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  <xsd:element id="vcyt_DebtInstrumentNumberOfInstallments" name="DebtInstrumentNumberOfInstallments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodFive" name="DebtInstrumentPenaltyPercentageOnPrepaymentPeriodFive" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodFour" name="DebtInstrumentPenaltyPercentageOnPrepaymentPeriodFour" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodOne" name="DebtInstrumentPenaltyPercentageOnPrepaymentPeriodOne" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodThree" name="DebtInstrumentPenaltyPercentageOnPrepaymentPeriodThree" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_DebtInstrumentPenaltyPercentageOnPrepaymentPeriodTwo" name="DebtInstrumentPenaltyPercentageOnPrepaymentPeriodTwo" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_DebtInstrumentPrepaymentAmountExcessMultiple" name="DebtInstrumentPrepaymentAmountExcessMultiple" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vcyt_DeferredStockOfferingCosts" name="DeferredStockOfferingCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_DocumentAndEntityInformationAbstract" name="DocumentAndEntityInformationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_EmployeeAndNonEmployeeStockOptionMember" name="EmployeeAndNonEmployeeStockOptionMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_GenzymeCorporationMember" name="GenzymeCorporationMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember" name="HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_HeadquartersAndLaboratoryFacilitySouthSanFranciscoMember" name="HeadquartersAndLaboratoryFacilitySouthSanFranciscoMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent" name="IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_InitialTermLoanMember" name="InitialTermLoanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_InterestExpenseandPrepaymentPenalty" name="InterestExpenseandPrepaymentPenalty" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_LaboratoryFacilitiesAustinTexasMember" name="LaboratoryFacilitiesAustinTexasMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_LesseeLeasingArrangementsOperatingLeasesSpaceLeased" name="LesseeLeasingArrangementsOperatingLeasesSpaceLeased" nillable="true" substitutionGroup="xbrli:item" type="num:areaItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_LongtermDebtMaturitiesRepaymentsofPrincipalinYearSix" name="LongtermDebtMaturitiesRepaymentsofPrincipalinYearSix" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="vcyt_MedicareMember" name="MedicareMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited" name="NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="vcyt_NumberOfTermLoans" name="NumberOfTermLoans" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="vcyt_OtherIncomeRentReimbursement" name="OtherIncomeRentReimbursement" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vcyt_PaymentOfEndOfTermObligation" name="PaymentOfEndOfTermObligation" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vcyt_PrepaymentPenalty" name="PrepaymentPenalty" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_PurchaseObligationAbstract" name="PurchaseObligationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_RevenuePercent" name="RevenuePercent" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_RevenueRecognizedOnAccrualBasis" name="RevenueRecognizedOnAccrualBasis" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vcyt_RevenueRecognizedOnAccrualBasisPercentage" name="RevenueRecognizedOnAccrualBasisPercentage" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_RevenueRecognizedReceivedInCash" name="RevenueRecognizedReceivedInCash" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vcyt_RevenueRecognizedReceivedInCashPercentage" name="RevenueRecognizedReceivedInCashPercentage" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_SalesRevenueGrossMember" name="SalesRevenueGrossMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock" name="ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_ScheduleOfRevenueRecognitionCashAndAccrualBasisTableTextBlock" name="ScheduleOfRevenueRecognitionCashAndAccrualBasisTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_SecondTermLoanMember" name="SecondTermLoanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_ServicesAgreementAbstract" name="ServicesAgreementAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_TermLoanMember" name="TermLoanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_TermOfDebtWithEqualQuarterlyInstallments" name="TermOfDebtWithEqualQuarterlyInstallments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="vcyt_TestingAndEvaluationServicesExpense" name="TestingAndEvaluationServicesExpense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_UnitedHealthcareMember" name="UnitedHealthcareMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vcyt_VisiumMember" name="VisiumMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
</xsd:schema>
