdImprovementsMember_69FB359B2D3E401A6F267A1C559C70C7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:to="loc_us-gaap_LeaseholdImprovementsMember_69FB359B2D3E401A6F267A1C559C70C7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsLeasedToOthersMember" xlink:label="loc_us-gaap_AssetsLeasedToOthersMember_D1512C71BA70649262867A1C559C05C0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:to="loc_us-gaap_AssetsLeasedToOthersMember_D1512C71BA70649262867A1C559C05C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ComputerEquipmentMember" xlink:label="loc_us-gaap_ComputerEquipmentMember_7A88322432D7C8BA51357A1C559DA106" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:to="loc_us-gaap_ComputerEquipmentMember_7A88322432D7C8BA51357A1C559DA106" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SoftwareAndSoftwareDevelopmentCostsMember" xlink:label="loc_us-gaap_SoftwareAndSoftwareDevelopmentCostsMember_BA81B232D3C9DA2829AD7A1C559D97E7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:to="loc_us-gaap_SoftwareAndSoftwareDevelopmentCostsMember_BA81B232D3C9DA2829AD7A1C559D97E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FurnitureAndFixturesMember" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_6EB0C57B1642DFBBBCC77A1C559DEAA2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_6EB0C57B1642DFBBBCC77A1C559DEAA2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConstructionInProgressMember" xlink:label="loc_us-gaap_ConstructionInProgressMember_5DCF5ACDBC5F372809AD7A1C559DB6A5" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F2840A73547EBFC4F0E77A1C559CE9B6" xlink:to="loc_us-gaap_ConstructionInProgressMember_5DCF5ACDBC5F372809AD7A1C559DB6A5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_A56554663D4EF50A91E07A1C559BD65E" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_DD8C5D75B5E22993F4AC7A1C559D9068" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_DD8C5D75B5E22993F4AC7A1C559D9068" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_A56FF5D75B6412C7AD9A7A1C559EBA3D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_A56FF5D75B6412C7AD9A7A1C559EBA3D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_04B9069617F7230B093F7A1C559ED82C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_04B9069617F7230B093F7A1C559ED82C" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DepreciationandAmortizationofTangibleAssets" xlink:label="loc_vcyt_DepreciationandAmortizationofTangibleAssets_E450970B49A53774721B7A1C559E543A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:to="loc_vcyt_DepreciationandAmortizationofTangibleAssets_E450970B49A53774721B7A1C559E543A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_FinanceLeaseRightofUseAssetbeforeAccumulatedAmortization" xlink:label="loc_vcyt_FinanceLeaseRightofUseAssetbeforeAccumulatedAmortization_2514408A403E98ECD2717A1C559E5F87" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:to="loc_vcyt_FinanceLeaseRightofUseAssetbeforeAccumulatedAmortization_2514408A403E98ECD2717A1C559E5F87" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_FinanceLeaseRightofUseAssetAccumulatedAmortization" xlink:label="loc_vcyt_FinanceLeaseRightofUseAssetAccumulatedAmortization_5605506132DE6664BFF17A1C559E0B8B" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:to="loc_vcyt_FinanceLeaseRightofUseAssetAccumulatedAmortization_5605506132DE6664BFF17A1C559E0B8B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAssetAmortization" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_810D9B4531CECE97475D7A1C559E253E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_05E187ACC78C86F837AE7A1C559D6FB1" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAssetAmortization_810D9B4531CECE97475D7A1C559E253E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BalanceSheetComponentsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_37D0673A6D238494FA7CF731FF4CA484" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_AEA3229E508953FEA5B3F731FF4C1DF5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_37D0673A6D238494FA7CF731FF4CA484" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_AEA3229E508953FEA5B3F731FF4C1DF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfIntangibleAssetsAndGoodwillTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfIntangibleAssetsAndGoodwillTableTextBlock_7D17C0A1F95E17F46432F77BE1078401" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_37D0673A6D238494FA7CF731FF4CA484" xlink:to="loc_us-gaap_ScheduleOfIntangibleAssetsAndGoodwillTableTextBlock_7D17C0A1F95E17F46432F77BE1078401" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock" xlink:label="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_B86C9A3F1F55240D5C04F77A278B9D3B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_37D0673A6D238494FA7CF731FF4CA484" xlink:to="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_B86C9A3F1F55240D5C04F77A278B9D3B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_C5FA3DD56E00769ACCB1F731FF4C21BA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_37D0673A6D238494FA7CF731FF4CA484" xlink:to="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_C5FA3DD56E00769ACCB1F731FF4C21BA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BusinessCombination" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_40FB0F0F2E432A3AE4F4E8A9996052D6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock" xlink:label="loc_us-gaap_BusinessCombinationDisclosureTextBlock_47F040D715130C4C94BFE8A999604042" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_40FB0F0F2E432A3AE4F4E8A9996052D6" xlink:to="loc_us-gaap_BusinessCombinationDisclosureTextBlock_47F040D715130C4C94BFE8A999604042" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BusinessCombinationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_7DD6109E1C6145B2C8F9402FCF87F409" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_D48C27209F9478C4D6BE402FCF87B85A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_7DD6109E1C6145B2C8F9402FCF87F409" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_D48C27209F9478C4D6BE402FCF87B85A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityInterestIssuedOrIssuableByTypeAxis" xlink:label="loc_us-gaap_EquityInterestIssuedOrIssuableByTypeAxis_DFC5CE4EA63D069F75FE405816BCB6DD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_D48C27209F9478C4D6BE402FCF87B85A" xlink:to="loc_us-gaap_EquityInterestIssuedOrIssuableByTypeAxis_DFC5CE4EA63D069F75FE405816BCB6DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityInterestIssuedOrIssuableTypeDomain" xlink:label="loc_us-gaap_EquityInterestIssuedOrIssuableTypeDomain_A9F6653FDB9457ADB2DD4058E4D40DE6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityInterestIssuedOrIssuableByTypeAxis_DFC5CE4EA63D069F75FE405816BCB6DD" xlink:to="loc_us-gaap_EquityInterestIssuedOrIssuableTypeDomain_A9F6653FDB9457ADB2DD4058E4D40DE6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_45AF99A15737DB52387A40590C837723" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityInterestIssuedOrIssuableTypeDomain_A9F6653FDB9457ADB2DD4058E4D40DE6" xlink:to="loc_us-gaap_CommonStockMember_45AF99A15737DB52387A40590C837723" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_A806B7E27F0CA8ACC331402FCF88FBF8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_D48C27209F9478C4D6BE402FCF87B85A" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_A806B7E27F0CA8ACC331402FCF88FBF8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_5A48D0780089301F804F402FCF88A181" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_A806B7E27F0CA8ACC331402FCF88FBF8" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_5A48D0780089301F804F402FCF88A181" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NanoStringMember" xlink:label="loc_vcyt_NanoStringMember_A2B00CE7978553547250405FF0F2C3C5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_5A48D0780089301F804F402FCF88A181" xlink:to="loc_vcyt_NanoStringMember_A2B00CE7978553547250405FF0F2C3C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_17E33DAE68E03FE87FA0402FCF8B8A60" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_D48C27209F9478C4D6BE402FCF87B85A" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_17E33DAE68E03FE87FA0402FCF8B8A60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_EAF24DBF7F3F2C6FAD54406A338F0AEE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_17E33DAE68E03FE87FA0402FCF8B8A60" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_EAF24DBF7F3F2C6FAD54406A338F0AEE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable_9D1A4EA8D0862820E006406A33989136" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_17E33DAE68E03FE87FA0402FCF8B8A60" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable_9D1A4EA8D0862820E006406A33989136" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_BusinessCombinationContingentConsiderationCashtobePaid" xlink:label="loc_vcyt_BusinessCombinationContingentConsiderationCashtobePaid_C4CE99F3952436C5FD90406A339F542B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_17E33DAE68E03FE87FA0402FCF8B8A60" xlink:to="loc_vcyt_BusinessCombinationContingentConsiderationCashtobePaid_C4CE99F3952436C5FD90406A339F542B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_68126B9C16FF58A969E6406A33A70BD9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_17E33DAE68E03FE87FA0402FCF8B8A60" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_68126B9C16FF58A969E6406A33A70BD9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_85DD91E3FE4734F19C86406A5709FBB0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_17E33DAE68E03FE87FA0402FCF8B8A60" xlink:to="loc_us-gaap_Goodwill_85DD91E3FE4734F19C86406A5709FBB0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BusinessCombinationProFormaFinancialInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_D1A3802CB5AAFD11D54D7CA1594D8506" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_2B66A834976A084B849B7CA1594D2345" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_D1A3802CB5AAFD11D54D7CA1594D8506" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_2B66A834976A084B849B7CA1594D2345" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_BE841F3AB685D91264157CA1594FD621" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_2B66A834976A084B849B7CA1594D2345" xlink:to="loc_srt_ProductOrServiceAxis_BE841F3AB685D91264157CA1594FD621" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_7DE76614A4342D47EB457CA1594F3F68" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_BE841F3AB685D91264157CA1594FD621" xlink:to="loc_srt_ProductsAndServicesDomain_7DE76614A4342D47EB457CA1594F3F68" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductMember" xlink:label="loc_us-gaap_ProductMember_E23DFCF773BFA0DB109F7CA1594F5B90" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_7DE76614A4342D47EB457CA1594F3F68" xlink:to="loc_us-gaap_ProductMember_E23DFCF773BFA0DB109F7CA1594F5B90" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_5B1D7CCC4067F66C43FC7CA159507881" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_2B66A834976A084B849B7CA1594D2345" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_5B1D7CCC4067F66C43FC7CA159507881" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ACE7027C67299D935EF47CA159506B0B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_5B1D7CCC4067F66C43FC7CA159507881" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ACE7027C67299D935EF47CA159506B0B" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NanoStringMember" xlink:label="loc_vcyt_NanoStringMember_1F776B4A518710B6A59C7CA15950501F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_ACE7027C67299D935EF47CA159506B0B" xlink:to="loc_vcyt_NanoStringMember_1F776B4A518710B6A59C7CA15950501F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_0CD44592AC6DFC264CE27CA15951B1B4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_2B66A834976A084B849B7CA1594D2345" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_0CD44592AC6DFC264CE27CA15951B1B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionsProFormaRevenue" xlink:label="loc_us-gaap_BusinessAcquisitionsProFormaRevenue_2E2A42918738442344707CA2466C51D9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_0CD44592AC6DFC264CE27CA15951B1B4" xlink:to="loc_us-gaap_BusinessAcquisitionsProFormaRevenue_2E2A42918738442344707CA2466C51D9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BusinessCombinationScheduleOfFairValueOfAssetsAcquiredAndLiabilitiesAssumedDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_3C2045B43EF0D6B01C06654D90D7A038" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_13D6EF2B28743BC06F77654D90D85DCF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_3C2045B43EF0D6B01C06654D90D7A038" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_13D6EF2B28743BC06F77654D90D85DCF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_427CB7C730A7D4BED2E1654D90D873D0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_13D6EF2B28743BC06F77654D90D85DCF" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_427CB7C730A7D4BED2E1654D90D873D0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0A16A264434F9D18E7A4654D90D9304D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_427CB7C730A7D4BED2E1654D90D873D0" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0A16A264434F9D18E7A4654D90D9304D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DevelopedProductTechnologyMember" xlink:label="loc_vcyt_DevelopedProductTechnologyMember_C4C92328A619B6D46C45654D90D9E0DD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0A16A264434F9D18E7A4654D90D9304D" xlink:to="loc_vcyt_DevelopedProductTechnologyMember_C4C92328A619B6D46C45654D90D9E0DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CustomerRelationshipsMember" xlink:label="loc_us-gaap_CustomerRelationshipsMember_CB04B6D1A3917A0A21A0654D90D958E4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0A16A264434F9D18E7A4654D90D9304D" xlink:to="loc_us-gaap_CustomerRelationshipsMember_CB04B6D1A3917A0A21A0654D90D958E4" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NCounterFLEXDxLicenseMember" xlink:label="loc_vcyt_NCounterFLEXDxLicenseMember_C32EF969300094C7BA08654D90DA02C2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0A16A264434F9D18E7A4654D90D9304D" xlink:to="loc_vcyt_NCounterFLEXDxLicenseMember_C32EF969300094C7BA08654D90DA02C2" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_AZCollaborationLicenseMember" xlink:label="loc_vcyt_AZCollaborationLicenseMember_C2682D44404F8BB44F78654D90DA39E0" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0A16A264434F9D18E7A4654D90D9304D" xlink:to="loc_vcyt_AZCollaborationLicenseMember_C2682D44404F8BB44F78654D90DA39E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_0AE3C486E3FD934FD895654D90DA5A6B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_13D6EF2B28743BC06F77654D90D85DCF" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_0AE3C486E3FD934FD895654D90DA5A6B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_B14C40AD4B01B8D91938654D90DB9446" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_0AE3C486E3FD934FD895654D90DA5A6B" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_B14C40AD4B01B8D91938654D90DB9446" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NanoStringMember" xlink:label="loc_vcyt_NanoStringMember_FC3CED1B73E98E713EA3654D90E0818F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_B14C40AD4B01B8D91938654D90DB9446" xlink:to="loc_vcyt_NanoStringMember_FC3CED1B73E98E713EA3654D90E0818F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_D88FC97C97929FDECB8D654D90E0584F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_13D6EF2B28743BC06F77654D90D85DCF" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_D88FC97C97929FDECB8D654D90E0584F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_9902EBAD9D0262BEC5E4654D90E10D5E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_D88FC97C97929FDECB8D654D90E0584F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_9902EBAD9D0262BEC5E4654D90E10D5E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_34F9A2DCD0B47D4BD2DA654D90E2F0CB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_D88FC97C97929FDECB8D654D90E0584F" xlink:to="loc_us-gaap_Goodwill_34F9A2DCD0B47D4BD2DA654D90E2F0CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_08B80805C71957A377B9654D90E2F38E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_D88FC97C97929FDECB8D654D90E0584F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_08B80805C71957A377B9654D90E2F38E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BusinessCombinationScheduleOfIdentifiableAcquisitionRelatedIntangiblesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_AC6A4467A38B9D05D6F5598B710F0FC0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CD63855432310C4BF353598B710F6AF4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_AC6A4467A38B9D05D6F5598B710F0FC0" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CD63855432310C4BF353598B710F6AF4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_0886C28CF1CC5495BAAD598B7110C88A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CD63855432310C4BF353598B710F6AF4" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_0886C28CF1CC5495BAAD598B7110C88A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E3C4490BBC13CD65F913598B7110F3DB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_0886C28CF1CC5495BAAD598B7110C88A" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E3C4490BBC13CD65F913598B7110F3DB" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DevelopedProductTechnologyMember" xlink:label="loc_vcyt_DevelopedProductTechnologyMember_0BB6676A06B46F57502E598B7110BC80" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E3C4490BBC13CD65F913598B7110F3DB" xlink:to="loc_vcyt_DevelopedProductTechnologyMember_0BB6676A06B46F57502E598B7110BC80" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CustomerRelationshipsMember" xlink:label="loc_us-gaap_CustomerRelationshipsMember_0049884E36954F042054598B711011E6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E3C4490BBC13CD65F913598B7110F3DB" xlink:to="loc_us-gaap_CustomerRelationshipsMember_0049884E36954F042054598B711011E6" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NCounterFLEXDxLicenseMember" xlink:label="loc_vcyt_NCounterFLEXDxLicenseMember_F07104C633BB5126E418598B7111D67D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E3C4490BBC13CD65F913598B7110F3DB" xlink:to="loc_vcyt_NCounterFLEXDxLicenseMember_F07104C633BB5126E418598B7111D67D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_AZCollaborationLicenseMember" xlink:label="loc_vcyt_AZCollaborationLicenseMember_08574A3F659F53EA9D48598B7111BAAF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_E3C4490BBC13CD65F913598B7110F3DB" xlink:to="loc_vcyt_AZCollaborationLicenseMember_08574A3F659F53EA9D48598B7111BAAF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_396C45A5695F609D8602598B71113C13" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CD63855432310C4BF353598B710F6AF4" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_396C45A5695F609D8602598B71113C13" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FDFB1562D8C842548BF1598B7111ADA7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_396C45A5695F609D8602598B71113C13" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FDFB1562D8C842548BF1598B7111ADA7" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NanoStringMember" xlink:label="loc_vcyt_NanoStringMember_D7B8A5A5E4C0BCBE1F49598B7111FCE5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_FDFB1562D8C842548BF1598B7111ADA7" xlink:to="loc_vcyt_NanoStringMember_D7B8A5A5E4C0BCBE1F49598B7111FCE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_33AA399719FE11E325AE598B7112A630" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CD63855432310C4BF353598B710F6AF4" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_33AA399719FE11E325AE598B7112A630" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife" xlink:label="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_B99D067B9BF110CB1FC0598B7112797A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_33AA399719FE11E325AE598B7112A630" xlink:to="loc_us-gaap_AcquiredFiniteLivedIntangibleAssetsWeightedAverageUsefulLife_B99D067B9BF110CB1FC0598B7112797A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/BusinessCombinationTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationsAbstract" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_4CD32A7C01EF4E07C8445FE4DF2DA55E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_562D4A27791E78BC52925FE4DF2E5E3B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_4CD32A7C01EF4E07C8445FE4DF2DA55E" xlink:to="loc_us-gaap_ScheduleOfRecognizedIdentifiedAssetsAcquiredAndLiabilitiesAssumedTableTextBlock_562D4A27791E78BC52925FE4DF2E5E3B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsAcquiredAsPartOfBusinessCombinationTextBlock" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsAcquiredAsPartOfBusinessCombinationTextBlock_C0C081586E81C1332C155FE4DF2FAE07" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_4CD32A7C01EF4E07C8445FE4DF2DA55E" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsAcquiredAsPartOfBusinessCombinationTextBlock_C0C081586E81C1332C155FE4DF2FAE07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionProFormaInformationTextBlock" xlink:label="loc_us-gaap_BusinessAcquisitionProFormaInformationTextBlock_939955926B4940DCBBE95FE73F8BFD7B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_4CD32A7C01EF4E07C8445FE4DF2DA55E" xlink:to="loc_us-gaap_BusinessAcquisitionProFormaInformationTextBlock_939955926B4940DCBBE95FE73F8BFD7B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CommitmentsAndContingencies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_58D5ED672494EDD4921DE8A998EB5169" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_960850BD07818AD377C4E8A998EBA782" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_58D5ED672494EDD4921DE8A998EB5169" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_960850BD07818AD377C4E8A998EBA782" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CommitmentsAndContingenciesOperatingLeaseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_7B4E80080F60C4CA5D6D7CA1590861B1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfOperatingLeasedAssetsTable" xlink:label="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_96CAB6118528869852B17CA15908EFF4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_7B4E80080F60C4CA5D6D7CA1590861B1" xlink:to="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_96CAB6118528869852B17CA15908EFF4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseArrangementTypeAxis" xlink:label="loc_us-gaap_LeaseArrangementTypeAxis_AAFE9F65C0CC3C989D9C7CA1590955EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_96CAB6118528869852B17CA15908EFF4" xlink:to="loc_us-gaap_LeaseArrangementTypeAxis_AAFE9F65C0CC3C989D9C7CA1590955EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseArrangementTypeDomain" xlink:label="loc_us-gaap_LeaseArrangementTypeDomain_FDB568FE8ABCA732B5347CA15909F8D5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeAxis_AAFE9F65C0CC3C989D9C7CA1590955EA" xlink:to="loc_us-gaap_LeaseArrangementTypeDomain_FDB568FE8ABCA732B5347CA15909F8D5" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember" xlink:label="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_B71613717E81C5C5BA537CA15909DB10" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeDomain_FDB568FE8ABCA732B5347CA15909F8D5" xlink:to="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_B71613717E81C5C5BA537CA15909DB10" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_LaboratoryFacilitiesAustinTexasMember" xlink:label="loc_vcyt_LaboratoryFacilitiesAustinTexasMember_93B001695192F71938217CA1590A686B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeDomain_FDB568FE8ABCA732B5347CA15909F8D5" xlink:to="loc_vcyt_LaboratoryFacilitiesAustinTexasMember_93B001695192F71938217CA1590A686B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasedAssetsLineItems" xlink:label="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_96CAB6118528869852B17CA15908EFF4" xlink:to="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_LesseeLeasingArrangementsOperatingLeasesSpaceLeased" xlink:label="loc_vcyt_LesseeLeasingArrangementsOperatingLeasesSpaceLeased_6A86459934B6F01D76A97CA1590A4705" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:to="loc_vcyt_LesseeLeasingArrangementsOperatingLeasesSpaceLeased_6A86459934B6F01D76A97CA1590A4705" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SecurityDeposit" xlink:label="loc_us-gaap_SecurityDeposit_E110ACD17B86999900887CA1590AA008" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:to="loc_us-gaap_SecurityDeposit_E110ACD17B86999900887CA1590AA008" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseDiscountRate" xlink:label="loc_us-gaap_LesseeOperatingLeaseDiscountRate_E73D484401B2BA773CEF7CA1590A5B68" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:to="loc_us-gaap_LesseeOperatingLeaseDiscountRate_E73D484401B2BA773CEF7CA1590A5B68" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseExpense" xlink:label="loc_us-gaap_OperatingLeaseExpense_E6241A212FEC7369B60B7CA1590AB59A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:to="loc_us-gaap_OperatingLeaseExpense_E6241A212FEC7369B60B7CA1590AB59A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PurchaseObligation" xlink:label="loc_us-gaap_PurchaseObligation_E4CB1D44BA7F0D4FDD9E7CA1590BDC90" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:to="loc_us-gaap_PurchaseObligation_E4CB1D44BA7F0D4FDD9E7CA1590BDC90" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_62446852BC108E34513E7CA1590A9338" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_85E9262AAC863635F4D17CA1590B333E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_85E9262AAC863635F4D17CA1590B333E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_BFDAE5F5651AEB736BC47CA1590B527A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_BFDAE5F5651AEB736BC47CA1590B527A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_52B8457F05EC55CF4DF67CA1590C36AE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_52B8457F05EC55CF4DF67CA1590C36AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_39CFA5FCA2471C3A75BE7CA1590C458E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_39CFA5FCA2471C3A75BE7CA1590C458E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_2191A431F8895DC662307CA1590CB309" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_2191A431F8895DC662307CA1590CB309" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_7CD745F5B073E070C2997CA1590C31D2" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_7CD745F5B073E070C2997CA1590C31D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_B54B396D157FA487CCC17CA1590CE948" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_B54B396D157FA487CCC17CA1590CE948" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_279E04E0BA811B40DA867CA1590CB71D" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_279E04E0BA811B40DA867CA1590CB71D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="loc_us-gaap_OperatingLeaseLiability_768B27449233C0A68A667CA1590DA57A" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_OperatingLeaseLiability_768B27449233C0A68A667CA1590DA57A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_E8BD23C9C27626B672A47CA1590DEFF4" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_E8BD23C9C27626B672A47CA1590DEFF4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_809EFA007006AD35B42F7CA1590DE030" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_383A1A442A1625493CE87CA1590B5C9D" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_809EFA007006AD35B42F7CA1590DE030" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CommitmentsAndContingenciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_82BA6192EEAEDA64600BE8A998E8F42C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_1708E8941BC1ED046D12E8A998E8B3ED" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_82BA6192EEAEDA64600BE8A998E8F42C" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_1708E8941BC1ED046D12E8A998E8B3ED" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_F23D46C671D639BF2F1FE8A99A3AE55E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F23D46C671D639BF2F1FE8A99A3AE55E" xlink:to="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaap_AssetsCurrentAbstract_6BD75A7F299065F2BCFCE8A99A3B4108" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_AssetsCurrentAbstract_6BD75A7F299065F2BCFCE8A99A3B4108" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_9738B782602568E8786CE8A99A3B34EF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_6BD75A7F299065F2BCFCE8A99A3B4108" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_9738B782602568E8786CE8A99A3B34EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_48F821A3C8840FC27B3DE8A99A3C352F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_6BD75A7F299065F2BCFCE8A99A3B4108" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_48F821A3C8840FC27B3DE8A99A3C352F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_778F55C0EF5F0C466445E8A99A3C2395" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_6BD75A7F299065F2BCFCE8A99A3B4108" xlink:to="loc_us-gaap_InventoryNet_778F55C0EF5F0C466445E8A99A3C2395" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_30A6C9915321C1BE2E5CE8A99A3CFDC7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_6BD75A7F299065F2BCFCE8A99A3B4108" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_30A6C9915321C1BE2E5CE8A99A3CFDC7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_8EBBD07C7506ED0AAB58E8A99A3CFBAD" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_6BD75A7F299065F2BCFCE8A99A3B4108" xlink:to="loc_us-gaap_AssetsCurrent_8EBBD07C7506ED0AAB58E8A99A3CFBAD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_8048005EEB8DD4ED05D5E8A99A3CF634" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_8048005EEB8DD4ED05D5E8A99A3CF634" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_2EB90506D01A3DCFB847E8A99A3CBF99" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_2EB90506D01A3DCFB847E8A99A3CBF99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_C949AAECEB6A52B9A5A9E8A99A3DA92D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_C949AAECEB6A52B9A5A9E8A99A3DA92D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_65A0C68F99584387B82CE8A99A3DCA99" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_Goodwill_65A0C68F99584387B82CE8A99A3DCA99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_F8EE0562EF8CF6F5A5A3E8A99A3DA473" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_F8EE0562EF8CF6F5A5A3E8A99A3DA473" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_F4A6C4B9BFB95B5F4978E8A99A3DAAB5" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_F4A6C4B9BFB95B5F4978E8A99A3DAAB5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_A729CCFA7381C0FFF1D8E8A99A3DC270" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_523E376CE39141DE4C25E8A99A3B7179" xlink:to="loc_us-gaap_Assets_A729CCFA7381C0FFF1D8E8A99A3DC270" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F23D46C671D639BF2F1FE8A99A3AE55E" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_646D7C4595C24593EB72E8A99A3EDDF6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_646D7C4595C24593EB72E8A99A3EDDF6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaap_AccountsPayableCurrent_AAD01C526C6B037E6092E8A99A3E4B3A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_646D7C4595C24593EB72E8A99A3EDDF6" xlink:to="loc_us-gaap_AccountsPayableCurrent_AAD01C526C6B037E6092E8A99A3E4B3A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_3546F150BCAFC5467A4BE8A99A3FECA4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_646D7C4595C24593EB72E8A99A3EDDF6" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_3546F150BCAFC5467A4BE8A99A3FECA4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_8ABD2F2BE67DAD0A77A5E8A99A3F4371" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_646D7C4595C24593EB72E8A99A3EDDF6" xlink:to="loc_us-gaap_LongTermDebtCurrent_8ABD2F2BE67DAD0A77A5E8A99A3F4371" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_803385F479ED2CB95C86E8A99A3F29E1" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_646D7C4595C24593EB72E8A99A3EDDF6" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_803385F479ED2CB95C86E8A99A3F29E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_193C1B013E500DA5E9B8E8A99A3FC732" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_646D7C4595C24593EB72E8A99A3EDDF6" xlink:to="loc_us-gaap_LiabilitiesCurrent_193C1B013E500DA5E9B8E8A99A3FC732" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_4AF237D342C934DF204AE8A99A4004F9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_4AF237D342C934DF204AE8A99A4004F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredRevenueLeasesNetNoncurrent" xlink:label="loc_us-gaap_DeferredRevenueLeasesNetNoncurrent_07DFAC5905F54E2B1BFAE8A99A40C44F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_DeferredRevenueLeasesNetNoncurrent_07DFAC5905F54E2B1BFAE8A99A40C44F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_0E197E003F3562CDD87EE8A99A41C073" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_0E197E003F3562CDD87EE8A99A41C073" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_2701BD7384EC66C25B06E8A99A42E1D5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_2701BD7384EC66C25B06E8A99A42E1D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_3D711063EBD22248836CE8A99A424F68" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_Liabilities_3D711063EBD22248836CE8A99A424F68" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="loc_us-gaap_CommitmentsAndContingencies_0FBAAFE5BBEB6C0A9AD2E8A99A4241A6" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_CommitmentsAndContingencies_0FBAAFE5BBEB6C0A9AD2E8A99A4241A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="loc_us-gaap_StockholdersEquityAbstract_2CB487D732E3D150EE1DE8A99A42927D" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_StockholdersEquityAbstract_2CB487D732E3D150EE1DE8A99A42927D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaap_PreferredStockValue_F69A5277EC0E67F2C8B7E8A99A43B48D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_2CB487D732E3D150EE1DE8A99A42927D" xlink:to="loc_us-gaap_PreferredStockValue_F69A5277EC0E67F2C8B7E8A99A43B48D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_65A024C2797C1AB243B1E8A99A44D114" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_2CB487D732E3D150EE1DE8A99A42927D" xlink:to="loc_us-gaap_CommonStockValue_65A024C2797C1AB243B1E8A99A44D114" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_A431C4B2DD4B381D3CDEE8A99A44DF07" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_2CB487D732E3D150EE1DE8A99A42927D" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_A431C4B2DD4B381D3CDEE8A99A44DF07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_B5F1D25E856F291F382DE8A99A445E8D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_2CB487D732E3D150EE1DE8A99A42927D" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_B5F1D25E856F291F382DE8A99A445E8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_6E400A5070B4E3E215FBE8A99A449C39" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_2CB487D732E3D150EE1DE8A99A42927D" xlink:to="loc_us-gaap_StockholdersEquity_6E400A5070B4E3E215FBE8A99A449C39" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_34615905AD81583757C7E8A99A44E795" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_025EAD584B9C0A0AD525E8A99A3EEBFC" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_34615905AD81583757C7E8A99A44E795" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_2370C8D76461D7B6DFCFE8A99A2AE25F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_2370C8D76461D7B6DFCFE8A99A2AE25F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_6952D2D8F96E82D6B7CFE8A99A2ADCA8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_6952D2D8F96E82D6B7CFE8A99A2ADCA8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PreferredStockSharesIssued" xlink:label="loc_us-gaap_PreferredStockSharesIssued_B335A4AF07B082088E05E8A99A2A90CF" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_PreferredStockSharesIssued_B335A4AF07B082088E05E8A99A2A90CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_C25EAC782898EDDAB9FDE8A99A2AAAC9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_C25EAC782898EDDAB9FDE8A99A2AAAC9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_8BA951A2AADF2897A755E8A99A2B65D1" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_8BA951A2AADF2897A755E8A99A2B65D1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_20D49678ABD2A9F5679AE8A99A2B190F" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_20D49678ABD2A9F5679AE8A99A2B190F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_4F9C60B68277D68B69F6E8A99A2B2F6F" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_CommonStockSharesIssued_4F9C60B68277D68B69F6E8A99A2B2F6F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_F0B04284BF1D27C88C9AE8A99A2B9AC8" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_6FA92E665D67D6B06048E8A99A2A7C56" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_F0B04284BF1D27C88C9AE8A99A2B9AC8" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ConsolidatedStatementsOfCashFlows" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_CF42D3BB677BA0C315BC64AA444D3490" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_CF42D3BB677BA0C315BC64AA444D3490" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_312CEDA05520089E729F64AA444E244B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_CF42D3BB677BA0C315BC64AA444D3490" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_312CEDA05520089E729F64AA444E244B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_CF42D3BB677BA0C315BC64AA444D3490" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_1EAA95020747D9535BB764AA444EA29F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_1EAA95020747D9535BB764AA444EA29F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xlink:label="loc_us-gaap_GainLossOnSaleOfPropertyPlantEquipment_850895D5CE8C4347E1BF64AA444E90F3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:to="loc_us-gaap_GainLossOnSaleOfPropertyPlantEquipment_850895D5CE8C4347E1BF64AA444E90F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_3DCBF2D17C5D51EF2F8864AA444F26B6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:to="loc_us-gaap_ShareBasedCompensation_3DCBF2D17C5D51EF2F8864AA444F26B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherOperatingActivitiesCashFlowStatement" xlink:label="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_BC30017CF586D0108E8D64AA444FED71" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:to="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_BC30017CF586D0108E8D64AA444FED71" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_811CF34245A1A825F4D364AA444F6192" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_811CF34245A1A825F4D364AA444F6192" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtinstrumentEndofTermPaymentInterestAmountandPrepaymentPenalty" xlink:label="loc_vcyt_DebtinstrumentEndofTermPaymentInterestAmountandPrepaymentPenalty_E3038F6CC07030F43D8F64AA444F2345" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_A754C6D8D1921665035864AA444E737E" xlink:to="loc_vcyt_DebtinstrumentEndofTermPaymentInterestAmountandPrepaymentPenalty_E3038F6CC07030F43D8F64AA444F2345" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_CF42D3BB677BA0C315BC64AA444D3490" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_51D274E7851D9B7DC9F064AA444FD854" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_51D274E7851D9B7DC9F064AA444FD854" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_1FD39841AFC649480D6864AA44501826" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_1FD39841AFC649480D6864AA44501826" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_5D754E688EDDFC1F67B764AA44500B04" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_5D754E688EDDFC1F67B764AA44500B04" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_IncreaseDecreaseinOperatingLeaseAssetsandLiabilities" xlink:label="loc_vcyt_IncreaseDecreaseinOperatingLeaseAssetsandLiabilities_1FEF633EDE66B83BBEC664AA4450DA3B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:to="loc_vcyt_IncreaseDecreaseinOperatingLeaseAssetsandLiabilities_1FEF633EDE66B83BBEC664AA4450DA3B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_9E44A7A856A54F162FBE64AA4450817C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_9E44A7A856A54F162FBE64AA4450817C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_5E418EFECC1A3E502D1164AA4450D562" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_5E418EFECC1A3E502D1164AA4450D562" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent" xlink:label="loc_vcyt_IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent_8C98D64785527F31E70D64AA4455A5E3" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_15F8F9A2CD2BB4DFBB8A64AA444F418A" xlink:to="loc_vcyt_IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent_8C98D64785527F31E70D64AA4455A5E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_B9CFF25AE8A8E0B56ACE64AA4455DCF4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_CF42D3BB677BA0C315BC64AA444D3490" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_B9CFF25AE8A8E0B56ACE64AA4455DCF4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_79FBEE9DFEA4C12098C864AA4455AA39" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_79FBEE9DFEA4C12098C864AA4455AA39" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_9C324389358563743B7264AA4455844A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_79FBEE9DFEA4C12098C864AA4455AA39" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_9C324389358563743B7264AA4455844A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_5AF3CC98CC98A6EB4C3F64AA445593D5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_79FBEE9DFEA4C12098C864AA4455AA39" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_5AF3CC98CC98A6EB4C3F64AA445593D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_D43DB4BE2EF25EB9F1FA64AA4456E078" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_79FBEE9DFEA4C12098C864AA4455AA39" xlink:to="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_D43DB4BE2EF25EB9F1FA64AA4456E078" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_8D97388B0FC415F6BAE564AA4456874A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_79FBEE9DFEA4C12098C864AA4455AA39" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_8D97388B0FC415F6BAE564AA4456874A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_56A39EC6BF4318FDF43C64AA44567866" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_56A39EC6BF4318FDF43C64AA44567866" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromIssuanceInitialPublicOffering" xlink:label="loc_us-gaap_ProceedsFromIssuanceInitialPublicOffering_4342DF15F9CF6D81D66464AA44566D54" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_us-gaap_ProceedsFromIssuanceInitialPublicOffering_4342DF15F9CF6D81D66464AA44566D54" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_DC8DCA99B72724450B7E64AA44577BDC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_DC8DCA99B72724450B7E64AA44577BDC" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_PaymentOfEndOfTermObligation" xlink:label="loc_vcyt_PaymentOfEndOfTermObligation_D0B7149E75EC43421D6C64AA44572F1A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_vcyt_PaymentOfEndOfTermObligation_D0B7149E75EC43421D6C64AA44572F1A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromLegalSettlements" xlink:label="loc_us-gaap_ProceedsFromLegalSettlements_4B0984DBFBBFE43C3E0164AA44575335" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_us-gaap_ProceedsFromLegalSettlements_4B0984DBFBBFE43C3E0164AA44575335" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfLongTermCapitalLeaseObligations" xlink:label="loc_us-gaap_RepaymentsOfLongTermCapitalLeaseObligations_11003AA480CC7163C56E64AA44576235" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_us-gaap_RepaymentsOfLongTermCapitalLeaseObligations_11003AA480CC7163C56E64AA44576235" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_5F9260C0AEC0881E971864AA4457E709" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_5F9260C0AEC0881E971864AA4457E709" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_2662299CBF951AD0778F64AA445759ED" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_112FB1874EA33885D91564AA44562E12" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_2662299CBF951AD0778F64AA445759ED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_C0A8C7569FF47EC0E15664AA4458D866" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_C0A8C7569FF47EC0E15664AA4458D866" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7CC025697BD5A49A8F1B64AA44580D70" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_7CC025697BD5A49A8F1B64AA44580D70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_260DC3DA86A36853A64A64AA44584559" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_260DC3DA86A36853A64A64AA44584559" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract" xlink:label="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_956B5A18C8B5DC93D31664AA44586BBC" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_956B5A18C8B5DC93D31664AA44586BBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_9AF7A11C67487189368A64AA4458FDC7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_956B5A18C8B5DC93D31664AA44586BBC" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_9AF7A11C67487189368A64AA4458FDC7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable_175D2071922479D2A86864AA4459B23B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_956B5A18C8B5DC93D31664AA44586BBC" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable_175D2071922479D2A86864AA4459B23B" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NoncashorPartNoncashAcquisitionDeferredPurchaseConsideration" xlink:label="loc_vcyt_NoncashorPartNoncashAcquisitionDeferredPurchaseConsideration_857FD9788F5347949EA964AA4459667C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_956B5A18C8B5DC93D31664AA44586BBC" xlink:to="loc_vcyt_NoncashorPartNoncashAcquisitionDeferredPurchaseConsideration_857FD9788F5347949EA964AA4459667C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CapitalExpendituresIncurredButNotYetPaid" xlink:label="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_EDD30213BAC475802B5564AA445948C4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_956B5A18C8B5DC93D31664AA44586BBC" xlink:to="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_EDD30213BAC475802B5564AA445948C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_B31971D16BA70544F0A664AA4459BBBC" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_B31971D16BA70544F0A664AA4459BBBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestPaidNet" xlink:label="loc_us-gaap_InterestPaidNet_6956A03647BA9F106BEC64AA4459816D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_B31971D16BA70544F0A664AA4459BBBC" xlink:to="loc_us-gaap_InterestPaidNet_6956A03647BA9F106BEC64AA4459816D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxesPaid" xlink:label="loc_us-gaap_IncomeTaxesPaid_D44B1448AB8ABB8BC56E64AA445A28B9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_B31971D16BA70544F0A664AA4459BBBC" xlink:to="loc_us-gaap_IncomeTaxesPaid_D44B1448AB8ABB8BC56E64AA445A28B9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_7E959849F86E68B5D1E764AA445A6C5F" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_7E959849F86E68B5D1E764AA445A6C5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_CB18A0085E488DEA0F5D64AA445A2042" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_CB18A0085E488DEA0F5D64AA445A2042" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4225B3B76D977F7568D264AA445AD6BC" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_55937A635D7C6616D74664AA444D871C" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4225B3B76D977F7568D264AA445AD6BC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_B88C8DDECDA09E42FC5549ADE1F69593" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_C47349A8D613C19D998C49ADE1F6138C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_B88C8DDECDA09E42FC5549ADE1F69593" xlink:to="loc_us-gaap_StatementTable_C47349A8D613C19D998C49ADE1F6138C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_15173D4179CC14F42DC449C8B5C3EEB4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_C47349A8D613C19D998C49ADE1F6138C" xlink:to="loc_srt_ProductOrServiceAxis_15173D4179CC14F42DC449C8B5C3EEB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_D97BD656A9A7A92E036749C92958406C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_15173D4179CC14F42DC449C8B5C3EEB4" xlink:to="loc_srt_ProductsAndServicesDomain_D97BD656A9A7A92E036749C92958406C" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_TestingMember" xlink:label="loc_vcyt_TestingMember_84C15BE198D7D3178B6149ADE1F7AF46" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_D97BD656A9A7A92E036749C92958406C" xlink:to="loc_vcyt_TestingMember_84C15BE198D7D3178B6149ADE1F7AF46" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductMember" xlink:label="loc_us-gaap_ProductMember_E0751FBBD331AA70A6A949ADE1F79EEE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_D97BD656A9A7A92E036749C92958406C" xlink:to="loc_us-gaap_ProductMember_E0751FBBD331AA70A6A949ADE1F79EEE" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_BiopharmaceuticalMember" xlink:label="loc_vcyt_BiopharmaceuticalMember_37DA8CA5EFB2FA988D0749ADE1F8C0FF" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_D97BD656A9A7A92E036749C92958406C" xlink:to="loc_vcyt_BiopharmaceuticalMember_37DA8CA5EFB2FA988D0749ADE1F8C0FF" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_CollaborationMember" xlink:label="loc_vcyt_CollaborationMember_83A774CDED0720D7FA8B49ADE1F810FE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_D97BD656A9A7A92E036749C92958406C" xlink:to="loc_vcyt_CollaborationMember_83A774CDED0720D7FA8B49ADE1F810FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_C47349A8D613C19D998C49ADE1F6138C" xlink:to="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5D437D982090827C716A49ADE1F82018" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5D437D982090827C716A49ADE1F82018" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaap_CostOfRevenue_53E32EEA96E48E58B15949ADE1F8F232" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:to="loc_us-gaap_CostOfRevenue_53E32EEA96E48E58B15949ADE1F8F232" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostDirectMaterial" xlink:label="loc_us-gaap_CostDirectMaterial_6189FC80DC98CD1D68A249ADE1F9F035" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:to="loc_us-gaap_CostDirectMaterial_6189FC80DC98CD1D68A249ADE1F9F035" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_57F8A14D7F927EF9DD9F49ADE1F95899" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_57F8A14D7F927EF9DD9F49ADE1F95899" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SellingAndMarketingExpense" xlink:label="loc_us-gaap_SellingAndMarketingExpense_F2666963E369188D982649ADE1F926BD" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:to="loc_us-gaap_SellingAndMarketingExpense_F2666963E369188D982649ADE1F926BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_BCF5DDA7BC9AEAF63B1249ADE1F90245" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_BCF5DDA7BC9AEAF63B1249ADE1F90245" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentForAmortization" xlink:label="loc_us-gaap_AdjustmentForAmortization_846E7AE00D2B23EF0E9D49ADE1F90FAB" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:to="loc_us-gaap_AdjustmentForAmortization_846E7AE00D2B23EF0E9D49ADE1F90FAB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostsAndExpenses" xlink:label="loc_us-gaap_CostsAndExpenses_6845F698DB293B77552A49ADE1F98300" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D84FA359CFB800C1942549ADE1F8B809" xlink:to="loc_us-gaap_CostsAndExpenses_6845F698DB293B77552A49ADE1F98300" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_51E39F233D0B17A1C51749ADE1FAA6EB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_OperatingIncomeLoss_51E39F233D0B17A1C51749ADE1FAA6EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_5A0529158B43302D578049ADE1FA1346" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_InterestExpense_5A0529158B43302D578049ADE1FA1346" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_9FDC4A14308281ADE5FB49ADE1FA4D18" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_9FDC4A14308281ADE5FB49ADE1FA4D18" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_AB15E8CC4370EFE5D09149ADE1FAB55B" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_AB15E8CC4370EFE5D09149ADE1FAB55B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_1D79B154F68EA31DBF1649ADE1FA61C1" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_1D79B154F68EA31DBF1649ADE1FA61C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_9263DE0F5A2C4EA8AA1A49ADE1FA64B3" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_9263DE0F5A2C4EA8AA1A49ADE1FA64B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_8C690288FE4154F6EE2649ADE1FB2475" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_34AAE5B8AFCF560F2ABA49ADE1F809B0" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_8C690288FE4154F6EE2649ADE1FB2475" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ConsolidatedStatementsOfStockholdersEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_A020364D37A973FD201FED4F9E6B9CAE" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_D08961729B6619265C70ED4F9E6BD81D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_A020364D37A973FD201FED4F9E6B9CAE" xlink:to="loc_us-gaap_StatementTable_D08961729B6619265C70ED4F9E6BD81D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_EF0B2CD6FCB02371E328ED4F9E6C59AE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_D08961729B6619265C70ED4F9E6BD81D" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_EF0B2CD6FCB02371E328ED4F9E6C59AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_3B75644AD0890856B3A7ED4F9E6C14BC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_EF0B2CD6FCB02371E328ED4F9E6C59AE" xlink:to="loc_us-gaap_EquityComponentDomain_3B75644AD0890856B3A7ED4F9E6C14BC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_6D61035D8D021CE9C890ED4F9E6FD7F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_3B75644AD0890856B3A7ED4F9E6C14BC" xlink:to="loc_us-gaap_CommonStockMember_6D61035D8D021CE9C890ED4F9E6FD7F4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_C425C66568119F0F9E5BED4F9E70D32A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_3B75644AD0890856B3A7ED4F9E6C14BC" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_C425C66568119F0F9E5BED4F9E70D32A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_37FDA7DC60713128CE4EED4F9E708E81" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_3B75644AD0890856B3A7ED4F9E6C14BC" xlink:to="loc_us-gaap_RetainedEarningsMember_37FDA7DC60713128CE4EED4F9E708E81" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_817F3CECD48DA89AA5F7ED4F9E717EEF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_D08961729B6619265C70ED4F9E6BD81D" xlink:to="loc_us-gaap_StatementLineItems_817F3CECD48DA89AA5F7ED4F9E717EEF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_817F3CECD48DA89AA5F7ED4F9E717EEF" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_21A4C31C854BD4CCCD5DED4F9E71BA8A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_StockholdersEquity_21A4C31C854BD4CCCD5DED4F9E71BA8A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharesOutstanding" xlink:label="loc_us-gaap_SharesOutstanding_A7F14CCFAC317C7688FEED4F9E7256F1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_SharesOutstanding_A7F14CCFAC317C7688FEED4F9E7256F1" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardValueOptionsandNonOptionEquityInstrumentsExercisesinPeriod" xlink:label="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardValueOptionsandNonOptionEquityInstrumentsExercisesinPeriod_D996B8DC07EB3D7C0DCBED4F9E725674" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardValueOptionsandNonOptionEquityInstrumentsExercisesinPeriod_D996B8DC07EB3D7C0DCBED4F9E725674" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsandNonOptionEquityInstrumentsExercisesinPeriod" xlink:label="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsandNonOptionEquityInstrumentsExercisesinPeriod_FAB66C47467BE8DAFB6AED4F9E73CEA3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsandNonOptionEquityInstrumentsExercisesinPeriod_FAB66C47467BE8DAFB6AED4F9E73CEA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_231F65D9E19D2A6F923EED4F9E73966B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_231F65D9E19D2A6F923EED4F9E73966B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_BA9EB59305B14B78D686ED4F9E739910" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_BA9EB59305B14B78D686ED4F9E739910" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_StockIssuedAndSoldDuringPeriodValueInPrivatePlacement" xlink:label="loc_vcyt_StockIssuedAndSoldDuringPeriodValueInPrivatePlacement_3EB86804403BEFE2A6D1ED4F9E73A5F5" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_StockIssuedAndSoldDuringPeriodValueInPrivatePlacement_3EB86804403BEFE2A6D1ED4F9E73A5F5" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_StockIssuedAndSoldDuringPeriodSharesInPrivatePlacement" xlink:label="loc_vcyt_StockIssuedAndSoldDuringPeriodSharesInPrivatePlacement_379E8CEAD284FEC5716EED4F9E74CAED" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_StockIssuedAndSoldDuringPeriodSharesInPrivatePlacement_379E8CEAD284FEC5716EED4F9E74CAED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueAcquisitions" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueAcquisitions_2CFB46C540FCDFCD5809ED4F9E749362" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueAcquisitions_2CFB46C540FCDFCD5809ED4F9E749362" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesAcquisitions" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesAcquisitions_AC6301F4571E2DF656BEED4F9E7462E0" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesAcquisitions_AC6301F4571E2DF656BEED4F9E7462E0" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployee" xlink:label="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployee_D821B18C9871574894C8ED4F9E748182" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployee_D821B18C9871574894C8ED4F9E748182" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationNonEmployee" xlink:label="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationNonEmployee_5E44427D9327375B3598ED4F9E75E3B5" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationNonEmployee_5E44427D9327375B3598ED4F9E75E3B5" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationESPP" xlink:label="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationESPP_78A28A59B2E862C124DBED4F9E75D4F9" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationESPP_78A28A59B2E862C124DBED4F9E75D4F9" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_LegalSettlementRegardingShortSwingProfitsNetOfTax" xlink:label="loc_vcyt_LegalSettlementRegardingShortSwingProfitsNetOfTax_2781501F55EEB74F1E39ED4F9E753705" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_vcyt_LegalSettlementRegardingShortSwingProfitsNetOfTax_2781501F55EEB74F1E39ED4F9E753705" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_390C3BC26F15B9DD5331ED4F9E75CCC1" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_390C3BC26F15B9DD5331ED4F9E75CCC1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_A0DF4BC510AB4964AA05ED4F9E761FE5" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_A0DF4BC510AB4964AA05ED4F9E761FE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_902CBBA60184C70CF56CED4F9E769AAA" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_StockholdersEquity_902CBBA60184C70CF56CED4F9E769AAA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharesOutstanding" xlink:label="loc_us-gaap_SharesOutstanding_DC6CDCDDD6F5FDFEEE60ED4F9E760D02" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_BA3BE23213A05AD14286ED4F9E711416" xlink:to="loc_us-gaap_SharesOutstanding_DC6CDCDDD6F5FDFEEE60ED4F9E760D02" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ConsolidatedStatementsOfStockholdersEquityParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_B25244485B2811DCF598E8A99A0561C9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_2A2E228154EFE5CB19DBE8A99A055BD4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_B25244485B2811DCF598E8A99A0561C9" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_2A2E228154EFE5CB19DBE8A99A055BD4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CoverAbstract" xlink:label="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:type="locator" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_C628D235859FA70EC3C6363F734E5786" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_DocumentType_C628D235859FA70EC3C6363F734E5786" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentAnnualReport" xlink:label="loc_dei_DocumentAnnualReport_96FDB9DB897B1EC191E8363F734EC4FA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_DocumentAnnualReport_96FDB9DB897B1EC191E8363F734EC4FA" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_B912964E154735CA0888363F734ED0D6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_DocumentPeriodEndDate_B912964E154735CA0888363F734ED0D6" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentTransitionReport" xlink:label="loc_dei_DocumentTransitionReport_FDB4F2881A25B70AA61A363F734E3384" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_DocumentTransitionReport_FDB4F2881A25B70AA61A363F734E3384" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFileNumber" xlink:label="loc_dei_EntityFileNumber_ED52842333326D26FC16363F734E6693" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityFileNumber_ED52842333326D26FC16363F734E6693" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_180ABC74A76BD47B1E3A363F734E962E" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityRegistrantName_180ABC74A76BD47B1E3A363F734E962E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="loc_dei_EntityIncorporationStateCountryCode_B08A7513D14910950337363F734E3024" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityIncorporationStateCountryCode_B08A7513D14910950337363F734E3024" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:label="loc_dei_EntityTaxIdentificationNumber_09F8B1AD7E19F3B3FB05363F734E320C" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityTaxIdentificationNumber_09F8B1AD7E19F3B3FB05363F734E320C" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine1" xlink:label="loc_dei_EntityAddressAddressLine1_FFFA499C9B828BF7731E363F734EEAE0" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityAddressAddressLine1_FFFA499C9B828BF7731E363F734EEAE0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressAddressLine2" xlink:label="loc_dei_EntityAddressAddressLine2_3F2B07C95664ECAA716E363F734E02DD" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityAddressAddressLine2_3F2B07C95664ECAA716E363F734E02DD" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressCityOrTown" xlink:label="loc_dei_EntityAddressCityOrTown_99191D31A7064302A2A1363F734E179E" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityAddressCityOrTown_99191D31A7064302A2A1363F734E179E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:label="loc_dei_EntityAddressStateOrProvince_454F5F7B8D078D3A5622363F734E75B3" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityAddressStateOrProvince_454F5F7B8D078D3A5622363F734E75B3" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:label="loc_dei_EntityAddressPostalZipCode_400F58792F756CE808B7363F734E152E" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityAddressPostalZipCode_400F58792F756CE808B7363F734E152E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CityAreaCode" xlink:label="loc_dei_CityAreaCode_6E787466108DAEAE94D6363F734E1925" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_CityAreaCode_6E787466108DAEAE94D6363F734E1925" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LocalPhoneNumber" xlink:label="loc_dei_LocalPhoneNumber_30D1AB8D667B6C8B5F5E363F734E4D4E" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_LocalPhoneNumber_30D1AB8D667B6C8B5F5E363F734E4D4E" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_Security12bTitle" xlink:label="loc_dei_Security12bTitle_F7F56AF7FCFE5DCA629E363F734E1072" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_Security12bTitle_F7F56AF7FCFE5DCA629E363F734E1072" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_TradingSymbol" xlink:label="loc_dei_TradingSymbol_9B8FFB495D147251A373363F734E2B19" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_TradingSymbol_9B8FFB495D147251A373363F734E2B19" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_SecurityExchangeName" xlink:label="loc_dei_SecurityExchangeName_E722627F97AF7F0BA26D363F734E2778" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_SecurityExchangeName_E722627F97AF7F0BA26D363F734E2778" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="loc_dei_EntityWellKnownSeasonedIssuer_D5952F0236F1AA2CF3EF363F734E7315" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityWellKnownSeasonedIssuer_D5952F0236F1AA2CF3EF363F734E7315" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityVoluntaryFilers" xlink:label="loc_dei_EntityVoluntaryFilers_48B8AA21B6BA009C62A0363F734E1F64" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityVoluntaryFilers_48B8AA21B6BA009C62A0363F734E1F64" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_dei_EntityCurrentReportingStatus_7F24DA52B5CA7F85BC1E363F734E1452" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityCurrentReportingStatus_7F24DA52B5CA7F85BC1E363F734E1452" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityInteractiveDataCurrent" xlink:label="loc_dei_EntityInteractiveDataCurrent_72BE7F8C399E8E65BFBE363F734E8B56" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityInteractiveDataCurrent_72BE7F8C399E8E65BFBE363F734E8B56" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityFilerCategory" xlink:label="loc_dei_EntityFilerCategory_846C73A1B84544405773363F734EA7EE" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityFilerCategory_846C73A1B84544405773363F734EA7EE" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntitySmallBusiness" xlink:label="loc_dei_EntitySmallBusiness_1197FD8D2AC5A45BE1EA363F734EB349" xlink:type="locator" />
    <link:presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntitySmallBusiness_1197FD8D2AC5A45BE1EA363F734EB349" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_dei_EntityEmergingGrowthCompany_7BBCBD03C6D8BB13816E363F734E5C72" xlink:type="locator" />
    <link:presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityEmergingGrowthCompany_7BBCBD03C6D8BB13816E363F734E5C72" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityShellCompany" xlink:label="loc_dei_EntityShellCompany_123F13D1B8640D21F3CF363F734EE7B6" xlink:type="locator" />
    <link:presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityShellCompany_123F13D1B8640D21F3CF363F734EE7B6" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityPublicFloat" xlink:label="loc_dei_EntityPublicFloat_999622F7C4DE76FC67C3363F734EE661" xlink:type="locator" />
    <link:presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityPublicFloat_999622F7C4DE76FC67C3363F734EE661" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_D5A4D6B5D2657C51780E363F734E08E3" xlink:type="locator" />
    <link:presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_D5A4D6B5D2657C51780E363F734E08E3" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentsIncorporatedByReferenceTextBlock" xlink:label="loc_dei_DocumentsIncorporatedByReferenceTextBlock_101A66F1A54E8E6B9599363F734EC205" xlink:type="locator" />
    <link:presentationArc order="29" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_DocumentsIncorporatedByReferenceTextBlock_101A66F1A54E8E6B9599363F734EC205" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_F9663DFD797B344EC43B363F734E0ED2" xlink:type="locator" />
    <link:presentationArc order="30" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_EntityCentralIndexKey_F9663DFD797B344EC43B363F734E0ED2" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_6AE0DC4E84C9841FCD3D363F734E9DF3" xlink:type="locator" />
    <link:presentationArc order="31" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_AmendmentFlag_6AE0DC4E84C9841FCD3D363F734E9DF3" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_dei_CurrentFiscalYearEndDate_31817F0C4AA6F4F21E7C363F734EEFE5" xlink:type="locator" />
    <link:presentationArc order="32" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_CurrentFiscalYearEndDate_31817F0C4AA6F4F21E7C363F734EEFE5" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_dei_DocumentFiscalYearFocus_34D69DB405554F3537F5363F734ECC91" xlink:type="locator" />
    <link:presentationArc order="33" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_DocumentFiscalYearFocus_34D69DB405554F3537F5363F734ECC91" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_dei_DocumentFiscalPeriodFocus_E6C477F93F8280E2A4B3363F734E5723" xlink:type="locator" />
    <link:presentationArc order="34" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_41B82AF46163953BE166363F734EBCA0" xlink:to="loc_dei_DocumentFiscalPeriodFocus_E6C477F93F8280E2A4B3363F734E5723" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/Debt" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_6100A3E00FAA34C04666E8A998BE625D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_DDBF312B9CAAD7EAF5DCE8A998BE54B3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_6100A3E00FAA34C04666E8A998BE625D" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_DDBF312B9CAAD7EAF5DCE8A998BE54B3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtCreditAgreementDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_8194580241027892BE00E8A9983D1AEE" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_7E4A410A7455975D8EE7E8A9983EB815" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_8194580241027892BE00E8A9983D1AEE" xlink:to="loc_us-gaap_DebtInstrumentTable_7E4A410A7455975D8EE7E8A9983EB815" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_DB84B50316606E67344CE8A9983F8F91" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7E4A410A7455975D8EE7E8A9983EB815" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_DB84B50316606E67344CE8A9983F8F91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_84677FF1C8D837CD0598E8A99841E2FB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_DB84B50316606E67344CE8A9983F8F91" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_84677FF1C8D837CD0598E8A99841E2FB" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_VisiumMember" xlink:label="loc_vcyt_VisiumMember_BDD69FA374A5C5FFB751E8A998421F87" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_84677FF1C8D837CD0598E8A99841E2FB" xlink:to="loc_vcyt_VisiumMember_BDD69FA374A5C5FFB751E8A998421F87" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_E05262C194FCAA8D133EE8A99846F755" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7E4A410A7455975D8EE7E8A9983EB815" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_E05262C194FCAA8D133EE8A99846F755" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_9ADE748A5AEB0E211C01E8A99846B443" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_E05262C194FCAA8D133EE8A99846F755" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_9ADE748A5AEB0E211C01E8A99846B443" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="loc_us-gaap_LineOfCreditMember_830AD92832610A6A3D6EE8A99848F90B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_9ADE748A5AEB0E211C01E8A99846B443" xlink:to="loc_us-gaap_LineOfCreditMember_830AD92832610A6A3D6EE8A99848F90B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_AD25F9490F44F439BAA2E8A99849C776" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7E4A410A7455975D8EE7E8A9983EB815" xlink:to="loc_us-gaap_DebtInstrumentAxis_AD25F9490F44F439BAA2E8A99849C776" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_8A1673218CCE83F7CAA2E8A998494E4A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_AD25F9490F44F439BAA2E8A99849C776" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_8A1673218CCE83F7CAA2E8A998494E4A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_InitialTermLoanMember" xlink:label="loc_vcyt_InitialTermLoanMember_BB1FC55A21DA6E76898FE8A9984A4561" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_8A1673218CCE83F7CAA2E8A998494E4A" xlink:to="loc_vcyt_InitialTermLoanMember_BB1FC55A21DA6E76898FE8A9984A4561" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7E4A410A7455975D8EE7E8A9983EB815" xlink:to="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NumberOfTermLoans" xlink:label="loc_vcyt_NumberOfTermLoans_08496F483C8306D38AD8E8A9984B2465" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_vcyt_NumberOfTermLoans_08496F483C8306D38AD8E8A9984B2465" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_8A5D322063A227CF978AE8A9984F6BFD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_8A5D322063A227CF978AE8A9984F6BFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromLinesOfCredit" xlink:label="loc_us-gaap_ProceedsFromLinesOfCredit_F5D0BCDC567E9B2F82BBE8A998505793" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_us-gaap_ProceedsFromLinesOfCredit_F5D0BCDC567E9B2F82BBE8A998505793" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_720D7CF81BED363DBD2EE8A9985124A7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_720D7CF81BED363DBD2EE8A9985124A7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_31CE2DA7465962A6112BE8A99851ED73" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_31CE2DA7465962A6112BE8A99851ED73" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtInstrumentNumberOfInstallments" xlink:label="loc_vcyt_DebtInstrumentNumberOfInstallments_C65D5B4F336105B9C442E8A99852A1CD" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_vcyt_DebtInstrumentNumberOfInstallments_C65D5B4F336105B9C442E8A99852A1CD" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_TermOfDebtWithEqualQuarterlyInstallments" xlink:label="loc_vcyt_TermOfDebtWithEqualQuarterlyInstallments_5E76B8AE56057982CAC4E8A998537561" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_vcyt_TermOfDebtWithEqualQuarterlyInstallments_5E76B8AE56057982CAC4E8A998537561" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodOne" xlink:label="loc_vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodOne_60DD378C8C68ACD8E05BE8A998559561" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodOne_60DD378C8C68ACD8E05BE8A998559561" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtInstrumentFixedRatePercentagePaidInCash" xlink:label="loc_vcyt_DebtInstrumentFixedRatePercentagePaidInCash_09640B617F4BECF17736E8A99855A95B" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_vcyt_DebtInstrumentFixedRatePercentagePaidInCash_09640B617F4BECF17736E8A99855A95B" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtInstrumentInterestPaidInKindPercentage" xlink:label="loc_vcyt_DebtInstrumentInterestPaidInKindPercentage_2E601B30A8D692AB0C83E8A99856BA05" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_vcyt_DebtInstrumentInterestPaidInKindPercentage_2E601B30A8D692AB0C83E8A99856BA05" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaidInKindInterest" xlink:label="loc_us-gaap_PaidInKindInterest_BF3379386BEDE8F9A1CDE8A998567412" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_us-gaap_PaidInKindInterest_BF3379386BEDE8F9A1CDE8A998567412" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_PaymentOfEndOfTermObligation" xlink:label="loc_vcyt_PaymentOfEndOfTermObligation_E3F2F84948D9316F9D5DE8A998560911" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7624D9A59D07EB2E9FAFE8A9984B4CC9" xlink:to="loc_vcyt_PaymentOfEndOfTermObligation_E3F2F84948D9316F9D5DE8A998560911" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtInterestExpenseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_56DEC3C550A4B7077B785DDACB6F2F7E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestExpenseDebtExcludingAmortization" xlink:label="loc_us-gaap_InterestExpenseDebtExcludingAmortization_F48CD0A6D2F5652215865DDACB7174D4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_56DEC3C550A4B7077B785DDACB6F2F7E" xlink:to="loc_us-gaap_InterestExpenseDebtExcludingAmortization_F48CD0A6D2F5652215865DDACB7174D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfDebtDiscountPremium" xlink:label="loc_us-gaap_AmortizationOfDebtDiscountPremium_3F553AB351A41A64DAE05DDACB71C54F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_56DEC3C550A4B7077B785DDACB6F2F7E" xlink:to="loc_us-gaap_AmortizationOfDebtDiscountPremium_3F553AB351A41A64DAE05DDACB71C54F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtInstrumentEndOfTermInterestObligationAmount" xlink:label="loc_vcyt_DebtInstrumentEndOfTermInterestObligationAmount_5828464E1FF7C1F8BC505DDACB7138B9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_56DEC3C550A4B7077B785DDACB6F2F7E" xlink:to="loc_vcyt_DebtInstrumentEndOfTermInterestObligationAmount_5828464E1FF7C1F8BC505DDACB7138B9" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_PrepaymentPenalty" xlink:label="loc_vcyt_PrepaymentPenalty_44AF46EBE556BDA4A6385DDACB71AE34" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_56DEC3C550A4B7077B785DDACB6F2F7E" xlink:to="loc_vcyt_PrepaymentPenalty_44AF46EBE556BDA4A6385DDACB71AE34" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseInterestExpense" xlink:label="loc_us-gaap_FinanceLeaseInterestExpense_4EFB488A1B709264C5015DDACB72581E" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_56DEC3C550A4B7077B785DDACB6F2F7E" xlink:to="loc_us-gaap_FinanceLeaseInterestExpense_4EFB488A1B709264C5015DDACB72581E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestExpenseDebt" xlink:label="loc_us-gaap_InterestExpenseDebt_DB2BC34CE38E52CB52905DDACB721DBC" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_56DEC3C550A4B7077B785DDACB6F2F7E" xlink:to="loc_us-gaap_InterestExpenseDebt_DB2BC34CE38E52CB52905DDACB721DBC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtLoanAndSecurityAgreementDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_A1CAE39FBE5274164AA9402FCF3537B1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityTable" xlink:label="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_A1CAE39FBE5274164AA9402FCF3537B1" xlink:to="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtPrepaymentTrancheAxis" xlink:label="loc_vcyt_DebtPrepaymentTrancheAxis_3C201686CBF0F6DB4F34402FCF358ECF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:to="loc_vcyt_DebtPrepaymentTrancheAxis_3C201686CBF0F6DB4F34402FCF358ECF" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtPaymentTrancheDomain" xlink:label="loc_vcyt_DebtPaymentTrancheDomain_AE0871D9960D84850996402FCF36FB96" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPrepaymentTrancheAxis_3C201686CBF0F6DB4F34402FCF358ECF" xlink:to="loc_vcyt_DebtPaymentTrancheDomain_AE0871D9960D84850996402FCF36FB96" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtPrepaymentTrancheOneMember" xlink:label="loc_vcyt_DebtPrepaymentTrancheOneMember_7923C5189C22BCB2E54F402FCF36BD1F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPaymentTrancheDomain_AE0871D9960D84850996402FCF36FB96" xlink:to="loc_vcyt_DebtPrepaymentTrancheOneMember_7923C5189C22BCB2E54F402FCF36BD1F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtPrepaymentTrancheTwoMember" xlink:label="loc_vcyt_DebtPrepaymentTrancheTwoMember_646A9DA5F97D2DF98DFD402FCF369634" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPaymentTrancheDomain_AE0871D9960D84850996402FCF36FB96" xlink:to="loc_vcyt_DebtPrepaymentTrancheTwoMember_646A9DA5F97D2DF98DFD402FCF369634" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtPrepaymentTrancheThreeMember" xlink:label="loc_vcyt_DebtPrepaymentTrancheThreeMember_41B5D4675C99F277B6EA402FCF368868" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPaymentTrancheDomain_AE0871D9960D84850996402FCF36FB96" xlink:to="loc_vcyt_DebtPrepaymentTrancheThreeMember_41B5D4675C99F277B6EA402FCF368868" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_B71516271E573454473F402FCF3607D9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:to="loc_srt_RangeAxis_B71516271E573454473F402FCF3607D9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_466CC1DA23A804CC1440402FCF37AE63" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_B71516271E573454473F402FCF3607D9" xlink:to="loc_srt_RangeMember_466CC1DA23A804CC1440402FCF37AE63" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_79CCC16D314AE1356E82402FCF371EB2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_466CC1DA23A804CC1440402FCF37AE63" xlink:to="loc_srt_MinimumMember_79CCC16D314AE1356E82402FCF371EB2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="loc_us-gaap_VariableRateAxis_371131C0D3316BBE7808402FCF3707A4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:to="loc_us-gaap_VariableRateAxis_371131C0D3316BBE7808402FCF3707A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_59F860A0847EE0C180B2402FCF377A5B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_371131C0D3316BBE7808402FCF3707A4" xlink:to="loc_us-gaap_VariableRateDomain_59F860A0847EE0C180B2402FCF377A5B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_6FFF530E63EFB1911A2D402FCF383C26" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_59F860A0847EE0C180B2402FCF377A5B" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_6FFF530E63EFB1911A2D402FCF383C26" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_DA62F8E568679E5935DE402FCF384F95" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_DA62F8E568679E5935DE402FCF384F95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_E0E9C3B45E30EE2A2B9F402FCF38D23C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_DA62F8E568679E5935DE402FCF384F95" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_E0E9C3B45E30EE2A2B9F402FCF38D23C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="loc_us-gaap_LineOfCreditMember_2EA488DF2508AD76A6D0402FCF385B10" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_E0E9C3B45E30EE2A2B9F402FCF38D23C" xlink:to="loc_us-gaap_LineOfCreditMember_2EA488DF2508AD76A6D0402FCF385B10" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_F3263EFFB0F4FE5884D1402FCF3937A1" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_F3263EFFB0F4FE5884D1402FCF3937A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_F5A1C8260F1529EE3B09402FCF39EB55" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_F3263EFFB0F4FE5884D1402FCF3937A1" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_F5A1C8260F1529EE3B09402FCF39EB55" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SiliconValleyBankMember" xlink:label="loc_vcyt_SiliconValleyBankMember_8BC474E3AFEF29260F73402FCF39E124" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_F5A1C8260F1529EE3B09402FCF39EB55" xlink:to="loc_vcyt_SiliconValleyBankMember_8BC474E3AFEF29260F73402FCF39E124" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_D4ACDB11B8183950CEEF402FCF39C652" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:to="loc_us-gaap_CreditFacilityAxis_D4ACDB11B8183950CEEF402FCF39C652" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_F08750E12544824E314B402FCF39EEA5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_D4ACDB11B8183950CEEF402FCF39C652" xlink:to="loc_us-gaap_CreditFacilityDomain_F08750E12544824E314B402FCF39EEA5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SecuredDebtMember" xlink:label="loc_us-gaap_SecuredDebtMember_9A1A89BA8AC2BA90B899402FCF3AECBD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_F08750E12544824E314B402FCF39EEA5" xlink:to="loc_us-gaap_SecuredDebtMember_9A1A89BA8AC2BA90B899402FCF3AECBD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_C65F9F67E2E31711AEA3402FCF3A47B7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_F08750E12544824E314B402FCF39EEA5" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_C65F9F67E2E31711AEA3402FCF3A47B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityLineItems" xlink:label="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_754F459BDB0F60B03241402FCF35D203" xlink:to="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_5EBC48A51A66FE4F3E9B402FCF3AEA8F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_5EBC48A51A66FE4F3E9B402FCF3AEA8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_C21B7A2C34FCBE5E9C77402FCF3BA132" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_C21B7A2C34FCBE5E9C77402FCF3BA132" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_28C080BEDC141FD55F87402FCF3B6D1B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_28C080BEDC141FD55F87402FCF3B6D1B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_0EF08314DA0E06C5A376402FCF3BB15B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_0EF08314DA0E06C5A376402FCF3BB15B" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtInstrumentPrepaymentPremium" xlink:label="loc_vcyt_DebtInstrumentPrepaymentPremium_A6720F7B853A36B64A6B402FCF3BF9B3" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_vcyt_DebtInstrumentPrepaymentPremium_A6720F7B853A36B64A6B402FCF3BF9B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_FBBD75F342521E968F1F402FCF3BB0A3" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_FBBD75F342521E968F1F402FCF3BB0A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentPeriodicPaymentTermsBalloonPaymentToBePaid" xlink:label="loc_us-gaap_DebtInstrumentPeriodicPaymentTermsBalloonPaymentToBePaid_ABEED3A6227277DB27B3402FCF3B224A" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_us-gaap_DebtInstrumentPeriodicPaymentTermsBalloonPaymentToBePaid_ABEED3A6227277DB27B3402FCF3B224A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_LiquidityRequirementMinimum" xlink:label="loc_vcyt_LiquidityRequirementMinimum_DEFD2E6C6EDA608995A1402FCF3BE647" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_vcyt_LiquidityRequirementMinimum_DEFD2E6C6EDA608995A1402FCF3BE647" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_C01B9F19BF89A1B75EEC402FCF3C51C5" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_30C1250477A8F30EF456402FCF3A3F43" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_C01B9F19BF89A1B75EEC402FCF3C51C5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtScheduleOfLoanAndSecurityAgreementDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_FB0EEFED62AE6EEBAF0949ADE0C3E669" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_FA22F07AFB704648F67F49ADE0C327F9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_FB0EEFED62AE6EEBAF0949ADE0C3E669" xlink:to="loc_us-gaap_DebtInstrumentTable_FA22F07AFB704648F67F49ADE0C327F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_FE34664E1E88CC25B77E49ADE0C3D9D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_FA22F07AFB704648F67F49ADE0C327F9" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_FE34664E1E88CC25B77E49ADE0C3D9D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_1F7042C48EE738C02C4949ADE0C3C40D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_FE34664E1E88CC25B77E49ADE0C3D9D3" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_1F7042C48EE738C02C4949ADE0C3C40D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="loc_us-gaap_LineOfCreditMember_154D6595E90ED56D400649ADE0C4B6C7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_1F7042C48EE738C02C4949ADE0C3C40D" xlink:to="loc_us-gaap_LineOfCreditMember_154D6595E90ED56D400649ADE0C4B6C7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_E4E74DACC76141A0229149ADE0C4E244" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_FA22F07AFB704648F67F49ADE0C327F9" xlink:to="loc_us-gaap_DebtInstrumentLineItems_E4E74DACC76141A0229149ADE0C4E244" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_1B42BA97AD1FDD6FAF8349ADE0C47176" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_E4E74DACC76141A0229149ADE0C4E244" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_1B42BA97AD1FDD6FAF8349ADE0C47176" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DebtInstrumentEndOfTermPaymentInterestAmount" xlink:label="loc_vcyt_DebtInstrumentEndOfTermPaymentInterestAmount_60E0137ADFA577C6949049ADE0C42634" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_E4E74DACC76141A0229149ADE0C4E244" xlink:to="loc_vcyt_DebtInstrumentEndOfTermPaymentInterestAmount_60E0137ADFA577C6949049ADE0C42634" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscount" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_24631712603F906E889D49ADE0C54990" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_E4E74DACC76141A0229149ADE0C4E244" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_24631712603F906E889D49ADE0C54990" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebt" xlink:label="loc_us-gaap_LongTermDebt_230B41D37971851DDE3D49ADE0C53158" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_E4E74DACC76141A0229149ADE0C4E244" xlink:to="loc_us-gaap_LongTermDebt_230B41D37971851DDE3D49ADE0C53158" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_F5759A15DCF4B14C0FCF5DDA891F7553" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfDebtTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfDebtTableTextBlock_8ADD214CA0683730F3815DDA892041CF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_F5759A15DCF4B14C0FCF5DDA891F7553" xlink:to="loc_us-gaap_ScheduleOfDebtTableTextBlock_8ADD214CA0683730F3815DDA892041CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock" xlink:label="loc_us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock_317923237CEF5CF717145DDA8920775B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_F5759A15DCF4B14C0FCF5DDA891F7553" xlink:to="loc_us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock_317923237CEF5CF717145DDA8920775B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_A682A63540FA6BA8A207E8A9990239CB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_8A881E2626BD22285FB1E8A999025398" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_A682A63540FA6BA8A207E8A9990239CB" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_8A881E2626BD22285FB1E8A999025398" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/FairValueMeasurementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_A2DCD1049EDB8865FAEF5FFB7CA8C615" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_A2DCD1049EDB8865FAEF5FFB7CA8C615" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_AC5952BA90D29F0818145FFEC6FFD5ED" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_AC5952BA90D29F0818145FFEC6FFD5ED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F39AC7414EC25FE9A7015FFEC8295AB4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_AC5952BA90D29F0818145FFEC6FFD5ED" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F39AC7414EC25FE9A7015FFEC8295AB4" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NanoStringMember" xlink:label="loc_vcyt_NanoStringMember_90E97D2D5C94EA447BBB5FFEC70DA057" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F39AC7414EC25FE9A7015FFEC8295AB4" xlink:to="loc_vcyt_NanoStringMember_90E97D2D5C94EA447BBB5FFEC70DA057" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1209C19C7601754849A15FFB7CAB9CF7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1209C19C7601754849A15FFB7CAB9CF7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2052E217A5FDD3C2F4025FFB7CAC891D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1209C19C7601754849A15FFB7CAB9CF7" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2052E217A5FDD3C2F4025FFB7CAC891D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_25366D5E1D351BEAFE815FFB7CAC731A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2052E217A5FDD3C2F4025FFB7CAC891D" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_25366D5E1D351BEAFE815FFB7CAC731A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsAxis" xlink:label="loc_us-gaap_CashAndCashEquivalentsAxis_C598EA5A9F6B21E6A3A15FFB7CACED3C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:to="loc_us-gaap_CashAndCashEquivalentsAxis_C598EA5A9F6B21E6A3A15FFB7CACED3C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_D02A528D66AD49DF05F75FFB7CAD9C56" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAxis_C598EA5A9F6B21E6A3A15FFB7CACED3C" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_D02A528D66AD49DF05F75FFB7CAD9C56" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_OvernightRepurchaseAgreementsMember" xlink:label="loc_vcyt_OvernightRepurchaseAgreementsMember_A69A5F076BEDBF7106B85FFB7CAD866A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_D02A528D66AD49DF05F75FFB7CAD9C56" xlink:to="loc_vcyt_OvernightRepurchaseAgreementsMember_A69A5F076BEDBF7106B85FFB7CAD866A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinancialInstrumentAxis" xlink:label="loc_us-gaap_FinancialInstrumentAxis_B5E2BD0435C0FBB9DE6F5FFB7CADA1FC" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:to="loc_us-gaap_FinancialInstrumentAxis_B5E2BD0435C0FBB9DE6F5FFB7CADA1FC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_DAEA2291AFE8C04343545FFB7CADBAA4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_B5E2BD0435C0FBB9DE6F5FFB7CADA1FC" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_DAEA2291AFE8C04343545FFB7CADBAA4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MoneyMarketFundsMember" xlink:label="loc_us-gaap_MoneyMarketFundsMember_7E9A85BC17354A4956CD5FFB7CAEF502" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_DAEA2291AFE8C04343545FFB7CADBAA4" xlink:to="loc_us-gaap_MoneyMarketFundsMember_7E9A85BC17354A4956CD5FFB7CAEF502" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseArrangementTypeAxis" xlink:label="loc_us-gaap_LeaseArrangementTypeAxis_E3837B22AC44C414632A5FFB7CAED360" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:to="loc_us-gaap_LeaseArrangementTypeAxis_E3837B22AC44C414632A5FFB7CAED360" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LeaseArrangementTypeDomain" xlink:label="loc_us-gaap_LeaseArrangementTypeDomain_B307CAB3FB3D40A3B6EC5FFB7CAE7AB7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeAxis_E3837B22AC44C414632A5FFB7CAED360" xlink:to="loc_us-gaap_LeaseArrangementTypeDomain_B307CAB3FB3D40A3B6EC5FFB7CAE7AB7" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember" xlink:label="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_FA7ECFA455E2C3C46FAE5FFB7CAE3D56" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeDomain_B307CAB3FB3D40A3B6EC5FFB7CAE7AB7" xlink:to="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_FA7ECFA455E2C3C46FAE5FFB7CAE3D56" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_40E04C85DC94D3E03E785FFB7CAFB7E7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_01F4CC7654BA7660981A5FFB7CAA697C" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_40E04C85DC94D3E03E785FFB7CAFB7E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_311D67BFC110DCB8E5D35FFB7CAFC9CE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_40E04C85DC94D3E03E785FFB7CAFB7E7" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_311D67BFC110DCB8E5D35FFB7CAFC9CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SecurityDeposit" xlink:label="loc_us-gaap_SecurityDeposit_EA52BB12DB57DB207F145FFB7CAF9895" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_40E04C85DC94D3E03E785FFB7CAFB7E7" xlink:to="loc_us-gaap_SecurityDeposit_EA52BB12DB57DB207F145FFB7CAF9895" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_F728C69EB5684353AD955FFEC6E6423F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_40E04C85DC94D3E03E785FFB7CAFB7E7" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_F728C69EB5684353AD955FFEC6E6423F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_BusinessCombinationContingentConsiderationCashtobePaid" xlink:label="loc_vcyt_BusinessCombinationContingentConsiderationCashtobePaid_52B5F655858D8011C7175FFEC6F3D75B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_40E04C85DC94D3E03E785FFB7CAFB7E7" xlink:to="loc_vcyt_BusinessCombinationContingentConsiderationCashtobePaid_52B5F655858D8011C7175FFEC6F3D75B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_0B2B9E68FCF876201A1AE8A996CB1073" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_9B515DBB14CBBB0380E4E8A996CB4FAB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_0B2B9E68FCF876201A1AE8A996CB1073" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_9B515DBB14CBBB0380E4E8A996CB4FAB" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_B26FA9EC4E5945446D9564B4468BE9BD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_E021A05732F5EEE7C4E664B4468B79D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B26FA9EC4E5945446D9564B4468BE9BD" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_E021A05732F5EEE7C4E664B4468B79D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_FCE7AC3E0D7C5E7B359364B4468BE218" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B26FA9EC4E5945446D9564B4468BE9BD" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_FCE7AC3E0D7C5E7B359364B4468BE218" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount" xlink:label="loc_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_D9BFB76C182145F7A5F964B4468BD845" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B26FA9EC4E5945446D9564B4468BE9BD" xlink:to="loc_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_D9BFB76C182145F7A5F964B4468BD845" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitAmount" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitAmount_E585A823182405EFC32764B4468B0549" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B26FA9EC4E5945446D9564B4468BE9BD" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitAmount_E585A823182405EFC32764B4468B0549" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLossCarryforwardsTable" xlink:label="loc_us-gaap_OperatingLossCarryforwardsTable_B738C56EB15009102BB864B4468B67A9" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_B26FA9EC4E5945446D9564B4468BE9BD" xlink:to="loc_us-gaap_OperatingLossCarryforwardsTable_B738C56EB15009102BB864B4468B67A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_B6472027CEC430396B7C64B4468C0018" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_B738C56EB15009102BB864B4468B67A9" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_B6472027CEC430396B7C64B4468C0018" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_C6E4BC1B83F9D263028564B4468CD40D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_B6472027CEC430396B7C64B4468C0018" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_C6E4BC1B83F9D263028564B4468CD40D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DomesticCountryMember" xlink:label="loc_us-gaap_DomesticCountryMember_15FB30256FACB62645E564B4468C0C25" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_C6E4BC1B83F9D263028564B4468CD40D" xlink:to="loc_us-gaap_DomesticCountryMember_15FB30256FACB62645E564B4468C0C25" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StateAndLocalJurisdictionMember" xlink:label="loc_us-gaap_StateAndLocalJurisdictionMember_FED556EC8D883811494664B4468D60BE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_C6E4BC1B83F9D263028564B4468CD40D" xlink:to="loc_us-gaap_StateAndLocalJurisdictionMember_FED556EC8D883811494664B4468D60BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_StatementGeographicalAxis" xlink:label="loc_srt_StatementGeographicalAxis_CC97F2DE844A080F8A5564B4468DB834" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_B738C56EB15009102BB864B4468B67A9" xlink:to="loc_srt_StatementGeographicalAxis_CC97F2DE844A080F8A5564B4468DB834" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="loc_srt_SegmentGeographicalDomain_9396592AEE395D613E5864B4468DC6EF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_CC97F2DE844A080F8A5564B4468DB834" xlink:to="loc_srt_SegmentGeographicalDomain_9396592AEE395D613E5864B4468DC6EF" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/stpr/2018/stpr-2018-01-31.xsd#stpr_CA" xlink:label="loc_stpr_CA_AD4B20F17F3E3421885B64B4468D1652" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_9396592AEE395D613E5864B4468DC6EF" xlink:to="loc_stpr_CA_AD4B20F17F3E3421885B64B4468D1652" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_OtherStatesNotSeparatelyDisclosedMember" xlink:label="loc_vcyt_OtherStatesNotSeparatelyDisclosedMember_B8268127391E22D3ECA964B4468D9222" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_9396592AEE395D613E5864B4468DC6EF" xlink:to="loc_vcyt_OtherStatesNotSeparatelyDisclosedMember_B8268127391E22D3ECA964B4468D9222" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLossCarryforwardsLineItems" xlink:label="loc_us-gaap_OperatingLossCarryforwardsLineItems_C88E9EA5004B1FDC1BBE64B4468E7CB2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_B738C56EB15009102BB864B4468B67A9" xlink:to="loc_us-gaap_OperatingLossCarryforwardsLineItems_C88E9EA5004B1FDC1BBE64B4468E7CB2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLossCarryforwards" xlink:label="loc_us-gaap_OperatingLossCarryforwards_5779E5B050828C41D1A964B4468E84BF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_C88E9EA5004B1FDC1BBE64B4468E7CB2" xlink:to="loc_us-gaap_OperatingLossCarryforwards_5779E5B050828C41D1A964B4468E84BF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TaxCreditCarryforwardAmount" xlink:label="loc_us-gaap_TaxCreditCarryforwardAmount_157C2E9405072B0D642564B4468ED75C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_C88E9EA5004B1FDC1BBE64B4468E7CB2" xlink:to="loc_us-gaap_TaxCreditCarryforwardAmount_157C2E9405072B0D642564B4468ED75C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefits" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_74388CD34D26885497F56514634BFBE9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_C88E9EA5004B1FDC1BBE64B4468E7CB2" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_74388CD34D26885497F56514634BFBE9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_2276AF549A5BA21B2354598E4F4EC071" xlink:type="locator" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract" xlink:label="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2276AF549A5BA21B2354598E4F4EC071" xlink:to="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_1D61487C1D1175D98BE8598E4F506235" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_1D61487C1D1175D98BE8598E4F506235" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DeferredTaxAssetsTaxCreditCarryforwardsResearchAndDevelopment" xlink:label="loc_vcyt_DeferredTaxAssetsTaxCreditCarryforwardsResearchAndDevelopment_ACC3ED10639DBF465065598E4F506CA2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_vcyt_DeferredTaxAssetsTaxCreditCarryforwardsResearchAndDevelopment_ACC3ED10639DBF465065598E4F506CA2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_528ABAFC68671D0F5A25598E4F50604E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_528ABAFC68671D0F5A25598E4F50604E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets" xlink:label="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_4D369709EFA59986CCCF598E4F504F9B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_4D369709EFA59986CCCF598E4F504F9B" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DeferredTaxAssetsOperatingLeaseLiability" xlink:label="loc_vcyt_DeferredTaxAssetsOperatingLeaseLiability_43D68388B571ABD38B11598E4F504C41" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_vcyt_DeferredTaxAssetsOperatingLeaseLiability_43D68388B571ABD38B11598E4F504C41" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DeferredTaxAssetsAccrualsDeferredRentAndOther" xlink:label="loc_vcyt_DeferredTaxAssetsAccrualsDeferredRentAndOther_FDF8F2E30678FD8B2AE1598E4F502DE5" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_vcyt_DeferredTaxAssetsAccrualsDeferredRentAndOther_FDF8F2E30678FD8B2AE1598E4F502DE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxAssetsGrossNoncurrent" xlink:label="loc_us-gaap_DeferredTaxAssetsGrossNoncurrent_83D6F8DB0DB64BC8F18C598E4F50DE54" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_us-gaap_DeferredTaxAssetsGrossNoncurrent_83D6F8DB0DB64BC8F18C598E4F50DE54" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TaxCreditCarryforwardValuationAllowance" xlink:label="loc_us-gaap_TaxCreditCarryforwardValuationAllowance_E8EBB1306EE4A1607463598E4F510578" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_us-gaap_TaxCreditCarryforwardValuationAllowance_E8EBB1306EE4A1607463598E4F510578" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxAssetsDeferredIncome" xlink:label="loc_us-gaap_DeferredTaxAssetsDeferredIncome_C495F847C8384C1FB52F598E4F51C3DB" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxAssetsNonCurrentAbstract_B30EF8A3BE7B006AB304598E4F4F1334" xlink:to="loc_us-gaap_DeferredTaxAssetsDeferredIncome_C495F847C8384C1FB52F598E4F51C3DB" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract" xlink:label="loc_vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract_88FADD3DA44371688ECD598E4F51B3DF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2276AF549A5BA21B2354598E4F4EC071" xlink:to="loc_vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract_88FADD3DA44371688ECD598E4F51B3DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_F1BCF43764E5109702A0598E4F511267" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract_88FADD3DA44371688ECD598E4F51B3DF" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_F1BCF43764E5109702A0598E4F511267" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts_44EA67156166A718862A598E4F52A6F0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract_88FADD3DA44371688ECD598E4F51B3DF" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts_44EA67156166A718862A598E4F52A6F0" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DeferredTaxLiabilitiesRightofUseAssets" xlink:label="loc_vcyt_DeferredTaxLiabilitiesRightofUseAssets_711C7734664815E346C0598E4F5268DF" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract_88FADD3DA44371688ECD598E4F51B3DF" xlink:to="loc_vcyt_DeferredTaxLiabilitiesRightofUseAssets_711C7734664815E346C0598E4F5268DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilities" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_356DB187872D8E4D6DF4598E4F520FB6" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract_88FADD3DA44371688ECD598E4F51B3DF" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_356DB187872D8E4D6DF4598E4F520FB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxLiabilities" xlink:label="loc_us-gaap_DeferredTaxLiabilities_48166C8492512A142D89598E4F527729" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ComponentsOfDeferredTaxLiabilitiesNonCurrentAbstract_88FADD3DA44371688ECD598E4F51B3DF" xlink:to="loc_us-gaap_DeferredTaxLiabilities_48166C8492512A142D89598E4F527729" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_B1D5A429EF536416EB3D598E4F52A2ED" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2276AF549A5BA21B2354598E4F4EC071" xlink:to="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_B1D5A429EF536416EB3D598E4F52A2ED" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxesIncomeTaxExaminationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_2F23BF3E0BBB23BF5249E8A996942615" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxExaminationTable" xlink:label="loc_us-gaap_IncomeTaxExaminationTable_9B75F06DE164D5E41E3BE8A9969541AA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_2F23BF3E0BBB23BF5249E8A996942615" xlink:to="loc_us-gaap_IncomeTaxExaminationTable_9B75F06DE164D5E41E3BE8A9969541AA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_098E86B5697E9E9DC38CE8A996957EAF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExaminationTable_9B75F06DE164D5E41E3BE8A9969541AA" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_098E86B5697E9E9DC38CE8A996957EAF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_771F0BCF8AE2A58BEFF5E8A99696CE39" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_098E86B5697E9E9DC38CE8A996957EAF" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_771F0BCF8AE2A58BEFF5E8A99696CE39" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DomesticCountryMember" xlink:label="loc_us-gaap_DomesticCountryMember_CB0782E7968A3D2B2572E8A99696851A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_771F0BCF8AE2A58BEFF5E8A99696CE39" xlink:to="loc_us-gaap_DomesticCountryMember_CB0782E7968A3D2B2572E8A99696851A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StateAndLocalJurisdictionMember" xlink:label="loc_us-gaap_StateAndLocalJurisdictionMember_B15BA76EB00B18A29ABDE8A996964044" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_771F0BCF8AE2A58BEFF5E8A99696CE39" xlink:to="loc_us-gaap_StateAndLocalJurisdictionMember_B15BA76EB00B18A29ABDE8A996964044" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxExaminationLineItems" xlink:label="loc_us-gaap_IncomeTaxExaminationLineItems_8781F125FD31DF6448C0E8A9969634A0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExaminationTable_9B75F06DE164D5E41E3BE8A9969541AA" xlink:to="loc_us-gaap_IncomeTaxExaminationLineItems_8781F125FD31DF6448C0E8A9969634A0" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_IncomeTaxExaminationPeriod" xlink:label="loc_vcyt_IncomeTaxExaminationPeriod_A74945FEEC781C4CF243E8A996963E60" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExaminationLineItems_8781F125FD31DF6448C0E8A9969634A0" xlink:to="loc_vcyt_IncomeTaxExaminationPeriod_A74945FEEC781C4CF243E8A996963E60" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_455FC05DA0C12F54DF2BE8A996C897CF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_13054FB1A68CD051C894E8A996C893F3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_455FC05DA0C12F54DF2BE8A996C897CF" xlink:to="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_13054FB1A68CD051C894E8A996C893F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_89C693DE5B183485AFE1E8A996C86F99" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_455FC05DA0C12F54DF2BE8A996C897CF" xlink:to="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_89C693DE5B183485AFE1E8A996C86F99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock_F556441BC27FE13C5AA9E8A996C8E967" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_455FC05DA0C12F54DF2BE8A996C897CF" xlink:to="loc_us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock_F556441BC27FE13C5AA9E8A996C8E967" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxesTaxProvisionDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_8D280941D7C6EFBDFE76402FCE6D47BA" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8D280941D7C6EFBDFE76402FCE6D47BA" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:label="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_3B6D1059D6E88B79E73C402FCE6E02FD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_3B6D1059D6E88B79E73C402FCE6E02FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes" xlink:label="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_E873E395867087472758402FCE6E2BF7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_E873E395867087472758402FCE6E2BF7" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficerCompensationAmount" xlink:label="loc_vcyt_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficerCompensationAmount_84953176AF1D3EBF80CA402FCE6E090F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_vcyt_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficerCompensationAmount_84953176AF1D3EBF80CA402FCE6E090F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitAmount" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitAmount_970A8A6B52E072C98B8240422EB043FA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitAmount_970A8A6B52E072C98B8240422EB043FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpense" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpense_CB1D8306674998FFB0A3402FCE6ED5E0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpense_CB1D8306674998FFB0A3402FCE6ED5E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost_B5CC1BCFA888AE5A7AFD402FCE6F9110" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost_B5CC1BCFA888AE5A7AFD402FCE6F9110" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxReconciliationTaxCredits" xlink:label="loc_us-gaap_IncomeTaxReconciliationTaxCredits_5D843A9E1909A4A63028402FCE6FDF1A" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxReconciliationTaxCredits_5D843A9E1909A4A63028402FCE6FDF1A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_72661BAAC346D333B061402FCE6F63F8" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_72661BAAC346D333B061402FCE6F63F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_73E06BFCE7E07CDFD964402FCE6FB696" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_73E06BFCE7E07CDFD964402FCE6FB696" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_BE8AA83EAC412161D68D402FCE6FA308" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsIncomeTaxReconciliationAbstract_3278B054581B15C1FFBC402FCE6DE487" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_BE8AA83EAC412161D68D402FCE6FA308" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxesUncertainTaxPositionsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_E399601759359DC661B8E8A9969CFF93" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward" xlink:label="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_E399601759359DC661B8E8A9969CFF93" xlink:to="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefits" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_432E72D316087CE5DDC9E8A9969C988F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_432E72D316087CE5DDC9E8A9969C988F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_8921657D49E48E83361CE8A9969D01A6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_8921657D49E48E83361CE8A9969D01A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions_E6FC4D57AEE780F966D6E8A9969DFCCC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions_E6FC4D57AEE780F966D6E8A9969DFCCC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_7B472FAE841EEE30B5D8E8A9969EBD3C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_7B472FAE841EEE30B5D8E8A9969EBD3C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations_D5A585EFE09212716729E8A9969E18E9" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations_D5A585EFE09212716729E8A9969E18E9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefits" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_FB168605D4B487C09434E8A9969EED17" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_240104B49435F7DA2DD8E8A9969CB325" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_FB168605D4B487C09434E8A9969EED17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_05A47EF27583A94D56E4E8A9969E5C5C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_E399601759359DC661B8E8A9969CFF93" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_05A47EF27583A94D56E4E8A9969E5C5C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/NetLossPerShare" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_EC2A5D42A40BCA3DF53EE8A99971DE9A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_E65631AB94629A2CCE45E8A99971AEB2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_EC2A5D42A40BCA3DF53EE8A99971DE9A" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_E65631AB94629A2CCE45E8A99971AEB2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/NetLossPerShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_CED2B99AB1F815D6FEF1F75CA47F12D9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_DD949C49C4774371B772F75CA47FFFFA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_CED2B99AB1F815D6FEF1F75CA47F12D9" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_DD949C49C4774371B772F75CA47FFFFA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_8C304CB2E609996423EAF75CA4801795" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_DD949C49C4774371B772F75CA47FFFFA" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_8C304CB2E609996423EAF75CA4801795" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C90B76C0DD58B4A4E64FF75CA4801E3A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_8C304CB2E609996423EAF75CA4801795" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C90B76C0DD58B4A4E64FF75CA4801E3A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EmployeeAndNonEmployeeStockOptionMember" xlink:label="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_86768A36CCD26F17A9D8F75CA480E76B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C90B76C0DD58B4A4E64FF75CA4801E3A" xlink:to="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_86768A36CCD26F17A9D8F75CA480E76B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockMember" xlink:label="loc_us-gaap_EmployeeStockMember_3CFE04EACED55A0279D7F75CA48019DA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C90B76C0DD58B4A4E64FF75CA4801E3A" xlink:to="loc_us-gaap_EmployeeStockMember_3CFE04EACED55A0279D7F75CA48019DA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_176F88232037FC93EE29F75CA48167F0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C90B76C0DD58B4A4E64FF75CA4801E3A" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_176F88232037FC93EE29F75CA48167F0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_45AAC7AF0D61FB51DD81F75CA481F817" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_DD949C49C4774371B772F75CA47FFFFA" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_45AAC7AF0D61FB51DD81F75CA481F817" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_625B4D1B5B9102D5A618F75CA4819C37" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_45AAC7AF0D61FB51DD81F75CA481F817" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_625B4D1B5B9102D5A618F75CA4819C37" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/NetLossPerShareTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_49BE95544FEB392EE630E8A9996DF387" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_D17F13C3DA8841D56F48E8A9996D984D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_49BE95544FEB392EE630E8A9996DF387" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_D17F13C3DA8841D56F48E8A9996D984D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusiness" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_4E8A587C2694FBA7ACAEE8A999E0CE1C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock" xlink:label="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_BEA7DE64248B37874E21E8A999E08A46" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_4E8A587C2694FBA7ACAEE8A999E0CE1C" xlink:to="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_BEA7DE64248B37874E21E8A999E08A46" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_A4ADF1CFC4CFE15374EA402FCFEECA9E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NumberOfOperatingSegments" xlink:label="loc_us-gaap_NumberOfOperatingSegments_55701C13C4E4A099D134402FCFEE379F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_A4ADF1CFC4CFE15374EA402FCFEECA9E" xlink:to="loc_us-gaap_NumberOfOperatingSegments_55701C13C4E4A099D134402FCFEE379F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SelectedQuarterlyFinancialDataUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_QuarterlyFinancialInformationDisclosureAbstract" xlink:label="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_7AC89A7E66A253777770E8A996764C80" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_QuarterlyFinancialInformationTextBlock" xlink:label="loc_us-gaap_QuarterlyFinancialInformationTextBlock_C898E25800DD856C981BE8A996774570" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_7AC89A7E66A253777770E8A996764C80" xlink:to="loc_us-gaap_QuarterlyFinancialInformationTextBlock_C898E25800DD856C981BE8A996774570" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SelectedQuarterlyFinancialDataUnauditedDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_QuarterlyFinancialInformationDisclosureAbstract" xlink:label="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_49D84B1D1A5342E18C9AE8A9966E0D45" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SelectedQuarterlyFinancialInformationAbstract" xlink:label="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B9F91EF8692CF634EC18E8A9966EE6D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_49D84B1D1A5342E18C9AE8A9966E0D45" xlink:to="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B9F91EF8692CF634EC18E8A9966EE6D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_12AC4107A362E57D7605E8A9966EFCFE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B9F91EF8692CF634EC18E8A9966EE6D6" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_12AC4107A362E57D7605E8A9966EFCFE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_408E3A5CAC2B7196BBF9E8A9966EE929" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B9F91EF8692CF634EC18E8A9966EE6D6" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_408E3A5CAC2B7196BBF9E8A9966EE929" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_BF801196A0753DF46D16E8A9966FB853" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B9F91EF8692CF634EC18E8A9966EE6D6" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_BF801196A0753DF46D16E8A9966FB853" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_3272DF2E10DCFFFA513DE8A9966FAE31" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SelectedQuarterlyFinancialInformationAbstract_B9F91EF8692CF634EC18E8A9966EE6D6" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_3272DF2E10DCFFFA513DE8A9966FAE31" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SelectedQuarterlyFinancialDataUnauditedTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_QuarterlyFinancialInformationDisclosureAbstract" xlink:label="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_FDC6218A26F0D027908CE8A996726F65" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock_C1299FCCFAD5730C83B2E8A996734B0A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_FDC6218A26F0D027908CE8A996726F65" xlink:to="loc_us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock_C1299FCCFAD5730C83B2E8A996734B0A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockIncentivePlans" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1ED46E5FC143B2B2819AE8A997B0DF35" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_BC502E07EDA456252D15E8A997B01B4D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1ED46E5FC143B2B2819AE8A997B0DF35" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_BC502E07EDA456252D15E8A997B01B4D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockIncentivePlansActivityUnderStockOptionPlansDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_C831B92C7A062413D49B49ADE056F83B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_7F9DEB29E0F36E1725D749ADE05690DC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_C831B92C7A062413D49B49ADE056F83B" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_7F9DEB29E0F36E1725D749ADE05690DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_89B3CB79EC7242786A4F49ADE056C0B1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_7F9DEB29E0F36E1725D749ADE05690DC" xlink:to="loc_us-gaap_AwardTypeAxis_89B3CB79EC7242786A4F49ADE056C0B1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_913374C4E482AEFCD56849ADE056AACC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_89B3CB79EC7242786A4F49ADE056C0B1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_913374C4E482AEFCD56849ADE056AACC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockOptionMember" xlink:label="loc_us-gaap_EmployeeStockOptionMember_4460A9C6974D004CB10449ADE0564FA2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_913374C4E482AEFCD56849ADE056AACC" xlink:to="loc_us-gaap_EmployeeStockOptionMember_4460A9C6974D004CB10449ADE0564FA2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_5DE73EF626E6AEBE01AB49ADE057836D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_913374C4E482AEFCD56849ADE056AACC" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_5DE73EF626E6AEBE01AB49ADE057836D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EmployeeAndNonEmployeeStockOptionMember" xlink:label="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_34624FE4A4657E83612649B3077DE646" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_913374C4E482AEFCD56849ADE056AACC" xlink:to="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_34624FE4A4657E83612649B3077DE646" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_7F9DEB29E0F36E1725D749ADE05690DC" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_07A3C13B93DF6E6BE55849ADE0578DDE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_07A3C13B93DF6E6BE55849ADE0578DDE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_666CAF4CB9A9BAB7D6F349ADE0586CF8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_666CAF4CB9A9BAB7D6F349ADE0586CF8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_17315BA1E6979EEBC9C949ADE0589AB1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_17315BA1E6979EEBC9C949ADE0589AB1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_E8F497BBD24B0D4B2D8C49ADE05851E4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_E8F497BBD24B0D4B2D8C49ADE05851E4" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsVestedNumberofSharesTaxPortion" xlink:label="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsVestedNumberofSharesTaxPortion_F12EA9BCE3A02D8AA93149ADE058F9CC" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:to="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsVestedNumberofSharesTaxPortion_F12EA9BCE3A02D8AA93149ADE058F9CC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_64ABEB5DA4FBCF7B273C49ADE05843FD" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrantRollForward_83CB9ED98335313D326849ADE05779D2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_64ABEB5DA4FBCF7B273C49ADE05843FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_94F1F0E0898A3D3F4AD949ADE059B81A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_94F1F0E0898A3D3F4AD949ADE059B81A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_8734BB0A57ED12568A7149ADE05954CC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_8734BB0A57ED12568A7149ADE05954CC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_6BDDD96524C2316B620549ADE059DA8F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_6BDDD96524C2316B620549ADE059DA8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_3FD96F3912D64572B45949ADE0590657" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_3FD96F3912D64572B45949ADE0590657" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_D9FFA5D4D6CEAEA2F9C049ADE059D995" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_D9FFA5D4D6CEAEA2F9C049ADE059D995" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_CF72B92DDAA82B87220949ADE05A4044" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_DEC6F1D1D2B1F75EEC4D49ADE0586B08" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_CF72B92DDAA82B87220949ADE05A4044" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_C5316E280CC888C574EB49ADE05AFF00" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_C5316E280CC888C574EB49ADE05AFF00" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_4CBBBDD61A0D2C1B2E1149ADE05A5FB4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_4CBBBDD61A0D2C1B2E1149ADE05A5FB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_AA80A08FCE5EC53FD78049ADE05AC69C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_AA80A08FCE5EC53FD78049ADE05AC69C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_7F4C9089BC25716E8D5049ADE05A1801" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_AA80A08FCE5EC53FD78049ADE05AC69C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_7F4C9089BC25716E8D5049ADE05A1801" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_1F2E94C4D4BF28E7206A49ADE05AD1EE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_AA80A08FCE5EC53FD78049ADE05AC69C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_1F2E94C4D4BF28E7206A49ADE05AD1EE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_9A615515123FDB002EF249ADE05BF615" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_AA80A08FCE5EC53FD78049ADE05AC69C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_9A615515123FDB002EF249ADE05BF615" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_A0C387E7B97D218E23F949ADE05BF805" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_AA80A08FCE5EC53FD78049ADE05AC69C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_A0C387E7B97D218E23F949ADE05BF805" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_188C5909056F2345920C49ADE05B6F0A" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_AA80A08FCE5EC53FD78049ADE05AC69C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_188C5909056F2345920C49ADE05B6F0A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_CC6BC12D5C380BC6866749ADE05BC2FB" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_CC6BC12D5C380BC6866749ADE05BC2FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_91260C2CF94CB129B0BE49ADE05B3EDC" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_91260C2CF94CB129B0BE49ADE05B3EDC" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeAbstract" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeAbstract_AC4C6EDE9CA7DEEAAE1F49ADE05B9E2E" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeAbstract_AC4C6EDE9CA7DEEAAE1F49ADE05B9E2E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_806C048C903AECF637EA49ADE05CB769" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeAbstract_AC4C6EDE9CA7DEEAAE1F49ADE05B9E2E" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_806C048C903AECF637EA49ADE05CB769" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_A181F168507779ED39C249ADE05C7965" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeAbstract_AC4C6EDE9CA7DEEAAE1F49ADE05B9E2E" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_A181F168507779ED39C249ADE05C7965" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_6B5B19C9E7E797D7C89049ADE05C5870" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeAbstract_AC4C6EDE9CA7DEEAAE1F49ADE05B9E2E" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_6B5B19C9E7E797D7C89049ADE05C5870" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueAbstract" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueAbstract_4067E110C6243725D62949ADE05CE49B" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D47C962CF7AFD694441E49ADE057E806" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueAbstract_4067E110C6243725D62949ADE05CE49B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_2B096C8E97753681995B49ADE05CA67B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueAbstract_4067E110C6243725D62949ADE05CE49B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_2B096C8E97753681995B49ADE05CA67B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_3A8CEF733196F38B89C849ADE05DC31F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueAbstract_4067E110C6243725D62949ADE05CE49B" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_3A8CEF733196F38B89C849ADE05DC31F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_37CBCE392D00902C8B5749ADE05DE300" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAggregateIntrinsicValueAbstract_4067E110C6243725D62949ADE05CE49B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_37CBCE392D00902C8B5749ADE05DE300" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockIncentivePlansAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1FE1F46EA2DAF54FF33E782B0BE18086" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_65E5E82C039D3E75BDF1782B0BE3648D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1FE1F46EA2DAF54FF33E782B0BE18086" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_65E5E82C039D3E75BDF1782B0BE3648D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_90C31934EAE727247832782B0BE31FCE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_65E5E82C039D3E75BDF1782B0BE3648D" xlink:to="loc_us-gaap_AwardTypeAxis_90C31934EAE727247832782B0BE31FCE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4989175A7D67C6906748782B0BE3715F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_90C31934EAE727247832782B0BE31FCE" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4989175A7D67C6906748782B0BE3715F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NonEmployeeStockOptionMember" xlink:label="loc_vcyt_NonEmployeeStockOptionMember_C4A32C5DB09B0EE23B19782D30D4108E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4989175A7D67C6906748782B0BE3715F" xlink:to="loc_vcyt_NonEmployeeStockOptionMember_C4A32C5DB09B0EE23B19782D30D4108E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockOptionMember" xlink:label="loc_us-gaap_EmployeeStockOptionMember_CE41CCFBD91604BF4F50782B0BE4CB17" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4989175A7D67C6906748782B0BE3715F" xlink:to="loc_us-gaap_EmployeeStockOptionMember_CE41CCFBD91604BF4F50782B0BE4CB17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_B4776D110C18FDB02D52782B0BE44682" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4989175A7D67C6906748782B0BE3715F" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_B4776D110C18FDB02D52782B0BE44682" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_DD6888C8D3D3082B9158782B0BE443EE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_65E5E82C039D3E75BDF1782B0BE3648D" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_DD6888C8D3D3082B9158782B0BE443EE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_C38FE5BCD5837EADAC0E782B0BE41FB8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_DD6888C8D3D3082B9158782B0BE443EE" xlink:to="loc_us-gaap_EquityComponentDomain_C38FE5BCD5837EADAC0E782B0BE41FB8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_69F72DCD5FF78057CD69782B0BE495BE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_C38FE5BCD5837EADAC0E782B0BE41FB8" xlink:to="loc_us-gaap_CommonStockMember_69F72DCD5FF78057CD69782B0BE495BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_65E5E82C039D3E75BDF1782B0BE3648D" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharePrice" xlink:label="loc_us-gaap_SharePrice_1444B42019D9519ABF27782B0BE55BAC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:to="loc_us-gaap_SharePrice_1444B42019D9519ABF27782B0BE55BAC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_2190AC5FD3A2BA1473FB782B0BE5B9A9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_2190AC5FD3A2BA1473FB782B0BE5B9A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_42408A397661DA102DC9782B0BE572A2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_42408A397661DA102DC9782B0BE572A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_433F96F921EB9CB73971782B0BE5794F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_433F96F921EB9CB73971782B0BE5794F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_1B0F2FC8FE8492010AD6782B0BEB2774" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_1B0F2FC8FE8492010AD6782B0BEB2774" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_3F7195CE94D064361EAC782B0BEB553E" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_3F7195CE94D064361EAC782B0BEB553E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_6E92B39F9FD774E1D99B782CF71D1C48" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_C44C8CF97D009B394F33782B0BE5B734" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_6E92B39F9FD774E1D99B782CF71D1C48" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockIncentivePlansStockBasedCompensationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_482DB262824776C53D98363F70EBB449" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_CBEC0F0126D141454455363F70EB1A92" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_482DB262824776C53D98363F70EBB449" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_CBEC0F0126D141454455363F70EB1A92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_2FEB1CCCFC058E8A44F5363F70EBADE1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_CBEC0F0126D141454455363F70EB1A92" xlink:to="loc_us-gaap_PlanNameAxis_2FEB1CCCFC058E8A44F5363F70EBADE1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_ECBCEDE2358528ECCA21363F70EC6304" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_2FEB1CCCFC058E8A44F5363F70EBADE1" xlink:to="loc_us-gaap_PlanNameDomain_ECBCEDE2358528ECCA21363F70EC6304" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_StockPlan2008Member" xlink:label="loc_vcyt_StockPlan2008Member_FE6D92D710C84D3DAEE6363F70ECC2EF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_ECBCEDE2358528ECCA21363F70EC6304" xlink:to="loc_vcyt_StockPlan2008Member_FE6D92D710C84D3DAEE6363F70ECC2EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_B50D200FD5C0A9BEAB9F363F70ECE64F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_CBEC0F0126D141454455363F70EB1A92" xlink:to="loc_srt_RangeAxis_B50D200FD5C0A9BEAB9F363F70ECE64F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_9A12D6F246BB6CEC721F363F70EC449B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_B50D200FD5C0A9BEAB9F363F70ECE64F" xlink:to="loc_srt_RangeMember_9A12D6F246BB6CEC721F363F70EC449B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_109F28B8A7044A36E485363F70ED02E7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9A12D6F246BB6CEC721F363F70EC449B" xlink:to="loc_srt_MinimumMember_109F28B8A7044A36E485363F70ED02E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_D66F86F26F7851B14C97363F70EDA93B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9A12D6F246BB6CEC721F363F70EC449B" xlink:to="loc_srt_MaximumMember_D66F86F26F7851B14C97363F70EDA93B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_A6576DC220C801C32019363F70ED63FD" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_CBEC0F0126D141454455363F70EB1A92" xlink:to="loc_us-gaap_AwardTypeAxis_A6576DC220C801C32019363F70ED63FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_65BC7E3E9A7C952E8720363F70EDC92C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_A6576DC220C801C32019363F70ED63FD" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_65BC7E3E9A7C952E8720363F70EDC92C" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EmployeeAndNonEmployeeStockOptionExcludingBonusCompensationMember" xlink:label="loc_vcyt_EmployeeAndNonEmployeeStockOptionExcludingBonusCompensationMember_95519D4793D231163677363F70ED15AE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_65BC7E3E9A7C952E8720363F70EDC92C" xlink:to="loc_vcyt_EmployeeAndNonEmployeeStockOptionExcludingBonusCompensationMember_95519D4793D231163677363F70ED15AE" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EmployeeStockOptionExcludingBonusCompensationMember" xlink:label="loc_vcyt_EmployeeStockOptionExcludingBonusCompensationMember_80AC0BB221D01889FB5E363F70EE0C82" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_65BC7E3E9A7C952E8720363F70EDC92C" xlink:to="loc_vcyt_EmployeeStockOptionExcludingBonusCompensationMember_80AC0BB221D01889FB5E363F70EE0C82" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NonEmployeeStockOptionMember" xlink:label="loc_vcyt_NonEmployeeStockOptionMember_E9BA2FC39A99EE3D2E77363F70EE5202" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_65BC7E3E9A7C952E8720363F70EDC92C" xlink:to="loc_vcyt_NonEmployeeStockOptionMember_E9BA2FC39A99EE3D2E77363F70EE5202" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockMember" xlink:label="loc_us-gaap_EmployeeStockMember_19ABB678541B466303AA363F70EE2E57" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_65BC7E3E9A7C952E8720363F70EDC92C" xlink:to="loc_us-gaap_EmployeeStockMember_19ABB678541B466303AA363F70EE2E57" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_865305253165B33601AA363F70EEFCD4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_CBEC0F0126D141454455363F70EB1A92" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_865305253165B33601AA363F70EEFCD4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_5AD0EE85C3ECD82EBC01363F70EE335C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_865305253165B33601AA363F70EEFCD4" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_5AD0EE85C3ECD82EBC01363F70EE335C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostOfSalesMember" xlink:label="loc_us-gaap_CostOfSalesMember_4A8E23BBF1AF849E7CA6363F70EF245A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_5AD0EE85C3ECD82EBC01363F70EE335C" xlink:to="loc_us-gaap_CostOfSalesMember_4A8E23BBF1AF849E7CA6363F70EF245A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_6A1A97B18CE03A599449363F70EF2B6F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_5AD0EE85C3ECD82EBC01363F70EE335C" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_6A1A97B18CE03A599449363F70EF2B6F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SellingAndMarketingExpenseMember" xlink:label="loc_us-gaap_SellingAndMarketingExpenseMember_D8094780EDAB4F50FF93363F70EF3190" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_5AD0EE85C3ECD82EBC01363F70EE335C" xlink:to="loc_us-gaap_SellingAndMarketingExpenseMember_D8094780EDAB4F50FF93363F70EF3190" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GeneralAndAdministrativeExpenseMember" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_5C10CDA86802357FC52B363F70EFD20C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_5AD0EE85C3ECD82EBC01363F70EE335C" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_5C10CDA86802357FC52B363F70EFD20C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_81136EBAD4D573314C2E363F70EF9C15" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_CBEC0F0126D141454455363F70EB1A92" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_81136EBAD4D573314C2E363F70EF9C15" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_D64C278517B7A8C12591363F70F05750" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_81136EBAD4D573314C2E363F70EF9C15" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_D64C278517B7A8C12591363F70F05750" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_166029B88A26841F4835363F70F05E70" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_81136EBAD4D573314C2E363F70EF9C15" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_166029B88A26841F4835363F70F05E70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_DFAEBD3CF7F86B10AA04363F70F0D408" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_81136EBAD4D573314C2E363F70EF9C15" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_DFAEBD3CF7F86B10AA04363F70F0D408" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_A4F97AEC3E2C03EBD93A363F70F5F0BB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_81136EBAD4D573314C2E363F70EF9C15" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_A4F97AEC3E2C03EBD93A363F70F5F0BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_2311C1FC23627B6A5DC4363F70F656EF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_A4F97AEC3E2C03EBD93A363F70F5F0BB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_2311C1FC23627B6A5DC4363F70F656EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_A7F48EF650C153D281C6363F70F67613" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_A4F97AEC3E2C03EBD93A363F70F5F0BB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_A7F48EF650C153D281C6363F70F67613" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_4B357BD19DCCD3AFD312363F70F6A205" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_A4F97AEC3E2C03EBD93A363F70F5F0BB" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_4B357BD19DCCD3AFD312363F70F6A205" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_33F9033BF7DF6A26292A363F70F6355B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_A4F97AEC3E2C03EBD93A363F70F5F0BB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_33F9033BF7DF6A26292A363F70F6355B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_11C44B8DB49B24DC3458363F70F60B43" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsAndMethodologyAbstract_A4F97AEC3E2C03EBD93A363F70F5F0BB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_11C44B8DB49B24DC3458363F70F60B43" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockIncentivePlansStockIncentivePlansEsppDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_6F2A5FADEE7465CD7485E8A996FD8270" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_258FD03E40053B396BB8E8A996FE45BF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_6F2A5FADEE7465CD7485E8A996FD8270" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_258FD03E40053B396BB8E8A996FE45BF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_9AE266596006A0374A08E8A996FE4366" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_258FD03E40053B396BB8E8A996FE45BF" xlink:to="loc_us-gaap_AwardTypeAxis_9AE266596006A0374A08E8A996FE4366" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5DCD08B22157501A5599E8A996FFA0ED" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_9AE266596006A0374A08E8A996FE4366" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5DCD08B22157501A5599E8A996FFA0ED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockMember" xlink:label="loc_us-gaap_EmployeeStockMember_FFCD2014C1242AC3046BE8A997002DA4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5DCD08B22157501A5599E8A996FFA0ED" xlink:to="loc_us-gaap_EmployeeStockMember_FFCD2014C1242AC3046BE8A997002DA4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_9B3B2C8D504E45DC8754E8A99701A428" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_258FD03E40053B396BB8E8A996FE45BF" xlink:to="loc_srt_RangeAxis_9B3B2C8D504E45DC8754E8A99701A428" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_65EE61335C23C5627A9FE8A9970129CA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_9B3B2C8D504E45DC8754E8A99701A428" xlink:to="loc_srt_RangeMember_65EE61335C23C5627A9FE8A9970129CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_9B8017EE836AD399B6E0E8A99702AA0C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_65EE61335C23C5627A9FE8A9970129CA" xlink:to="loc_srt_MinimumMember_9B8017EE836AD399B6E0E8A99702AA0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_4D5C35830B512F07306FE8A99703FB3A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_258FD03E40053B396BB8E8A996FE45BF" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_4D5C35830B512F07306FE8A99703FB3A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOfferingPeriodMaximum" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOfferingPeriodMaximum_F86E7FF0B62808B3648BE8A99703C23D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_4D5C35830B512F07306FE8A99703FB3A" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOfferingPeriodMaximum_F86E7FF0B62808B3648BE8A99703C23D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_6BDA19C260ED62744508E8A99703D304" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_4D5C35830B512F07306FE8A99703FB3A" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_6BDA19C260ED62744508E8A99703D304" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPurchasePeriod" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPurchasePeriod_1D1B8BFB2F3E0A9669E7E8A99703F32A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_4D5C35830B512F07306FE8A99703FB3A" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPurchasePeriod_1D1B8BFB2F3E0A9669E7E8A99703F32A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumValueOfSharesPerEmployee" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumValueOfSharesPerEmployee_A9882DE47208819760ADE8A997031AC9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_4D5C35830B512F07306FE8A99703FB3A" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumValueOfSharesPerEmployee_A9882DE47208819760ADE8A997031AC9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockIncentivePlansStockOptionPlansDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_45FC87EDF5C56294563EE8A9977688B2" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_45FC87EDF5C56294563EE8A9977688B2" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VestingAxis" xlink:label="loc_us-gaap_VestingAxis_2E4C7A64700F6783F05CE8A997782D8E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:to="loc_us-gaap_VestingAxis_2E4C7A64700F6783F05CE8A997782D8E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VestingDomain" xlink:label="loc_us-gaap_VestingDomain_005A32D72FD677C97F47E8A99779C851" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingAxis_2E4C7A64700F6783F05CE8A997782D8E" xlink:to="loc_us-gaap_VestingDomain_005A32D72FD677C97F47E8A99779C851" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheOneMember" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_5B256E5F8A6707931002E8A997793DF2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_005A32D72FD677C97F47E8A99779C851" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_5B256E5F8A6707931002E8A997793DF2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheTwoMember" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheTwoMember_2D4B72DE5C31B20E7412E8A9977941EB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_005A32D72FD677C97F47E8A99779C851" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheTwoMember_2D4B72DE5C31B20E7412E8A9977941EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheThreeMember" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheThreeMember_AA077794B2292FA3239AE8A9977AD475" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_005A32D72FD677C97F47E8A99779C851" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheThreeMember_AA077794B2292FA3239AE8A9977AD475" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_23181CA161F0A0DEFF30E8A9977AD78D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:to="loc_us-gaap_PlanNameAxis_23181CA161F0A0DEFF30E8A9977AD78D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_B86BD3326AC00013728FE8A9977B53D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_23181CA161F0A0DEFF30E8A9977AD78D" xlink:to="loc_us-gaap_PlanNameDomain_B86BD3326AC00013728FE8A9977B53D7" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_StockPlan2008Member" xlink:label="loc_vcyt_StockPlan2008Member_5097F8D135936CDC5E39E8A9977C166B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_B86BD3326AC00013728FE8A9977B53D7" xlink:to="loc_vcyt_StockPlan2008Member_5097F8D135936CDC5E39E8A9977C166B" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_StockIncentivePlan2013Member" xlink:label="loc_vcyt_StockIncentivePlan2013Member_7777CE63DAC9296D117CE8A9977CE711" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_B86BD3326AC00013728FE8A9977B53D7" xlink:to="loc_vcyt_StockIncentivePlan2013Member_7777CE63DAC9296D117CE8A9977CE711" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_2689CD2BCD898778B289E8A9977C3C91" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:to="loc_us-gaap_AwardTypeAxis_2689CD2BCD898778B289E8A9977C3C91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_B49866D7011C39AFC63BE8A9977D7C12" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_2689CD2BCD898778B289E8A9977C3C91" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_B49866D7011C39AFC63BE8A9977D7C12" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_IncentiveStockOptionsMember" xlink:label="loc_vcyt_IncentiveStockOptionsMember_AE17838D5858E30B0CA0E8A9977DEFC4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_B49866D7011C39AFC63BE8A9977D7C12" xlink:to="loc_vcyt_IncentiveStockOptionsMember_AE17838D5858E30B0CA0E8A9977DEFC4" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NonStatutoryStockOptionsMember" xlink:label="loc_vcyt_NonStatutoryStockOptionsMember_59066D81E54A1E94541EE8A9977DB668" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_B49866D7011C39AFC63BE8A9977D7C12" xlink:to="loc_vcyt_NonStatutoryStockOptionsMember_59066D81E54A1E94541EE8A9977DB668" xlink:type="arc" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_B49866D7011C39AFC63BE8A9977D7C12" xlink:to="loc_vcyt_StockIncentivePlan2013Member_7777CE63DAC9296D117CE8A9977CE711" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockOptionMember" xlink:label="loc_us-gaap_EmployeeStockOptionMember_AD97E107FAACD60AC61CE8A9977E624F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_B49866D7011C39AFC63BE8A9977D7C12" xlink:to="loc_us-gaap_EmployeeStockOptionMember_AD97E107FAACD60AC61CE8A9977E624F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_TitleOfIndividualAxis" xlink:label="loc_srt_TitleOfIndividualAxis_D19CEC5B6044A26D2C01E8A9977E5889" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:to="loc_srt_TitleOfIndividualAxis_D19CEC5B6044A26D2C01E8A9977E5889" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_TitleOfIndividualWithRelationshipToEntityDomain" xlink:label="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_626C66AA791A0D02EBA2E8A9977ED46E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualAxis_D19CEC5B6044A26D2C01E8A9977E5889" xlink:to="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_626C66AA791A0D02EBA2E8A9977ED46E" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_OutsideDirectorWhoWasNotPreviouslyEmployeeMember" xlink:label="loc_vcyt_OutsideDirectorWhoWasNotPreviouslyEmployeeMember_30051CB26966DF0C7A64E8A9977EC553" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_626C66AA791A0D02EBA2E8A9977ED46E" xlink:to="loc_vcyt_OutsideDirectorWhoWasNotPreviouslyEmployeeMember_30051CB26966DF0C7A64E8A9977EC553" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_OutsideDirectorServingAsMemberOfBoardOfDirectorsForAtLeastSixMonthsMember" xlink:label="loc_vcyt_OutsideDirectorServingAsMemberOfBoardOfDirectorsForAtLeastSixMonthsMember_ED376646F3E0D4C11A62E8A9977F51C8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_626C66AA791A0D02EBA2E8A9977ED46E" xlink:to="loc_vcyt_OutsideDirectorServingAsMemberOfBoardOfDirectorsForAtLeastSixMonthsMember_ED376646F3E0D4C11A62E8A9977F51C8" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_OutsideDirectorMember" xlink:label="loc_vcyt_OutsideDirectorMember_207B5F50365658A2E78EE8A9977F7231" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_626C66AA791A0D02EBA2E8A9977ED46E" xlink:to="loc_vcyt_OutsideDirectorMember_207B5F50365658A2E78EE8A9977F7231" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_C729C4A968240E1A41B2E8A9977F722F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:to="loc_srt_RangeAxis_C729C4A968240E1A41B2E8A9977F722F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_7B1E52F07641C2EE4237E8A9977F4430" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_C729C4A968240E1A41B2E8A9977F722F" xlink:to="loc_srt_RangeMember_7B1E52F07641C2EE4237E8A9977F4430" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_44E61549BA127608E892E8A99780A851" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_7B1E52F07641C2EE4237E8A9977F4430" xlink:to="loc_srt_MinimumMember_44E61549BA127608E892E8A99780A851" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_D4E64E9549097F0ADC8DE8A997807687" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_7B1E52F07641C2EE4237E8A9977F4430" xlink:to="loc_srt_MaximumMember_D4E64E9549097F0ADC8DE8A997807687" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4B64F03E71A6F05EBDBBE8A9977879C1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_0D7650D1CC47B3AEC6C0E8A99780E0EF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_0D7650D1CC47B3AEC6C0E8A99780E0EF" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfVotingPowerOfAllClassesOfStock" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfVotingPowerOfAllClassesOfStock_33D1A3327E518180C3C6E8A997814CA8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfVotingPowerOfAllClassesOfStock_33D1A3327E518180C3C6E8A997814CA8" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardTermOfOptionsGrantedToEmployeesWhoOwnedSpecifiedPercentageOfClassOfStock" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardTermOfOptionsGrantedToEmployeesWhoOwnedSpecifiedPercentageOfClassOfStock_0DE8FCAEB98738A1E124E8A997811C94" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardTermOfOptionsGrantedToEmployeesWhoOwnedSpecifiedPercentageOfClassOfStock_0DE8FCAEB98738A1E124E8A997811C94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_DE3D679EB09B15DFE1C7E8A997811C34" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_DE3D679EB09B15DFE1C7E8A997811C34" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfStockPercentageForGrantsToPersonsWhoOwnedSpecifiedPercentageOfClassOfStock" xlink:label="loc_vcyt_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfStockPercentageForGrantsToPersonsWhoOwnedSpecifiedPercentageOfClassOfStock_EB1715CE40FD0E8EC3B3E8A997823480" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfStockPercentageForGrantsToPersonsWhoOwnedSpecifiedPercentageOfClassOfStock_EB1715CE40FD0E8EC3B3E8A997823480" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentageYearOne" xlink:label="loc_vcyt_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentageYearOne_8F02FE85EFBE28B2ED1DE8A99782126C" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentageYearOne_8F02FE85EFBE28B2ED1DE8A99782126C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_446705BD7B12D9EF6F09E8A997822EDB" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_446705BD7B12D9EF6F09E8A997822EDB" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_CommonStockCapitalAdditionalSharesReservedForFutureIssuance" xlink:label="loc_vcyt_CommonStockCapitalAdditionalSharesReservedForFutureIssuance_0FD5DDE3564D9527B642E8A99782C300" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_CommonStockCapitalAdditionalSharesReservedForFutureIssuance_0FD5DDE3564D9527B642E8A99782C300" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum_40B4BE53CA9F9871FD73E8A9978855D5" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum_40B4BE53CA9F9871FD73E8A9978855D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_293D3529C256395B8DC4E8A9978800AF" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_293D3529C256395B8DC4E8A9978800AF" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsInitialGrants" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsInitialGrants_CEE91A863348ADF7D73CE8A9978B4F36" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsInitialGrants_CEE91A863348ADF7D73CE8A9978B4F36" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAnnualGrants" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAnnualGrants_AF3E93A90F13039D18E9E8A9978BF8FE" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAnnualGrants_AF3E93A90F13039D18E9E8A9978BF8FE" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPeriodForWhichDirectorHasToServeAsBoardOfDirectorToReceiveGrantToPurchaseShares" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPeriodForWhichDirectorHasToServeAsBoardOfDirectorToReceiveGrantToPurchaseShares_599C4A7D64896F06EA77E8A9978C6754" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPeriodForWhichDirectorHasToServeAsBoardOfDirectorToReceiveGrantToPurchaseShares_599C4A7D64896F06EA77E8A9978C6754" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardExpirationPeriodAfterTermination" xlink:label="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardExpirationPeriodAfterTermination_A15A158D3AC91DEB1BC3E8A9978CFB33" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_3145E7B72C0A80F1CA5CE8A997800BE5" xlink:to="loc_vcyt_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardExpirationPeriodAfterTermination_A15A158D3AC91DEB1BC3E8A9978CFB33" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockIncentivePlansTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1F04AD2D92749F3B7DC1E8A997A18A1A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CDDA97676DC71CFC003DE8A997A1A640" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1F04AD2D92749F3B7DC1E8A997A18A1A" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CDDA97676DC71CFC003DE8A997A1A640" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_D0410A6EEAD1933B6E25E8A997A2F2B4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CDDA97676DC71CFC003DE8A997A1A640" xlink:to="loc_us-gaap_AwardTypeAxis_D0410A6EEAD1933B6E25E8A997A2F2B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_A1E9BB857BEB846CCC19E8A997A26720" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_D0410A6EEAD1933B6E25E8A997A2F2B4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_A1E9BB857BEB846CCC19E8A997A26720" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EmployeeAndNonEmployeeStockOptionExcludingBonusCompensationMember" xlink:label="loc_vcyt_EmployeeAndNonEmployeeStockOptionExcludingBonusCompensationMember_33CB48CF5944526B6E14E8A997A32343" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_A1E9BB857BEB846CCC19E8A997A26720" xlink:to="loc_vcyt_EmployeeAndNonEmployeeStockOptionExcludingBonusCompensationMember_33CB48CF5944526B6E14E8A997A32343" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EmployeeStockOptionExcludingBonusCompensationMember" xlink:label="loc_vcyt_EmployeeStockOptionExcludingBonusCompensationMember_99C6171327C6D0D129B3E8A997A394B1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_A1E9BB857BEB846CCC19E8A997A26720" xlink:to="loc_vcyt_EmployeeStockOptionExcludingBonusCompensationMember_99C6171327C6D0D129B3E8A997A394B1" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NonEmployeeStockOptionMember" xlink:label="loc_vcyt_NonEmployeeStockOptionMember_D42E6228D55E8DA4D075E8A997A4F758" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_A1E9BB857BEB846CCC19E8A997A26720" xlink:to="loc_vcyt_NonEmployeeStockOptionMember_D42E6228D55E8DA4D075E8A997A4F758" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockMember" xlink:label="loc_us-gaap_EmployeeStockMember_21BD10B3CD31B3790791E8A997A46C0E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_A1E9BB857BEB846CCC19E8A997A26720" xlink:to="loc_us-gaap_EmployeeStockMember_21BD10B3CD31B3790791E8A997A46C0E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_96A28130453DFCD4EEACE8A997A42E0C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CDDA97676DC71CFC003DE8A997A1A640" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_96A28130453DFCD4EEACE8A997A42E0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_1A209497B3A8C5D94A05E8A997A6E27B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_96A28130453DFCD4EEACE8A997A42E0C" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_1A209497B3A8C5D94A05E8A997A6E27B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_EAF0537D8A8D16762818E8A997A950F5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_96A28130453DFCD4EEACE8A997A42E0C" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_EAF0537D8A8D16762818E8A997A950F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_8DF4BC45D766FB33B8D4E8A997A9DF8C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_96A28130453DFCD4EEACE8A997A42E0C" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_8DF4BC45D766FB33B8D4E8A997A9DF8C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockholdersEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_0A5685DDCC44583E6ED6E8A997E656D8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_7C22EA3E895BFA6ACDD7E8A997E6425F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0A5685DDCC44583E6ED6E8A997E656D8" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_7C22EA3E895BFA6ACDD7E8A997E6425F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockholdersEquityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_0BE8CEEFCA7B66BA6EAE402FCF0D30DA" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfStockByClassTable" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_53AECB533EAAE666B16D402FCF0D1B38" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0BE8CEEFCA7B66BA6EAE402FCF0D30DA" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_53AECB533EAAE666B16D402FCF0D1B38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_6C5B09598B0E6D410DD8402FCF0E34CE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_53AECB533EAAE666B16D402FCF0D1B38" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_6C5B09598B0E6D410DD8402FCF0E34CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_EDE773B915D647A5FDDA402FCF0EDE63" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_6C5B09598B0E6D410DD8402FCF0E34CE" xlink:to="loc_us-gaap_EquityComponentDomain_EDE773B915D647A5FDDA402FCF0EDE63" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_16FC6DB6E809F330B12F402FCF0F9B0A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_EDE773B915D647A5FDDA402FCF0EDE63" xlink:to="loc_us-gaap_CommonStockMember_16FC6DB6E809F330B12F402FCF0F9B0A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_19A5ADAD3116B11A9212402FCF0F3A14" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_53AECB533EAAE666B16D402FCF0D1B38" xlink:to="loc_us-gaap_AwardTypeAxis_19A5ADAD3116B11A9212402FCF0F3A14" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_71E054FE064CCD35F3A1402FCF0F144C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_19A5ADAD3116B11A9212402FCF0F3A14" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_71E054FE064CCD35F3A1402FCF0F144C" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_EmployeeAndNonEmployeeStockOptionMember" xlink:label="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_9734F675ABC6916C0F51402FCF0F26FD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_71E054FE064CCD35F3A1402FCF0F144C" xlink:to="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_9734F675ABC6916C0F51402FCF0F26FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockMember" xlink:label="loc_us-gaap_EmployeeStockMember_E7CB2C7CA090760BE953402FCF101089" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_71E054FE064CCD35F3A1402FCF0F144C" xlink:to="loc_us-gaap_EmployeeStockMember_E7CB2C7CA090760BE953402FCF101089" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_EF5C745AEB19BBAD662D402FCF10B8AE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_53AECB533EAAE666B16D402FCF0D1B38" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_EF5C745AEB19BBAD662D402FCF10B8AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_805C5752D906103F3A16402FCF10324B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_EF5C745AEB19BBAD662D402FCF10B8AE" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_805C5752D906103F3A16402FCF10324B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OverAllotmentOptionMember" xlink:label="loc_us-gaap_OverAllotmentOptionMember_4C2AAE9B56B46D068847402FCF10B296" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_805C5752D906103F3A16402FCF10324B" xlink:to="loc_us-gaap_OverAllotmentOptionMember_4C2AAE9B56B46D068847402FCF10B296" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ClassOfStockLineItems" xlink:label="loc_us-gaap_ClassOfStockLineItems_B3CCEC7FF36BA81DE441402FCF101A64" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_53AECB533EAAE666B16D402FCF0D1B38" xlink:to="loc_us-gaap_ClassOfStockLineItems_B3CCEC7FF36BA81DE441402FCF101A64" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_CommonStockAbstract" xlink:label="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_B3CCEC7FF36BA81DE441402FCF101A64" xlink:to="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_9A7430A58BBCCCF1ACBA402FCF119FA8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_9A7430A58BBCCCF1ACBA402FCF119FA8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_60978349F52C5964768C402FCF119E7C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_60978349F52C5964768C402FCF119E7C" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_VotingRightsForEachShareOfStock" xlink:label="loc_vcyt_VotingRightsForEachShareOfStock_6C531437C05BEAFBE2BE402FCF11E6D2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_vcyt_VotingRightsForEachShareOfStock_6C531437C05BEAFBE2BE402FCF11E6D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DividendsPayableCurrentAndNoncurrent" xlink:label="loc_us-gaap_DividendsPayableCurrentAndNoncurrent_0E8B9B5173AB64280D8E402FCF11484E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_DividendsPayableCurrentAndNoncurrent_0E8B9B5173AB64280D8E402FCF11484E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_F43A207117648FA2CAC2402FCF110560" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_F43A207117648FA2CAC2402FCF110560" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_4BC1054D0FFB99701B1F402FCF1294C3" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_4BC1054D0FFB99701B1F402FCF1294C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_4EC442FC624F328D61C1402FCF12173D" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_4EC442FC624F328D61C1402FCF12173D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_DD24BDDBCC8334D908AF402FCF12901C" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_DD24BDDBCC8334D908AF402FCF12901C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockPricePerShare" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_CE6CBE0F5A198DEEE496402FCF128049" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_CE6CBE0F5A198DEEE496402FCF128049" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_A5619EE77F3D87B23341402FCF123257" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_A5619EE77F3D87B23341402FCF123257" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsOfStockIssuanceCosts" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_71D95DBF8139A88B2C48402FCF1261A5" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_71D95DBF8139A88B2C48402FCF1261A5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_79EB3FB6F63859172D26402FCF131704" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_79EB3FB6F63859172D26402FCF131704" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharesIssuedPricePerShare" xlink:label="loc_us-gaap_SharesIssuedPricePerShare_40B848B563A22541D4D4402FCF13522A" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_SharesIssuedPricePerShare_40B848B563A22541D4D4402FCF13522A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_02BBC241EEDA05F9DC6D402FCF13EAA7" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_7F1B268D239F71397CF4402FCF112FFB" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_02BBC241EEDA05F9DC6D402FCF13EAA7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockholdersEquityTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_6268A8B5BAF85C1ED949E8A997E2C36F" xlink:type="locator" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock" xlink:label="loc_vcyt_ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock_B88444D325A8C88569CAE8A997E2A7C0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_6268A8B5BAF85C1ED949E8A997E2C36F" xlink:to="loc_vcyt_ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock_B88444D325A8C88569CAE8A997E2A7C0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_6B4F8E9ACD5AF2445851E8A999D6A597" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_6E9E83F76A3C10C59F47E8A999D634DF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6B4F8E9ACD5AF2445851E8A999D6A597" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_6E9E83F76A3C10C59F47E8A999D634DF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesCreditRiskRestrictedCashAndAllowanceForDoubtfulAccountsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_9462CB951191DBBD05E249ADE1623BB2" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskTable" xlink:label="loc_us-gaap_ConcentrationRiskTable_E66154460DC813051A7F49ADE1623D0F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9462CB951191DBBD05E249ADE1623BB2" xlink:to="loc_us-gaap_ConcentrationRiskTable_E66154460DC813051A7F49ADE1623D0F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_22BD2220B4BFA85647EB49ADE162B96F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_E66154460DC813051A7F49ADE1623D0F" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_22BD2220B4BFA85647EB49ADE162B96F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EAC9812E6262E538115149ADE162C3B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_22BD2220B4BFA85647EB49ADE162B96F" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EAC9812E6262E538115149ADE162C3B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SalesRevenueNetMember" xlink:label="loc_us-gaap_SalesRevenueNetMember_7A4FE46E8738453652AF49ADE1637E2E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EAC9812E6262E538115149ADE162C3B6" xlink:to="loc_us-gaap_SalesRevenueNetMember_7A4FE46E8738453652AF49ADE1637E2E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsReceivableMember" xlink:label="loc_us-gaap_AccountsReceivableMember_3F98B698A4436A1DE06D49ADE16330AD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EAC9812E6262E538115149ADE162C3B6" xlink:to="loc_us-gaap_AccountsReceivableMember_3F98B698A4436A1DE06D49ADE16330AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_652445DC51EE608B287149ADE163CD13" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_E66154460DC813051A7F49ADE1623D0F" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_652445DC51EE608B287149ADE163CD13" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_B7B8B039AD526BC1F1A949ADE16323E0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_652445DC51EE608B287149ADE163CD13" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_B7B8B039AD526BC1F1A949ADE16323E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CustomerConcentrationRiskMember" xlink:label="loc_us-gaap_CustomerConcentrationRiskMember_486582BF374D036A2E5A49ADE1638EEB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_B7B8B039AD526BC1F1A949ADE16323E0" xlink:to="loc_us-gaap_CustomerConcentrationRiskMember_486582BF374D036A2E5A49ADE1638EEB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditConcentrationRiskMember" xlink:label="loc_us-gaap_CreditConcentrationRiskMember_3057F7A92191D229E3BF49ADE164CFC9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_B7B8B039AD526BC1F1A949ADE16323E0" xlink:to="loc_us-gaap_CreditConcentrationRiskMember_3057F7A92191D229E3BF49ADE164CFC9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MajorCustomersAxis" xlink:label="loc_srt_MajorCustomersAxis_315104023221823FE2FB49ADE164CD1A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_E66154460DC813051A7F49ADE1623D0F" xlink:to="loc_srt_MajorCustomersAxis_315104023221823FE2FB49ADE164CD1A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_NameOfMajorCustomerDomain" xlink:label="loc_srt_NameOfMajorCustomerDomain_8C63384E41CD0B047BEB49ADE1649378" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_315104023221823FE2FB49ADE164CD1A" xlink:to="loc_srt_NameOfMajorCustomerDomain_8C63384E41CD0B047BEB49ADE1649378" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_MedicareMember" xlink:label="loc_vcyt_MedicareMember_4EB3F58F763D21F3A67749ADE164BEF6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_8C63384E41CD0B047BEB49ADE1649378" xlink:to="loc_vcyt_MedicareMember_4EB3F58F763D21F3A67749ADE164BEF6" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_JohnsonandJohnsonServicesInc.Member" xlink:label="loc_vcyt_JohnsonandJohnsonServicesInc.Member_15381DC07AB53B7FFEAA49ADE1652FFC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_8C63384E41CD0B047BEB49ADE1649378" xlink:to="loc_vcyt_JohnsonandJohnsonServicesInc.Member_15381DC07AB53B7FFEAA49ADE1652FFC" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_UnitedHealthcareMember" xlink:label="loc_vcyt_UnitedHealthcareMember_C6B8BB1ECE06F82E075F49ADE165BC9E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_8C63384E41CD0B047BEB49ADE1649378" xlink:to="loc_vcyt_UnitedHealthcareMember_C6B8BB1ECE06F82E075F49ADE165BC9E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskLineItems" xlink:label="loc_us-gaap_ConcentrationRiskLineItems_91AD6FD8E2FDF020C06149ADE1655C1A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_E66154460DC813051A7F49ADE1623D0F" xlink:to="loc_us-gaap_ConcentrationRiskLineItems_91AD6FD8E2FDF020C06149ADE1655C1A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ConcentrationRiskAbstract" xlink:label="loc_vcyt_ConcentrationRiskAbstract_F06148D478CFBE38CF4F49ADE16520D5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_91AD6FD8E2FDF020C06149ADE1655C1A" xlink:to="loc_vcyt_ConcentrationRiskAbstract_F06148D478CFBE38CF4F49ADE16520D5" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited" xlink:label="loc_vcyt_NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited_3D1107B21FAA65CE096E49ADE165A9DF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ConcentrationRiskAbstract_F06148D478CFBE38CF4F49ADE16520D5" xlink:to="loc_vcyt_NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited_3D1107B21FAA65CE096E49ADE165A9DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_4B64EE189FE6852A6DFD49ADE1666833" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ConcentrationRiskAbstract_F06148D478CFBE38CF4F49ADE16520D5" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_4B64EE189FE6852A6DFD49ADE1666833" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndInvestmentsAbstract" xlink:label="loc_us-gaap_RestrictedCashAndInvestmentsAbstract_0C6D57D80CB68FE8845849ADE166D2D9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_91AD6FD8E2FDF020C06149ADE1655C1A" xlink:to="loc_us-gaap_RestrictedCashAndInvestmentsAbstract_0C6D57D80CB68FE8845849ADE166D2D9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_F02766F2E492BBA4058049ADE166F1DF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndInvestmentsAbstract_0C6D57D80CB68FE8845849ADE166D2D9" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_F02766F2E492BBA4058049ADE166F1DF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesDiagnosticDevelopmentAgreementWithJohnsonJohnsonDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_00EF9027FA5EC0F250A249BB0B01ADFD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable" xlink:label="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_522D3F8C7C74BCE3EDA749BB0B018FE8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_00EF9027FA5EC0F250A249BB0B01ADFD" xlink:to="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_522D3F8C7C74BCE3EDA749BB0B018FE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_CC09CAA23872CC69564A49BB0B0162FE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_522D3F8C7C74BCE3EDA749BB0B018FE8" xlink:to="loc_srt_ProductOrServiceAxis_CC09CAA23872CC69564A49BB0B0162FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_906C3CE3613AC6D056D849BB0B026382" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_CC09CAA23872CC69564A49BB0B0162FE" xlink:to="loc_srt_ProductsAndServicesDomain_906C3CE3613AC6D056D849BB0B026382" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ProvisionofDataMember" xlink:label="loc_vcyt_ProvisionofDataMember_7A152FE9FD51EE6751DE49BB0B022097" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_906C3CE3613AC6D056D849BB0B026382" xlink:to="loc_vcyt_ProvisionofDataMember_7A152FE9FD51EE6751DE49BB0B022097" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_FulfillmentofObligationsMember" xlink:label="loc_vcyt_FulfillmentofObligationsMember_E34D363DD9FB8E4319C349BB0B03AB3E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_906C3CE3613AC6D056D849BB0B026382" xlink:to="loc_vcyt_FulfillmentofObligationsMember_E34D363DD9FB8E4319C349BB0B03AB3E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MajorCustomersAxis" xlink:label="loc_srt_MajorCustomersAxis_3BC45E9B0273C6C0555849BB0B03DCF1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_522D3F8C7C74BCE3EDA749BB0B018FE8" xlink:to="loc_srt_MajorCustomersAxis_3BC45E9B0273C6C0555849BB0B03DCF1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_NameOfMajorCustomerDomain" xlink:label="loc_srt_NameOfMajorCustomerDomain_05B2095836D019C277AD49BB0B032F93" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_3BC45E9B0273C6C0555849BB0B03DCF1" xlink:to="loc_srt_NameOfMajorCustomerDomain_05B2095836D019C277AD49BB0B032F93" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_JohnsonandJohnsonServicesInc.Member" xlink:label="loc_vcyt_JohnsonandJohnsonServicesInc.Member_183102F73BEEBBD3CCEF49BB0B030AEB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_05B2095836D019C277AD49BB0B032F93" xlink:to="loc_vcyt_JohnsonandJohnsonServicesInc.Member_183102F73BEEBBD3CCEF49BB0B030AEB" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_Perceptav.2andNassaRiskMember" xlink:label="loc_vcyt_Perceptav.2andNassaRiskMember_90D6A9957D7BD9F9E0BB49BB0B03243C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_05B2095836D019C277AD49BB0B032F93" xlink:to="loc_vcyt_Perceptav.2andNassaRiskMember_90D6A9957D7BD9F9E0BB49BB0B03243C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EntityWideRevenueMajorCustomerLineItems" xlink:label="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_522D3F8C7C74BCE3EDA749BB0B018FE8" xlink:to="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_DevelopmentPrograms" xlink:label="loc_vcyt_DevelopmentPrograms_27E0D2E9A4A3B4E40DCF49BB0B049DF1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_vcyt_DevelopmentPrograms_27E0D2E9A4A3B4E40DCF49BB0B049DF1" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ContractAgreementReceivableForServices" xlink:label="loc_vcyt_ContractAgreementReceivableForServices_924E6FE01D1F820DFA2749BB0B04872C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_vcyt_ContractAgreementReceivableForServices_924E6FE01D1F820DFA2749BB0B04872C" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ContractAgreementConditionalAccountsReceivable" xlink:label="loc_vcyt_ContractAgreementConditionalAccountsReceivable_453D56CCF4B7B9F4DC3749BB0B042230" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_vcyt_ContractAgreementConditionalAccountsReceivable_453D56CCF4B7B9F4DC3749BB0B042230" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_TermContractAgreement" xlink:label="loc_vcyt_TermContractAgreement_3F6AC36F64AB72464D6349BB0B051BC5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_vcyt_TermContractAgreement_3F6AC36F64AB72464D6349BB0B051BC5" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ContractAgreementFeePercentageOfCashCollections" xlink:label="loc_vcyt_ContractAgreementFeePercentageOfCashCollections_4235D6AD5D5FCE727ABD49BB0B054D3F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_vcyt_ContractAgreementFeePercentageOfCashCollections_4235D6AD5D5FCE727ABD49BB0B054D3F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_A88E4F615203093E10C749BB0B053849" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_A88E4F615203093E10C749BB0B053849" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsReceivableGross" xlink:label="loc_us-gaap_AccountsReceivableGross_50DCE4A53BBABC316D7C49BB0B051151" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_us-gaap_AccountsReceivableGross_50DCE4A53BBABC316D7C49BB0B051151" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_C845E5576341EF26CB9D49BB0B05179D" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_6B56061B5E17154CD12849BB0B047D06" xlink:to="loc_us-gaap_ContractWithCustomerLiability_C845E5576341EF26CB9D49BB0B05179D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesIntangibleAssetsBonusAccrualsAndRevenueRecognitionDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_83D884DF9C5E39FC779C64B32EF8B622" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_83D884DF9C5E39FC779C64B32EF8B622" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MajorCustomersAxis" xlink:label="loc_srt_MajorCustomersAxis_DE63ECDC87E077F312F764B32EFBEAF2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_srt_MajorCustomersAxis_DE63ECDC87E077F312F764B32EFBEAF2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_NameOfMajorCustomerDomain" xlink:label="loc_srt_NameOfMajorCustomerDomain_DEC0EE5BE5C033513ABB64B32EFB3277" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_DE63ECDC87E077F312F764B32EFBEAF2" xlink:to="loc_srt_NameOfMajorCustomerDomain_DEC0EE5BE5C033513ABB64B32EFB3277" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_JohnsonandJohnsonServicesInc.Member" xlink:label="loc_vcyt_JohnsonandJohnsonServicesInc.Member_2CFD38EA68DCEBCE52CB64B32EFB4E44" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_DEC0EE5BE5C033513ABB64B32EFB3277" xlink:to="loc_vcyt_JohnsonandJohnsonServicesInc.Member_2CFD38EA68DCEBCE52CB64B32EFB4E44" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_57E0419E5C4CE91096A364B32EFC0CA3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_57E0419E5C4CE91096A364B32EFC0CA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_2B3F77D277759C85A86764B32EFC4343" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_57E0419E5C4CE91096A364B32EFC0CA3" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_2B3F77D277759C85A86764B32EFC4343" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductConcentrationRiskMember" xlink:label="loc_us-gaap_ProductConcentrationRiskMember_FDB601C6F71948E5A87464B32EFCB83F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_2B3F77D277759C85A86764B32EFC4343" xlink:to="loc_us-gaap_ProductConcentrationRiskMember_FDB601C6F71948E5A87464B32EFCB83F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditConcentrationRiskMember" xlink:label="loc_us-gaap_CreditConcentrationRiskMember_E419670D4085A39D9E1C64B32EFDAF84" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_2B3F77D277759C85A86764B32EFC4343" xlink:to="loc_us-gaap_CreditConcentrationRiskMember_E419670D4085A39D9E1C64B32EFDAF84" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_82E3E5ECAC14EE9D002064B32EFD20E9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_82E3E5ECAC14EE9D002064B32EFD20E9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EE93DDEE7BECCFABF1B864B32EFD1588" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_82E3E5ECAC14EE9D002064B32EFD20E9" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EE93DDEE7BECCFABF1B864B32EFD1588" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerProductAndServiceBenchmarkMember" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerProductAndServiceBenchmarkMember_FF10A53B715AB5215C0564B32EFD9624" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EE93DDEE7BECCFABF1B864B32EFD1588" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerProductAndServiceBenchmarkMember_FF10A53B715AB5215C0564B32EFD9624" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsReceivableMember" xlink:label="loc_us-gaap_AccountsReceivableMember_19ABB65D7E935EA487DB64B32EFE7728" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_EE93DDEE7BECCFABF1B864B32EFD1588" xlink:to="loc_us-gaap_AccountsReceivableMember_19ABB65D7E935EA487DB64B32EFE7728" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_DA9D9A8A6A3EE91FA13464B32EFE9DF0" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_srt_ProductOrServiceAxis_DA9D9A8A6A3EE91FA13464B32EFE9DF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_67952B544544642624D664B32EFE3669" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_DA9D9A8A6A3EE91FA13464B32EFE9DF0" xlink:to="loc_srt_ProductsAndServicesDomain_67952B544544642624D664B32EFE3669" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_TestingMember" xlink:label="loc_vcyt_TestingMember_0DF37BFFD739F105C47964B32EFEAA1F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_67952B544544642624D664B32EFE3669" xlink:to="loc_vcyt_TestingMember_0DF37BFFD739F105C47964B32EFEAA1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductMember" xlink:label="loc_us-gaap_ProductMember_140460DCAB4BE60CA3F064B32EFF42E3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_67952B544544642624D664B32EFE3669" xlink:to="loc_us-gaap_ProductMember_140460DCAB4BE60CA3F064B32EFF42E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ServiceMember" xlink:label="loc_us-gaap_ServiceMember_4D2862D91C48A541F10264B32EFFE7C8" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_67952B544544642624D664B32EFE3669" xlink:to="loc_us-gaap_ServiceMember_4D2862D91C48A541F10264B32EFFE7C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_2714E03E8FCB568AC7AA64B32EFF9CC5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_srt_RangeAxis_2714E03E8FCB568AC7AA64B32EFF9CC5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_9D4ABAAE7E3E9AE5C39C64B32EFF99F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_2714E03E8FCB568AC7AA64B32EFF9CC5" xlink:to="loc_srt_RangeMember_9D4ABAAE7E3E9AE5C39C64B32EFF99F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_EDE5B35134037322AC9264B32EFF79D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9D4ABAAE7E3E9AE5C39C64B32EFF99F1" xlink:to="loc_srt_MinimumMember_EDE5B35134037322AC9264B32EFF79D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_143554D900D4FECF253464B32F00CCA1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9D4ABAAE7E3E9AE5C39C64B32EFF99F1" xlink:to="loc_srt_MaximumMember_143554D900D4FECF253464B32F00CCA1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_0658A0895BE98CC53BDF64B32F001FDF" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_0658A0895BE98CC53BDF64B32F001FDF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_B1BFBD011B77C48BA3E064B32F005502" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_0658A0895BE98CC53BDF64B32F001FDF" xlink:to="loc_us-gaap_TypeOfAdoptionMember_B1BFBD011B77C48BA3E064B32F005502" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingStandardsUpdate201409Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201409Member_8B6814F3FF67FF314D8B64B32F00B189" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_B1BFBD011B77C48BA3E064B32F005502" xlink:to="loc_us-gaap_AccountingStandardsUpdate201409Member_8B6814F3FF67FF314D8B64B32F00B189" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_C8E73C693F9573874DBD64B32F009079" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_srt_CounterpartyNameAxis_C8E73C693F9573874DBD64B32F009079" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8FB6890D503B92B0E61B64B32F014C7F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_C8E73C693F9573874DBD64B32F009079" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8FB6890D503B92B0E61B64B32F014C7F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_BiopharmaceuticalCompanyMember" xlink:label="loc_vcyt_BiopharmaceuticalCompanyMember_357BF2A1B90AFD00BBCA64B32F012B1F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8FB6890D503B92B0E61B64B32F014C7F" xlink:to="loc_vcyt_BiopharmaceuticalCompanyMember_357BF2A1B90AFD00BBCA64B32F012B1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsNotesAndLoansReceivableLineItems" xlink:label="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_17FE8884CE9F52F774DB64B32EFAF965" xlink:to="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_C92EB5FDC237B9204E0964B32F01AA13" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_C92EB5FDC237B9204E0964B32F01AA13" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_400FD9DD8AB742B6AE8564B32F026385" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_400FD9DD8AB742B6AE8564B32F026385" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGrossAbstract" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_1AA65A5CA053F968241764B32F022C1C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_1AA65A5CA053F968241764B32F022C1C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_DF58BD975B9A0DAB3D2664B32F02355C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_1AA65A5CA053F968241764B32F022C1C" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_DF58BD975B9A0DAB3D2664B32F02355C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsFinitelived" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_E4F5D944B128C0BCAE5864B32F0298A6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_1AA65A5CA053F968241764B32F022C1C" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsFinitelived_E4F5D944B128C0BCAE5864B32F0298A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillImpairedAbstract" xlink:label="loc_us-gaap_GoodwillImpairedAbstract_087D6ABCD04B7DECC50064B32F02597A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_GoodwillImpairedAbstract_087D6ABCD04B7DECC50064B32F02597A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_9521901A60F37638B39A64B32F033B1A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillImpairedAbstract_087D6ABCD04B7DECC50064B32F02597A" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_9521901A60F37638B39A64B32F033B1A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueRecognitionAbstract" xlink:label="loc_us-gaap_RevenueRecognitionAbstract_D048D523E5E36EB4A2A364B32F03F954" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_RevenueRecognitionAbstract_D048D523E5E36EB4A2A364B32F03F954" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_RevenueRecognizedOnAccrualBasis" xlink:label="loc_vcyt_RevenueRecognizedOnAccrualBasis_945BDF63181F9592CA8E64B32F037919" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueRecognitionAbstract_D048D523E5E36EB4A2A364B32F03F954" xlink:to="loc_vcyt_RevenueRecognizedOnAccrualBasis_945BDF63181F9592CA8E64B32F037919" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_RevenueRecognizedOnAccrualBasisPercentage" xlink:label="loc_vcyt_RevenueRecognizedOnAccrualBasisPercentage_F3CC1825683BF02C83F464B3A38DEECB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueRecognitionAbstract_D048D523E5E36EB4A2A364B32F03F954" xlink:to="loc_vcyt_RevenueRecognizedOnAccrualBasisPercentage_F3CC1825683BF02C83F464B3A38DEECB" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_RevenueRecognizedReceivedInCash" xlink:label="loc_vcyt_RevenueRecognizedReceivedInCash_2552877FF55E8444DA2E64B32F035FEC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueRecognitionAbstract_D048D523E5E36EB4A2A364B32F03F954" xlink:to="loc_vcyt_RevenueRecognizedReceivedInCash_2552877FF55E8444DA2E64B32F035FEC" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_RevenueRecognizedReceivedInCashPercentage" xlink:label="loc_vcyt_RevenueRecognizedReceivedInCashPercentage_68C438DA88064F54825C64B332B00EE7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueRecognitionAbstract_D048D523E5E36EB4A2A364B32F03F954" xlink:to="loc_vcyt_RevenueRecognizedReceivedInCashPercentage_68C438DA88064F54825C64B332B00EE7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5DD7B90871A4268C86A464B32F0302B7" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueRecognitionAbstract_D048D523E5E36EB4A2A364B32F03F954" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5DD7B90871A4268C86A464B32F0302B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_B83A0044124C0744A37A64B32F042D4F" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_ContractWithCustomerLiability_B83A0044124C0744A37A64B32F042D4F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiabilityRevenueRecognized" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_7F99BFEAA0840C55624B64B32F04B878" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_7F99BFEAA0840C55624B64B32F04B878" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_769BE38F003415509D6464B32F04B498" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_OperatingIncomeLoss_769BE38F003415509D6464B32F04B498" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_6A684314D5C47F03BF7064B32F04082B" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_6A684314D5C47F03BF7064B32F04082B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueRemainingPerformanceObligation" xlink:label="loc_us-gaap_RevenueRemainingPerformanceObligation_6EA1F6BB40F48829ED1464B32F04B31D" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_us-gaap_RevenueRemainingPerformanceObligation_6EA1F6BB40F48829ED1464B32F04B31D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_RevenueRemainingPerformanceObligationAmountPerQuarter" xlink:label="loc_vcyt_RevenueRemainingPerformanceObligationAmountPerQuarter_BC5DF38A495B8400467864B32F04DC34" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_vcyt_RevenueRemainingPerformanceObligationAmountPerQuarter_BC5DF38A495B8400467864B32F04DC34" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_TermContractAgreement" xlink:label="loc_vcyt_TermContractAgreement_82129AF0AA466B8AFA6D64B32F043291" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_vcyt_TermContractAgreement_82129AF0AA466B8AFA6D64B32F043291" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_AutomaticRenewalPeriodContractAgreement" xlink:label="loc_vcyt_AutomaticRenewalPeriodContractAgreement_297E1104D020027D667464B32F051199" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_79FA37A8228228CAD0B064B32F01A640" xlink:to="loc_vcyt_AutomaticRenewalPeriodContractAgreement_297E1104D020027D667464B32F051199" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesLiquidityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_C86248B174BB44E9F382E8A999B074FF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfStockByClassTable" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_C86248B174BB44E9F382E8A999B074FF" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_E246FB6A10E7BE965099E8A999B1F2BC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_E246FB6A10E7BE965099E8A999B1F2BC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_AF9E6D21230AFC2DB9D7E8A999B1880C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_E246FB6A10E7BE965099E8A999B1F2BC" xlink:to="loc_us-gaap_EquityComponentDomain_AF9E6D21230AFC2DB9D7E8A999B1880C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_9E8D0E7FE93EEA58AD50E8A999B275C0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_AF9E6D21230AFC2DB9D7E8A999B1880C" xlink:to="loc_us-gaap_CommonStockMember_9E8D0E7FE93EEA58AD50E8A999B275C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_19BA44365AE195A90CBFE8A999B26404" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_19BA44365AE195A90CBFE8A999B26404" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4F6EE5AE019D8A564B8EE8A999B2FE51" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_19BA44365AE195A90CBFE8A999B26404" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4F6EE5AE019D8A564B8EE8A999B2FE51" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OverAllotmentOptionMember" xlink:label="loc_us-gaap_OverAllotmentOptionMember_E8978F44E95D3EC0ECE1E8A999B2E7AB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4F6EE5AE019D8A564B8EE8A999B2FE51" xlink:to="loc_us-gaap_OverAllotmentOptionMember_E8978F44E95D3EC0ECE1E8A999B2E7AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_F8421877E42874B062C3E8A999B3619C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:to="loc_us-gaap_CreditFacilityAxis_F8421877E42874B062C3E8A999B3619C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_88FDF8BF963490BA4FC2E8A999B3B933" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_F8421877E42874B062C3E8A999B3619C" xlink:to="loc_us-gaap_CreditFacilityDomain_88FDF8BF963490BA4FC2E8A999B3B933" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_C86574FF88A8C43CE9CBE8A999B32358" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_88FDF8BF963490BA4FC2E8A999B3B933" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_C86574FF88A8C43CE9CBE8A999B32358" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_0E9800FE4E0ABB67904FE8A999B33F84" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_0E9800FE4E0ABB67904FE8A999B33F84" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_21360F471269E1846B7DE8A999B4DD9C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_0E9800FE4E0ABB67904FE8A999B33F84" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_21360F471269E1846B7DE8A999B4DD9C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="loc_us-gaap_LineOfCreditMember_4F0A01A89451DCE70DF6E8A999B4F6D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_21360F471269E1846B7DE8A999B4DD9C" xlink:to="loc_us-gaap_LineOfCreditMember_4F0A01A89451DCE70DF6E8A999B4F6D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_AFE6C5EC60F799E44F8AE8A999B4B8FB" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_AFE6C5EC60F799E44F8AE8A999B4B8FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_744EA51D3366780E488BE8A999B452EF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_AFE6C5EC60F799E44F8AE8A999B4B8FB" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_744EA51D3366780E488BE8A999B452EF" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SiliconValleyBankMember" xlink:label="loc_vcyt_SiliconValleyBankMember_90B260E5A321F27DEBD9E8A999B52F52" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_744EA51D3366780E488BE8A999B452EF" xlink:to="loc_vcyt_SiliconValleyBankMember_90B260E5A321F27DEBD9E8A999B52F52" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_LiquidityLineItems" xlink:label="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_E57A4903873CFC545BF0E8A999B08886" xlink:to="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_2E6AAFE66C430B365B1FE8A999B59265" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_2E6AAFE66C430B365B1FE8A999B59265" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_AB7A162CA393D06401DDE8A999B52652" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_AB7A162CA393D06401DDE8A999B52652" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_F781A973C783E4BDB61EE8A999B65F98" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_F781A973C783E4BDB61EE8A999B65F98" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockPricePerShare" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_311A42412C53C1637001E8A999B6FFB0" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_311A42412C53C1637001E8A999B6FFB0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_2B309C4D39F6C58C3A27E8A999B6F820" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_2B309C4D39F6C58C3A27E8A999B6F820" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_C73EF9B9F9EC91B546A2E8A999B6C4AB" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_C73EF9B9F9EC91B546A2E8A999B6C4AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharesIssuedPricePerShare" xlink:label="loc_us-gaap_SharesIssuedPricePerShare_8C3A00CB8325DB5A2DD6E8A999B6C32F" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_SharesIssuedPricePerShare_8C3A00CB8325DB5A2DD6E8A999B6C32F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_BA8B71D126AD5AA647E6E8A999B67123" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_BA8B71D126AD5AA647E6E8A999B67123" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsOfStockIssuanceCosts" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_2F5BE7FA007B57ED84E9E8A999B7EC5C" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_2F5BE7FA007B57ED84E9E8A999B7EC5C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProceedsFromLongTermLinesOfCredit" xlink:label="loc_us-gaap_ProceedsFromLongTermLinesOfCredit_ABC421050684FE85E12FE8A999B79E7E" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_LiquidityLineItems_5AE983AD8D7708F2BDACE8A999B5F1B3" xlink:to="loc_us-gaap_ProceedsFromLongTermLinesOfCredit_ABC421050684FE85E12FE8A999B79E7E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_3A1E881F292FC2A067FDE8A999CA4347" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_3A1E881F292FC2A067FDE8A999CA4347" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="loc_us-gaap_UseOfEstimates_C1F2327C1E91CFDEF4EAE8A999CB864E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_UseOfEstimates_C1F2327C1E91CFDEF4EAE8A999CB864E" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ConcentrationsOfCreditAndOtherRisksAndUncertaintiesPolicyTextBlock" xlink:label="loc_vcyt_ConcentrationsOfCreditAndOtherRisksAndUncertaintiesPolicyTextBlock_8B5F2575459AE2890EC8E8A999CB8196" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_vcyt_ConcentrationsOfCreditAndOtherRisksAndUncertaintiesPolicyTextBlock_8B5F2575459AE2890EC8E8A999CB8196" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsUnrestrictedCashAndCashEquivalentsPolicy" xlink:label="loc_us-gaap_CashAndCashEquivalentsUnrestrictedCashAndCashEquivalentsPolicy_7CC9BDED219DEE001103E8A999CC9FDE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_CashAndCashEquivalentsUnrestrictedCashAndCashEquivalentsPolicy_7CC9BDED219DEE001103E8A999CC9FDE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy" xlink:label="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_C2908A0D930BD7B9CD31E8A999CDB9B3" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_C2908A0D930BD7B9CD31E8A999CDB9B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationsPolicy" xlink:label="loc_us-gaap_BusinessCombinationsPolicy_95208BB99FFA79821921E8A999CEFEEB" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_BusinessCombinationsPolicy_95208BB99FFA79821921E8A999CEFEEB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TradeAndOtherAccountsReceivablePolicy" xlink:label="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_08C5A0728674DC7EBCA6E8A999CEAEF2" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_08C5A0728674DC7EBCA6E8A999CEAEF2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_0169D58D92AE68654153E8A999CE0177" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_0169D58D92AE68654153E8A999CE0177" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IntangibleAssetsFiniteLivedPolicy" xlink:label="loc_us-gaap_IntangibleAssetsFiniteLivedPolicy_D75540A17E7B21DDDD1AE8A999CEFFAE" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_IntangibleAssetsFiniteLivedPolicy_D75540A17E7B21DDDD1AE8A999CEFFAE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsGoodwillPolicy" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsGoodwillPolicy_33CE596E690FB1D991ACE8A999CF9995" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsGoodwillPolicy_33CE596E690FB1D991ACE8A999CF9995" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy" xlink:label="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_2E2A8F953EF46964639AE8A999CF5AF8" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_2E2A8F953EF46964639AE8A999CF5AF8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_78A54E285BF48C186697E8A999CF554A" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_78A54E285BF48C186697E8A999CF554A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_D98C81995C7C74E4A166E8A999D05346" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_D98C81995C7C74E4A166E8A999D05346" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_3F6FD3E1BF147C5AACDFE8A999D07903" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_3F6FD3E1BF147C5AACDFE8A999D07903" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_06E12798EF8BBBFF1670E8A999D04334" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_06E12798EF8BBBFF1670E8A999D04334" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EarningsPerSharePolicyTextBlock" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_90B13B73FFD102B05F02E8A999D0C50C" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_90B13B73FFD102B05F02E8A999D0C50C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_C9016FA929821F80BE89E8A999D0B93D" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_F671A821951065B69C48E8A999CA37B9" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_C9016FA929821F80BE89E8A999D0B93D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesRecentAccountingPronouncementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_C4E199A248D561195255ED5114EAF60D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_9F684B82BFEAB6569404ED55AB304875" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_C4E199A248D561195255ED5114EAF60D" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_9F684B82BFEAB6569404ED55AB304875" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_F7E35784805B86596510ED55E78E7057" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_9F684B82BFEAB6569404ED55AB304875" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_F7E35784805B86596510ED55E78E7057" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_22169E67ABC4FD909F54ED55E78F3921" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_F7E35784805B86596510ED55E78E7057" xlink:to="loc_us-gaap_TypeOfAdoptionMember_22169E67ABC4FD909F54ED55E78F3921" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingStandardsUpdate201602Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201602Member_E6C9E268D2517A724D98ED561BFCF0F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_22169E67ABC4FD909F54ED55E78F3921" xlink:to="loc_us-gaap_AccountingStandardsUpdate201602Member_E6C9E268D2517A724D98ED561BFCF0F4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_CDD274955842A525518AED55AB316F28" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_9F684B82BFEAB6569404ED55AB304875" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_CDD274955842A525518AED55AB316F28" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_D8B731BDBBDCF80F03F5ED5261C6384A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_CDD274955842A525518AED55AB316F28" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_D8B731BDBBDCF80F03F5ED5261C6384A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_829F4E53B8DECD157545ED535E9D7E27" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_CDD274955842A525518AED55AB316F28" xlink:to="loc_us-gaap_ContractWithCustomerLiability_829F4E53B8DECD157545ED535E9D7E27" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="loc_us-gaap_OperatingLeaseLiability_09AD324E1F3A34C0324FED53F6E44396" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_CDD274955842A525518AED55AB316F28" xlink:to="loc_us-gaap_OperatingLeaseLiability_09AD324E1F3A34C0324FED53F6E44396" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAsset" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAsset_FD3B3C8352368BAA0D98ED54D38DE7CF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_CDD274955842A525518AED55AB316F28" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAsset_FD3B3C8352368BAA0D98ED54D38DE7CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="loc_us-gaap_FinanceLeaseLiability_29DB2CF46866DC982A12ED54522D0753" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_CDD274955842A525518AED55AB316F28" xlink:to="loc_us-gaap_FinanceLeaseLiability_29DB2CF46866DC982A12ED54522D0753" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/SummaryOfSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_27A3460CB1FE63F9952349ADE1B5B763" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskTable" xlink:label="loc_us-gaap_ConcentrationRiskTable_F945F5065642BD04775549ADE1B59AE9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_27A3460CB1FE63F9952349ADE1B5B763" xlink:to="loc_us-gaap_ConcentrationRiskTable_F945F5065642BD04775549ADE1B59AE9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_AEB51D25AE18541F6D5349ADE1B5802E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_F945F5065642BD04775549ADE1B59AE9" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_AEB51D25AE18541F6D5349ADE1B5802E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_9C75CC2F721F4A33BCE749ADE1B6D0E5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_AEB51D25AE18541F6D5349ADE1B5802E" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_9C75CC2F721F4A33BCE749ADE1B6D0E5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CustomerConcentrationRiskMember" xlink:label="loc_us-gaap_CustomerConcentrationRiskMember_1072ED0F3AE42901D4D649ADE1B60AED" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_9C75CC2F721F4A33BCE749ADE1B6D0E5" xlink:to="loc_us-gaap_CustomerConcentrationRiskMember_1072ED0F3AE42901D4D649ADE1B60AED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditConcentrationRiskMember" xlink:label="loc_us-gaap_CreditConcentrationRiskMember_6EF17EFBFCB0FB5922E449ADE1B66228" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_9C75CC2F721F4A33BCE749ADE1B6D0E5" xlink:to="loc_us-gaap_CreditConcentrationRiskMember_6EF17EFBFCB0FB5922E449ADE1B66228" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_68441DCD38798DC9C0DB49ADE1B697CB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_F945F5065642BD04775549ADE1B59AE9" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_68441DCD38798DC9C0DB49ADE1B697CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_64E936DFC5BDB4B9C6C649ADE1B7E97D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_68441DCD38798DC9C0DB49ADE1B697CB" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_64E936DFC5BDB4B9C6C649ADE1B7E97D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_SalesRevenueGrossMember" xlink:label="loc_vcyt_SalesRevenueGrossMember_ABF54C3EAA33F465F7E649ADE1B76861" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_64E936DFC5BDB4B9C6C649ADE1B7E97D" xlink:to="loc_vcyt_SalesRevenueGrossMember_ABF54C3EAA33F465F7E649ADE1B76861" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsReceivableMember" xlink:label="loc_us-gaap_AccountsReceivableMember_E123F1AB659E2A6C3A6049ADE1B75983" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_64E936DFC5BDB4B9C6C649ADE1B7E97D" xlink:to="loc_us-gaap_AccountsReceivableMember_E123F1AB659E2A6C3A6049ADE1B75983" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ConcentrationRiskLineItems" xlink:label="loc_us-gaap_ConcentrationRiskLineItems_5D57E1E664F50D0330A549ADE1B74CDA" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_F945F5065642BD04775549ADE1B59AE9" xlink:to="loc_us-gaap_ConcentrationRiskLineItems_5D57E1E664F50D0330A549ADE1B74CDA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock" xlink:label="loc_us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock_BF05B622A72497BC93A449ADE1B75068" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_5D57E1E664F50D0330A549ADE1B74CDA" xlink:to="loc_us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock_BF05B622A72497BC93A449ADE1B75068" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenuesAbstract" xlink:label="loc_us-gaap_RevenuesAbstract_2CA393F3C29E43EBE5BC49ADE1B81745" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_5D57E1E664F50D0330A549ADE1B74CDA" xlink:to="loc_us-gaap_RevenuesAbstract_2CA393F3C29E43EBE5BC49ADE1B81745" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock" xlink:label="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_04ED8C4DFC797384170449E24E8C640E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_2CA393F3C29E43EBE5BC49ADE1B81745" xlink:to="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_04ED8C4DFC797384170449E24E8C640E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ThyroidCytopathologyPartners" xlink:type="extended">
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ServicesAgreementAbstract" xlink:label="loc_vcyt_ServicesAgreementAbstract_CE20E184EC7A6639A910E8A996D76F23" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermContractsOrProgramsDisclosureTextBlock" xlink:label="loc_us-gaap_LongTermContractsOrProgramsDisclosureTextBlock_59876F79745E7753847CE8A996D7F7B5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ServicesAgreementAbstract_CE20E184EC7A6639A910E8A996D76F23" xlink:to="loc_us-gaap_LongTermContractsOrProgramsDisclosureTextBlock_59876F79745E7753847CE8A996D7F7B5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ThyroidCytopathologyPartnersDetails" xlink:type="extended">
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_ServicesAgreementAbstract" xlink:label="loc_vcyt_ServicesAgreementAbstract_7B13B758D689509EF4B0E8A996D1040D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfVariableInterestEntitiesTable" xlink:label="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_382C854AA8C2AD157F73E8A996D11ED2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ServicesAgreementAbstract_7B13B758D689509EF4B0E8A996D1040D" xlink:to="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_382C854AA8C2AD157F73E8A996D11ED2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis" xlink:label="loc_us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis_86D4BBBE773B830A78BBE8A996D16EA4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_382C854AA8C2AD157F73E8A996D11ED2" xlink:to="loc_us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis_86D4BBBE773B830A78BBE8A996D16EA4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ClassificationOfVariableInterestEntityDomain" xlink:label="loc_us-gaap_ClassificationOfVariableInterestEntityDomain_FAB26F82F11CBDC30427E8A996D20707" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis_86D4BBBE773B830A78BBE8A996D16EA4" xlink:to="loc_us-gaap_ClassificationOfVariableInterestEntityDomain_FAB26F82F11CBDC30427E8A996D20707" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember" xlink:label="loc_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember_A4478FBB3AC76695FCD6E8A996D24EBC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassificationOfVariableInterestEntityDomain_FAB26F82F11CBDC30427E8A996D20707" xlink:to="loc_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember_A4478FBB3AC76695FCD6E8A996D24EBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_VariableInterestEntityLineItems" xlink:label="loc_us-gaap_VariableInterestEntityLineItems_314EEF975E3FA8EF3867E8A996D214D3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_382C854AA8C2AD157F73E8A996D11ED2" xlink:to="loc_us-gaap_VariableInterestEntityLineItems_314EEF975E3FA8EF3867E8A996D214D3" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20191231.xsd#vcyt_OtherIncomeRentReimbursement" xlink:label="loc_vcyt_OtherIncomeRentReimbursement_DC21978E840FEA79B4BBE8A996D4C93F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_314EEF975E3FA8EF3867E8A996D214D3" xlink:to="loc_vcyt_OtherIncomeRentReimbursement_DC21978E840FEA79B4BBE8A996D4C93F" xlink:type="arc" />
  </link:presentationLink>
</link:linkbase>
