<?xml version="1.0" encoding="US-ASCII"?>
<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.veracyte.com/role/AccruedLiabilities" xlink:href="vcyt-20190630.xsd#AccruedLiabilities" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/AccruedLiabilitiesDetails" xlink:href="vcyt-20190630.xsd#AccruedLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/AccruedLiabilitiesTables" xlink:href="vcyt-20190630.xsd#AccruedLiabilitiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CommitmentsAndContingencies" xlink:href="vcyt-20190630.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CommitmentsAndContingenciesFinanceLeaseDetails" xlink:href="vcyt-20190630.xsd#CommitmentsAndContingenciesFinanceLeaseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CommitmentsAndContingenciesOperatingLeaseDetails" xlink:href="vcyt-20190630.xsd#CommitmentsAndContingenciesOperatingLeaseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CommitmentsAndContingenciesTables" xlink:href="vcyt-20190630.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CondensedBalanceSheets" xlink:href="vcyt-20190630.xsd#CondensedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CondensedBalanceSheetsParenthetical" xlink:href="vcyt-20190630.xsd#CondensedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CondensedStatementsOfCashFlows" xlink:href="vcyt-20190630.xsd#CondensedStatementsOfCashFlows" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CondensedStatementsOfOperationsAndComprehensiveLoss" xlink:href="vcyt-20190630.xsd#CondensedStatementsOfOperationsAndComprehensiveLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CondensedStatementsOfStockholdersEquity" xlink:href="vcyt-20190630.xsd#CondensedStatementsOfStockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/CondensedStatementsOfStockholdersEquityParenthetical" xlink:href="vcyt-20190630.xsd#CondensedStatementsOfStockholdersEquityParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/Debt" xlink:href="vcyt-20190630.xsd#Debt" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtDebtObligationForBorrowingsDetails" xlink:href="vcyt-20190630.xsd#DebtDebtObligationForBorrowingsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtNarrativeDetails" xlink:href="vcyt-20190630.xsd#DebtNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DebtTables" xlink:href="vcyt-20190630.xsd#DebtTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/DocumentAndEntityInformation" xlink:href="vcyt-20190630.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/FairValueMeasurements" xlink:href="vcyt-20190630.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/FairValueMeasurementsDetails" xlink:href="vcyt-20190630.xsd#FairValueMeasurementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxes" xlink:href="vcyt-20190630.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/IncomeTaxesDetails" xlink:href="vcyt-20190630.xsd#IncomeTaxesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/NetLossPerCommonShare" xlink:href="vcyt-20190630.xsd#NetLossPerCommonShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/NetLossPerCommonShareDetails" xlink:href="vcyt-20190630.xsd#NetLossPerCommonShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/NetLossPerCommonShareTables" xlink:href="vcyt-20190630.xsd#NetLossPerCommonShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusiness" xlink:href="vcyt-20190630.xsd#OrganizationAndDescriptionOfBusiness" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessCreditRiskDetails" xlink:href="vcyt-20190630.xsd#OrganizationAndDescriptionOfBusinessCreditRiskDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessNarrativeDetails" xlink:href="vcyt-20190630.xsd#OrganizationAndDescriptionOfBusinessNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessPolicies" xlink:href="vcyt-20190630.xsd#OrganizationAndDescriptionOfBusinessPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessTables" xlink:href="vcyt-20190630.xsd#OrganizationAndDescriptionOfBusinessTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockholdersEquity" xlink:href="vcyt-20190630.xsd#StockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockholdersEquityDetails" xlink:href="vcyt-20190630.xsd#StockholdersEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/StockholdersEquityTables" xlink:href="vcyt-20190630.xsd#StockholdersEquityTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ThyroidCytopathologyPartners" xlink:href="vcyt-20190630.xsd#ThyroidCytopathologyPartners" xlink:type="simple" />
  <link:roleRef roleURI="http://www.veracyte.com/role/ThyroidCytopathologyPartnersDetails" xlink:href="vcyt-20190630.xsd#ThyroidCytopathologyPartnersDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <link:presentationLink xlink:role="http://www.veracyte.com/role/AccruedLiabilities" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_8AA617B9E8DA9A360AB81B3B3FCA07F2" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_52C9B683731C3198C2AA1B3B3FCA47F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_8AA617B9E8DA9A360AB81B3B3FCA07F2" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_52C9B683731C3198C2AA1B3B3FCA47F1" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/AccruedLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_E68B01306B567E98CAF81B3B3FBAC906" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_606F0E6658E32DBC0BAE1B3B3FBA6E7F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_E68B01306B567E98CAF81B3B3FBAC906" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_606F0E6658E32DBC0BAE1B3B3FBA6E7F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_7477474912E06D314E0A1B3B3FBA2F96" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_E68B01306B567E98CAF81B3B3FBAC906" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_7477474912E06D314E0A1B3B3FBA2F96" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_BFF49D4183C80FEF5AFE1B3B3FBA2AC5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_E68B01306B567E98CAF81B3B3FBAC906" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_BFF49D4183C80FEF5AFE1B3B3FBA2AC5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/AccruedLiabilitiesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_5E725E1636605630BE5C1B3B3FC24B12" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_C0B722CDC57FE1A6BEDD1B3B3FC27B3C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_5E725E1636605630BE5C1B3B3FC24B12" xlink:to="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_C0B722CDC57FE1A6BEDD1B3B3FC27B3C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CommitmentsAndContingencies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_4BFDF05DA8F7BE65A05A1B3B3F91289C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_8A26C63982C2E864A5941B3B3F92608E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_4BFDF05DA8F7BE65A05A1B3B3F91289C" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_8A26C63982C2E864A5941B3B3F92608E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CommitmentsAndContingenciesFinanceLeaseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3F813F26C4B904497B711B3B3F60BA8F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="loc_us-gaap_FinanceLeaseLiability_B6A7BAFB2ADA05E0744C1B3B3F60F53D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3F813F26C4B904497B711B3B3F60BA8F" xlink:to="loc_us-gaap_FinanceLeaseLiability_B6A7BAFB2ADA05E0744C1B3B3F60F53D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_FinanceLeaseUpfrontPayment" xlink:label="loc_vcyt_FinanceLeaseUpfrontPayment_8BC70CFB6F03559E37CB1B3B3F60DB89" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3F813F26C4B904497B711B3B3F60BA8F" xlink:to="loc_vcyt_FinanceLeaseUpfrontPayment_8BC70CFB6F03559E37CB1B3B3F60DB89" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_8E4E5B3D26BA9DDF733F1B3B3F607232" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3F813F26C4B904497B711B3B3F60BA8F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_8E4E5B3D26BA9DDF733F1B3B3F607232" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_B29AB1D8AC711F429D381B3B3F61A7F9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3F813F26C4B904497B711B3B3F60BA8F" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_B29AB1D8AC711F429D381B3B3F61A7F9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CommitmentsAndContingenciesOperatingLeaseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_BB03D20A6D63664C1B9F1B3B3F7C23A2" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfOperatingLeasedAssetsTable" xlink:label="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_6B2E9182966057C6B0A71B3B3F7C61F1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_BB03D20A6D63664C1B9F1B3B3F7C23A2" xlink:to="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_6B2E9182966057C6B0A71B3B3F7C61F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseArrangementTypeAxis" xlink:label="loc_us-gaap_LeaseArrangementTypeAxis_2A8093FF4DB661AC9CA41B3B3F7C0DE5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_6B2E9182966057C6B0A71B3B3F7C61F1" xlink:to="loc_us-gaap_LeaseArrangementTypeAxis_2A8093FF4DB661AC9CA41B3B3F7C0DE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseArrangementTypeDomain" xlink:label="loc_us-gaap_LeaseArrangementTypeDomain_46A8BB56DCF1F23C1A0F1B3B3F7D4C34" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeAxis_2A8093FF4DB661AC9CA41B3B3F7C0DE5" xlink:to="loc_us-gaap_LeaseArrangementTypeDomain_46A8BB56DCF1F23C1A0F1B3B3F7D4C34" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember" xlink:label="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_3DD0847EC9A358BDFCE41B3B3F7D10BC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeDomain_46A8BB56DCF1F23C1A0F1B3B3F7D4C34" xlink:to="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_3DD0847EC9A358BDFCE41B3B3F7D10BC" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_LaboratoryFacilitiesAustinTexasMember" xlink:label="loc_vcyt_LaboratoryFacilitiesAustinTexasMember_B1EF600138B13835D63F1B3B3F7D3FCE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeDomain_46A8BB56DCF1F23C1A0F1B3B3F7D4C34" xlink:to="loc_vcyt_LaboratoryFacilitiesAustinTexasMember_B1EF600138B13835D63F1B3B3F7D3FCE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_CE67C4A73B3C35664C501B3B3F7D19AC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_6B2E9182966057C6B0A71B3B3F7C61F1" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_CE67C4A73B3C35664C501B3B3F7D19AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_72827F9251A8402A78E91B3B3F7E8B23" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_CE67C4A73B3C35664C501B3B3F7D19AC" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_72827F9251A8402A78E91B3B3F7E8B23" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherNoncurrentAssetsMember" xlink:label="loc_us-gaap_OtherNoncurrentAssetsMember_FAF75E9527C66D427EE71B3B3F7E8251" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_72827F9251A8402A78E91B3B3F7E8B23" xlink:to="loc_us-gaap_OtherNoncurrentAssetsMember_FAF75E9527C66D427EE71B3B3F7E8251" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasedAssetsLineItems" xlink:label="loc_us-gaap_OperatingLeasedAssetsLineItems_E4975C0AD1ADADD8C6501B3B3F7E2429" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfOperatingLeasedAssetsTable_6B2E9182966057C6B0A71B3B3F7C61F1" xlink:to="loc_us-gaap_OperatingLeasedAssetsLineItems_E4975C0AD1ADADD8C6501B3B3F7E2429" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_LesseeLeasingArrangementsOperatingLeasesSpaceLeased" xlink:label="loc_vcyt_LesseeLeasingArrangementsOperatingLeasesSpaceLeased_EFCE71348C01E30BDF681B3B3F7E7629" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_E4975C0AD1ADADD8C6501B3B3F7E2429" xlink:to="loc_vcyt_LesseeLeasingArrangementsOperatingLeasesSpaceLeased_EFCE71348C01E30BDF681B3B3F7E7629" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SecurityDeposit" xlink:label="loc_us-gaap_SecurityDeposit_9048F7C1E2FAFA91858F1B3B3F7F7D1B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_E4975C0AD1ADADD8C6501B3B3F7E2429" xlink:to="loc_us-gaap_SecurityDeposit_9048F7C1E2FAFA91858F1B3B3F7F7D1B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseDiscountRate" xlink:label="loc_us-gaap_LesseeOperatingLeaseDiscountRate_4BCF5E79AAE03A6018DF1B3B3F7F0F09" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_E4975C0AD1ADADD8C6501B3B3F7E2429" xlink:to="loc_us-gaap_LesseeOperatingLeaseDiscountRate_4BCF5E79AAE03A6018DF1B3B3F7F0F09" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_E4975C0AD1ADADD8C6501B3B3F7E2429" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_E5C5E1095FFFEA9415581B3B3F7FAFE0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_E5C5E1095FFFEA9415581B3B3F7FAFE0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_DC448EA455C2E1861EEF1B3B3F7F167B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_DC448EA455C2E1861EEF1B3B3F7F167B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_AA9D3BD67AF1FC3E41CE1B3B3F80FE0E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_AA9D3BD67AF1FC3E41CE1B3B3F80FE0E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_DD26B309CAEA36456EB21B3B3F803FA4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_DD26B309CAEA36456EB21B3B3F803FA4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_4D383F8546A9140107C81B3B3F804C85" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_4D383F8546A9140107C81B3B3F804C85" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_25B697D7376F00AD6CEE1B3B3F80BB11" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_25B697D7376F00AD6CEE1B3B3F80BB11" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0D7AEC5FE22365DEEF5D1B3B3F8047D4" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueAbstract_4E0B9A5D96F2B2A06C601B3B3F7F1915" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0D7AEC5FE22365DEEF5D1B3B3F8047D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesRentExpenseNet" xlink:label="loc_us-gaap_OperatingLeasesRentExpenseNet_F7F4235FA7A0D752B95A1B3B3F8078FD" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLeasedAssetsLineItems_E4975C0AD1ADADD8C6501B3B3F7E2429" xlink:to="loc_us-gaap_OperatingLeasesRentExpenseNet_F7F4235FA7A0D752B95A1B3B3F8078FD" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CommitmentsAndContingenciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3258A6708ED8CD6C28541B3B3F892508" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_FDDED6F64CEC71EDF3851B3B3F8AEA4B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3258A6708ED8CD6C28541B3B3F892508" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_FDDED6F64CEC71EDF3851B3B3F8AEA4B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CondensedBalanceSheets" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_4FADA1EF8149BC6E27B71B3B40638350" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_4FADA1EF8149BC6E27B71B3B40638350" xlink:to="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaap_AssetsCurrentAbstract_A5F915C0F0E49123C8731B3B4064C744" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_AssetsCurrentAbstract_A5F915C0F0E49123C8731B3B4064C744" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_391AB38C3716C1F170151B3B4064B9A4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_A5F915C0F0E49123C8731B3B4064C744" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_391AB38C3716C1F170151B3B4064B9A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_4703EA86969B1CB246A41B3B4064E6DC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_A5F915C0F0E49123C8731B3B4064C744" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_4703EA86969B1CB246A41B3B4064E6DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InventoryNet" xlink:label="loc_us-gaap_InventoryNet_88B2E2E68FEB0979C8B51B3B40643FD0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_A5F915C0F0E49123C8731B3B4064C744" xlink:to="loc_us-gaap_InventoryNet_88B2E2E68FEB0979C8B51B3B40643FD0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_F40929609B9CE9C130221B3B406505AF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_A5F915C0F0E49123C8731B3B4064C744" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_F40929609B9CE9C130221B3B406505AF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_0EA833C0F8931E9125931B3B40656372" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_A5F915C0F0E49123C8731B3B4064C744" xlink:to="loc_us-gaap_AssetsCurrent_0EA833C0F8931E9125931B3B40656372" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_621FA69DC9577EAF52F51B3B4065D051" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_621FA69DC9577EAF52F51B3B4065D051" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAsset" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAsset_3BA4E9FF50A395E8F7A51B3B406561EB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAsset_3BA4E9FF50A395E8F7A51B3B406561EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_19CD104A0DDAD3F7ABCF1B3B40651090" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_19CD104A0DDAD3F7ABCF1B3B40651090" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_C81E078E9AEF3B0F834C1B3B406539FB" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_C81E078E9AEF3B0F834C1B3B406539FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_F69657CDB26077582BA81B3B4066C80F" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_Goodwill_F69657CDB26077582BA81B3B4066C80F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_105BCF1F7B91BAFB99431B3B40660BBA" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_105BCF1F7B91BAFB99431B3B40660BBA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_B94B24171FE77A530E681B3B406657D4" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_B94B24171FE77A530E681B3B406657D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_B08F090A075FD18933BE1B3B406687BF" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_5500DEA5103EDD7FFD091B3B4063256E" xlink:to="loc_us-gaap_Assets_B08F090A075FD18933BE1B3B406687BF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_4FADA1EF8149BC6E27B71B3B40638350" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaap_AccountsPayableCurrent_45F2592BA3331C5E641B1B3B4067AF1C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:to="loc_us-gaap_AccountsPayableCurrent_45F2592BA3331C5E641B1B3B4067AF1C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_EF61D1465EC722C202DB1B3B4067EAE7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_EF61D1465EC722C202DB1B3B4067EAE7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_DD721BC209227EEA39A71B3B4067C364" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:to="loc_us-gaap_LongTermDebtCurrent_DD721BC209227EEA39A71B3B4067C364" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeaseLiabilityCurrent" xlink:label="loc_us-gaap_FinanceLeaseLiabilityCurrent_F593E8145FA05A108B8B1B3B4067D5F9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:to="loc_us-gaap_FinanceLeaseLiabilityCurrent_F593E8145FA05A108B8B1B3B4067D5F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_5E1520616882BB9386D81B3B40680D7C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_5E1520616882BB9386D81B3B40680D7C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_D879C7865927B80F92001B3B4068EDD2" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_FFE9F7BBBB07274B2ABF1B3B4067B16E" xlink:to="loc_us-gaap_LiabilitiesCurrent_D879C7865927B80F92001B3B4068EDD2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_531E117E77381F16AF271B3B406843C9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_531E117E77381F16AF271B3B406843C9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredRentCreditNoncurrent" xlink:label="loc_us-gaap_DeferredRentCreditNoncurrent_ABFBFD053C5196E807E41B3B4068926B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_DeferredRentCreditNoncurrent_ABFBFD053C5196E807E41B3B4068926B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_A39D229E6DDF596152CB1B3B40688951" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_A39D229E6DDF596152CB1B3B40688951" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_F9D00A959906BC163A7A1B3B40681DB2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_Liabilities_F9D00A959906BC163A7A1B3B40681DB2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="loc_us-gaap_CommitmentsAndContingencies_E7FB02EAF23D9EDA76911B3B4069D9D8" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_CommitmentsAndContingencies_E7FB02EAF23D9EDA76911B3B4069D9D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="loc_us-gaap_StockholdersEquityAbstract_F878AB6109E491D066AE1B3B40698F52" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_StockholdersEquityAbstract_F878AB6109E491D066AE1B3B40698F52" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaap_PreferredStockValue_00EE2C3944A15A01EE721B3B406946DC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_F878AB6109E491D066AE1B3B40698F52" xlink:to="loc_us-gaap_PreferredStockValue_00EE2C3944A15A01EE721B3B406946DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_E829A9031F785CBAC05E1B3B4069872D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_F878AB6109E491D066AE1B3B40698F52" xlink:to="loc_us-gaap_CommonStockValue_E829A9031F785CBAC05E1B3B4069872D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_35C5F81E697DF1F6D69B1B3B4069E387" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_F878AB6109E491D066AE1B3B40698F52" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_35C5F81E697DF1F6D69B1B3B4069E387" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_027DF017C620143501F31B3B40693AA3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_F878AB6109E491D066AE1B3B40698F52" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_027DF017C620143501F31B3B40693AA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_543F9F42FB47A26288CD1B3B406A0492" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_F878AB6109E491D066AE1B3B40698F52" xlink:to="loc_us-gaap_StockholdersEquity_543F9F42FB47A26288CD1B3B406A0492" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_85A48CB6025E026553E41B3B406A00A7" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9F147615C6D0BA324B0E1B3B40663F23" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_85A48CB6025E026553E41B3B406A00A7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CondensedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_1A3A08020B500AA0DE781B3B4055C950" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_1A3A08020B500AA0DE781B3B4055C950" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_0478223666E2975440B51B3B4056C3DB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_0478223666E2975440B51B3B4056C3DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesIssued" xlink:label="loc_us-gaap_PreferredStockSharesIssued_D35D38AD0F7C280CCE241B3B40568AA3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_PreferredStockSharesIssued_D35D38AD0F7C280CCE241B3B40568AA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_97F041DEBE40DE41ABF41B3B40566A07" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_97F041DEBE40DE41ABF41B3B40566A07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_2F4927F485FB03CEC7F71B3B4056CE6E" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_2F4927F485FB03CEC7F71B3B4056CE6E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_FE6575D200D5941395531B3B40579050" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_FE6575D200D5941395531B3B40579050" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_30E6BC4BD4269F9644CC1B3B405778A1" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_CommonStockSharesIssued_30E6BC4BD4269F9644CC1B3B405778A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_96B1728E5499C57620701B3B405778A0" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_5A4E2278FC74C304C0CD1B3B4055A6A3" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_96B1728E5499C57620701B3B405778A0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CondensedStatementsOfCashFlows" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_8437C5EC4FECE780B4F01B3B403C5BD5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_8437C5EC4FECE780B4F01B3B403C5BD5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_88E1A129E46DF22ADC8F1B3B403C2875" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_8437C5EC4FECE780B4F01B3B403C5BD5" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_88E1A129E46DF22ADC8F1B3B403C2875" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_8437C5EC4FECE780B4F01B3B403C5BD5" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_BA22717A8C9670BCAE1C1B3B403C2FF3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_BA22717A8C9670BCAE1C1B3B403C2FF3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisposalGroupNotDiscontinuedOperationGainLossOnDisposal" xlink:label="loc_us-gaap_DisposalGroupNotDiscontinuedOperationGainLossOnDisposal_ECC205CA3531B4F934C11B3B403DDF08" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:to="loc_us-gaap_DisposalGroupNotDiscontinuedOperationGainLossOnDisposal_ECC205CA3531B4F934C11B3B403DDF08" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_22FB33200E7995860A341B3B403D25CB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:to="loc_us-gaap_ShareBasedCompensation_22FB33200E7995860A341B3B403D25CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherOperatingActivitiesCashFlowStatement" xlink:label="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_B405AA86B41A414EF12B1B3B403D6F01" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:to="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_B405AA86B41A414EF12B1B3B403D6F01" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_3FF84B613B59B9B3608C1B3B403D37A2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_3FF84B613B59B9B3608C1B3B403D37A2" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_InterestExpenseandPrepaymentPenalty" xlink:label="loc_vcyt_InterestExpenseandPrepaymentPenalty_75C61CB462A4C42D80A41B3B403D8C35" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BC901FA6D951A92BFBF31B3B403CBD87" xlink:to="loc_vcyt_InterestExpenseandPrepaymentPenalty_75C61CB462A4C42D80A41B3B403D8C35" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_8437C5EC4FECE780B4F01B3B403C5BD5" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_6E48AFFCCE80DD78802B1B3B403EB099" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_6E48AFFCCE80DD78802B1B3B403EB099" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_A5EDF03FC794130714121B3B403EEA94" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_A5EDF03FC794130714121B3B403EEA94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_E4504BFD83C7A539AC3E1B3B403E61A2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_E4504BFD83C7A539AC3E1B3B403E61A2" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_IncreaseDecreaseOperatingLeaseRightOfUseAssetLeaseLiability" xlink:label="loc_vcyt_IncreaseDecreaseOperatingLeaseRightOfUseAssetLeaseLiability_F8C7E16C456A788CB2FF1B3B403E01D6" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:to="loc_vcyt_IncreaseDecreaseOperatingLeaseRightOfUseAssetLeaseLiability_F8C7E16C456A788CB2FF1B3B403E01D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_350CC2C40BC31BC154721B3B403F48B6" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_350CC2C40BC31BC154721B3B403F48B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_D5C7B17356A8678ABFA71B3B403F4C08" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_D5C7B17356A8678ABFA71B3B403F4C08" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent" xlink:label="loc_vcyt_IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent_E6D9C831EDDAB063FA961B3B403FECA8" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_09B64E812171E891C2271B3B403E1335" xlink:to="loc_vcyt_IncreaseDecreaseInAccruedLiabilitiesAndDeferredRent_E6D9C831EDDAB063FA961B3B403FECA8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_6D61DB59E85A625BEACF1B3B403F1C70" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_8437C5EC4FECE780B4F01B3B403C5BD5" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_6D61DB59E85A625BEACF1B3B403F1C70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_98352A860C7AE26F03061B3B403F94AC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_98352A860C7AE26F03061B3B403F94AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_9B5580F7C7189CD5B6821B3B403F609E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_98352A860C7AE26F03061B3B403F94AC" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_9B5580F7C7189CD5B6821B3B403F609E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_93E54737D119DD6EF7F41B3B4040802D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_98352A860C7AE26F03061B3B403F94AC" xlink:to="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_93E54737D119DD6EF7F41B3B4040802D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_F5D949E4753A568BF8C61B3B40402DC3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_98352A860C7AE26F03061B3B403F94AC" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_F5D949E4753A568BF8C61B3B40402DC3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_84BF8F82F3C9C2366DFF1B3B4040E033" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_84BF8F82F3C9C2366DFF1B3B4040E033" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_E07524E3F5ACC392F56C1B3B404012DD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_E07524E3F5ACC392F56C1B3B404012DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromLegalSettlements" xlink:label="loc_us-gaap_ProceedsFromLegalSettlements_DAF5F0CD810B4C9E08FF1B3B40412FD9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:to="loc_us-gaap_ProceedsFromLegalSettlements_DAF5F0CD810B4C9E08FF1B3B40412FD9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeasePrincipalPayments" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_0315C126A3D46B5C46AB1B3B4041697F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_0315C126A3D46B5C46AB1B3B4041697F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_095891510062C315CF771B3B404111B3" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_095891510062C315CF771B3B404111B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_901F13D6D0DC1679867E1B3B4041ADF4" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_1841A552F4AEB460F1D61B3B40407E65" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_901F13D6D0DC1679867E1B3B4041ADF4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_6B8D2B7612E110C4DE0E1B3B40416ADE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_6B8D2B7612E110C4DE0E1B3B40416ADE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_CE0CE6178EB6F8DC20C81B3B404199D4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_CE0CE6178EB6F8DC20C81B3B404199D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_93F7921B1687CC4444AC1B3B40428B74" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_93F7921B1687CC4444AC1B3B40428B74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ECC52251175900B339C01B3B403B259C" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_CC80823FE336DE1C424A1B3B4042AF61" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_CC80823FE336DE1C424A1B3B4042AF61" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_CapitalExpendituresIncurredButNotYetPaidNet" xlink:label="loc_vcyt_CapitalExpendituresIncurredButNotYetPaidNet_C3FA842E87616B8D45581B3B4042F554" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:to="loc_vcyt_CapitalExpendituresIncurredButNotYetPaidNet_C3FA842E87616B8D45581B3B4042F554" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InterestPaidNet" xlink:label="loc_us-gaap_InterestPaidNet_28848ECB4A57F07650FF1B3B404212F1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:to="loc_us-gaap_InterestPaidNet_28848ECB4A57F07650FF1B3B404212F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_BA00ADA4E9D389BEC3B11B3B40431EF0" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_BA00ADA4E9D389BEC3B11B3B40431EF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_C841CC2709128EF303F31B3B4043D078" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_C841CC2709128EF303F31B3B4043D078" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5AD8C7553618E3454BE11B3B4043733D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_96AAFE8A050A3D5FA5211B3B40420C32" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5AD8C7553618E3454BE11B3B4043733D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CondensedStatementsOfOperationsAndComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_CDF523AA9E2FA28240491B3B083ED105" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_CDF523AA9E2FA28240491B3B083ED105" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaap_CostOfRevenue_9A0E131552FCC9D8C5241B3B08484FA9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:to="loc_us-gaap_CostOfRevenue_9A0E131552FCC9D8C5241B3B08484FA9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_E22BD9ED2943FE2D9D131B3B0848A5FE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_E22BD9ED2943FE2D9D131B3B0848A5FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SellingAndMarketingExpense" xlink:label="loc_us-gaap_SellingAndMarketingExpense_26699502D9652204A8B31B3B0848B270" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:to="loc_us-gaap_SellingAndMarketingExpense_26699502D9652204A8B31B3B0848B270" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_6DA6F7A6E10055F725E61B3B0849E64A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_6DA6F7A6E10055F725E61B3B0849E64A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_69B89B4B85AACC9BDFB51B3B08499CA3" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_69B89B4B85AACC9BDFB51B3B08499CA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostsAndExpenses" xlink:label="loc_us-gaap_CostsAndExpenses_752A6C8BA1F86C18C7CC1B3B084933A7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_D53DD1F9E9A138381DE91B3B08479AFF" xlink:to="loc_us-gaap_CostsAndExpenses_752A6C8BA1F86C18C7CC1B3B084933A7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_245E8F0D44DBD62334FE1B3B08496785" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_OperatingIncomeLoss_245E8F0D44DBD62334FE1B3B08496785" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_1ACE3ECCF2F15A886C201B3B08498498" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_InterestExpense_1ACE3ECCF2F15A886C201B3B08498498" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_7B9C5BA705E526CD23781B3B084A9BE8" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_7B9C5BA705E526CD23781B3B084A9BE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_5D7D0159F82AA12FFE301B3B084A315C" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_5D7D0159F82AA12FFE301B3B084A315C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_A900E659CECBE49808B01B3B084A8CE1" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_A900E659CECBE49808B01B3B084A8CE1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_37B9FC91E2364EE179871B3B084AFE40" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_37B9FC91E2364EE179871B3B084AFE40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_A54ED6911BFA3A72F8A61B3B084A7463" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_1292B7C461B7DB711F9A1B3B0834CF4B" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_A54ED6911BFA3A72F8A61B3B084A7463" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CondensedStatementsOfStockholdersEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_688BAF8A53A27D9C98C92EE40F1399AD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_7A187464FAC9D74EC0DA2EE40F13D194" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_688BAF8A53A27D9C98C92EE40F1399AD" xlink:to="loc_us-gaap_StatementTable_7A187464FAC9D74EC0DA2EE40F13D194" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_7CB04F3E66D6524ED1BC2EE40F1323D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_7A187464FAC9D74EC0DA2EE40F13D194" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_7CB04F3E66D6524ED1BC2EE40F1323D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_26B1F49E13B215FBA4472EE40F130CAB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_7CB04F3E66D6524ED1BC2EE40F1323D6" xlink:to="loc_us-gaap_EquityComponentDomain_26B1F49E13B215FBA4472EE40F130CAB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_32AF6706AD326DFCE15C2EE40F1355C8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_26B1F49E13B215FBA4472EE40F130CAB" xlink:to="loc_us-gaap_CommonStockMember_32AF6706AD326DFCE15C2EE40F1355C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_A0DE871DA299C267B85F2EE40F13FF77" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_26B1F49E13B215FBA4472EE40F130CAB" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_A0DE871DA299C267B85F2EE40F13FF77" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_75147CF5E1F4160DFD9A2EE40F137D95" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_26B1F49E13B215FBA4472EE40F130CAB" xlink:to="loc_us-gaap_RetainedEarningsMember_75147CF5E1F4160DFD9A2EE40F137D95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_93E709915E6A94B11F7D2EE40F131157" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_7A187464FAC9D74EC0DA2EE40F13D194" xlink:to="loc_us-gaap_StatementLineItems_93E709915E6A94B11F7D2EE40F131157" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_93E709915E6A94B11F7D2EE40F131157" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_8EDE2B96C953181D0A372EE40F17B59F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_StockholdersEquity_8EDE2B96C953181D0A372EE40F17B59F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharesOutstanding" xlink:label="loc_us-gaap_SharesOutstanding_7561E4EF4E812C5B12692EE40F17E36D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_SharesOutstanding_7561E4EF4E812C5B12692EE40F17E36D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_D7FD93A66F621621147C2EE40F17E7DB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_D7FD93A66F621621147C2EE40F17E7DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_AFFFE9AACD58570440482EE40F173978" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_AFFFE9AACD58570440482EE40F173978" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardValueOptionsandNonOptionEquityInstrumentsExercisesinPeriod" xlink:label="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardValueOptionsandNonOptionEquityInstrumentsExercisesinPeriod_79E7803013FBB70CA02E2EE40F17B047" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardValueOptionsandNonOptionEquityInstrumentsExercisesinPeriod_79E7803013FBB70CA02E2EE40F17B047" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsandNonOptionEquityInstrumentsExercisesinPeriod" xlink:label="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsandNonOptionEquityInstrumentsExercisesinPeriod_67C000858E56A56CD0562EE40F175CEA" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_vcyt_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsandNonOptionEquityInstrumentsExercisesinPeriod_67C000858E56A56CD0562EE40F175CEA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_75F76E1E932D4A1C12032EE40F179DAB" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_75F76E1E932D4A1C12032EE40F179DAB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_39E5ED630DCB02FE85012EE40F17223F" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_39E5ED630DCB02FE85012EE40F17223F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet" xlink:label="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_27F318CAB574AB94158A2EE40F17FEFF" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet_27F318CAB574AB94158A2EE40F17FEFF" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployee" xlink:label="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployee_0A27ABFFC9C18D40330D2EE40F17C233" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployee_0A27ABFFC9C18D40330D2EE40F17C233" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationNonEmployee" xlink:label="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationNonEmployee_5F0E61A68AE7AD6528FB2EE40F1762E9" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationNonEmployee_5F0E61A68AE7AD6528FB2EE40F1762E9" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationESPP" xlink:label="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationESPP_D59D50F0F8D39DF99F462EE40F1E5768" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_vcyt_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationESPP_D59D50F0F8D39DF99F462EE40F1E5768" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_LegalSettlementRegardingShortSwingProfitsNetOfTax" xlink:label="loc_vcyt_LegalSettlementRegardingShortSwingProfitsNetOfTax_D736E18F7A04AC6744332EF5977FB47F" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_vcyt_LegalSettlementRegardingShortSwingProfitsNetOfTax_D736E18F7A04AC6744332EF5977FB47F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_943166EF6B2A98AB95C02EE40F1FB07A" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_943166EF6B2A98AB95C02EE40F1FB07A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_E56E12EAE804EE9022512EE40F1FAEFD" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_E56E12EAE804EE9022512EE40F1FAEFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_74689628D8F81492F2732EE40F1F70BD" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_StockholdersEquity_74689628D8F81492F2732EE40F1F70BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharesOutstanding" xlink:label="loc_us-gaap_SharesOutstanding_45B00FCC22A555187FC12EE40F1F19F6" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_A396A7CF66DF1E5BB9212EE40F172690" xlink:to="loc_us-gaap_SharesOutstanding_45B00FCC22A555187FC12EE40F1F19F6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/CondensedStatementsOfStockholdersEquityParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_AFD98BD7838835DD15313F65D9B68148" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_5E9ED1D8101E307E9D753F65D9B640DC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_AFD98BD7838835DD15313F65D9B68148" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_5E9ED1D8101E307E9D753F65D9B640DC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/Debt" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_49B0534DCF73252D80A51B3B3F587049" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_84E9D3CAE20D83EF764E1B3B3F58DABF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_49B0534DCF73252D80A51B3B3F587049" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_84E9D3CAE20D83EF764E1B3B3F58DABF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtDebtObligationForBorrowingsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_0B792EBE4DEB218842341B3B3F15F1F3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_7D33218185B9CE86885A1B3B3F1544DE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_0B792EBE4DEB218842341B3B3F15F1F3" xlink:to="loc_us-gaap_DebtInstrumentTable_7D33218185B9CE86885A1B3B3F1544DE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_F6FC3026295C4F924F071B3B3F166A17" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7D33218185B9CE86885A1B3B3F1544DE" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_F6FC3026295C4F924F071B3B3F166A17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_11E3B416EE8B640C7A9F1B3B3F16BC30" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_F6FC3026295C4F924F071B3B3F166A17" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_11E3B416EE8B640C7A9F1B3B3F16BC30" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="loc_us-gaap_LineOfCreditMember_1E03D33EB81F2CB7A31B1B3B3F1644B7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_11E3B416EE8B640C7A9F1B3B3F16BC30" xlink:to="loc_us-gaap_LineOfCreditMember_1E03D33EB81F2CB7A31B1B3B3F1644B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_A1C484F8B891F3DFF0561B3B3F16AFAE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_7D33218185B9CE86885A1B3B3F1544DE" xlink:to="loc_us-gaap_DebtInstrumentLineItems_A1C484F8B891F3DFF0561B3B3F16AFAE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_C66339E1519D8E2B00131B3B3F17C822" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_A1C484F8B891F3DFF0561B3B3F16AFAE" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_C66339E1519D8E2B00131B3B3F17C822" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DebtInstrumentEndOfTermInterestObligationAmount" xlink:label="loc_vcyt_DebtInstrumentEndOfTermInterestObligationAmount_7027E05FEF39A030EC9E1B3B3F176232" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_A1C484F8B891F3DFF0561B3B3F16AFAE" xlink:to="loc_vcyt_DebtInstrumentEndOfTermInterestObligationAmount_7027E05FEF39A030EC9E1B3B3F176232" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscount" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_A7E433EB7349960548B21B3B3F1C9E1B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_A1C484F8B891F3DFF0561B3B3F16AFAE" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_A7E433EB7349960548B21B3B3F1C9E1B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermDebt" xlink:label="loc_us-gaap_LongTermDebt_EB158D79B192792327B21B3B3F1C0233" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" priority="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_A1C484F8B891F3DFF0561B3B3F16AFAE" xlink:to="loc_us-gaap_LongTermDebt_EB158D79B192792327B21B3B3F1C0233" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_DD62857308F6808ACB521B3B3F3A93EC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_DD62857308F6808ACB521B3B3F3A93EC" xlink:to="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DebtPrepaymentTrancheAxis" xlink:label="loc_vcyt_DebtPrepaymentTrancheAxis_21461A2D80B2CA84840E1B3B3F3A1E23" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:to="loc_vcyt_DebtPrepaymentTrancheAxis_21461A2D80B2CA84840E1B3B3F3A1E23" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DebtPaymentTrancheDomain" xlink:label="loc_vcyt_DebtPaymentTrancheDomain_4ED0AA0ADADB3D3025741B3B3F3B48A1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPrepaymentTrancheAxis_21461A2D80B2CA84840E1B3B3F3A1E23" xlink:to="loc_vcyt_DebtPaymentTrancheDomain_4ED0AA0ADADB3D3025741B3B3F3B48A1" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DebtPrepaymentTrancheOneMember" xlink:label="loc_vcyt_DebtPrepaymentTrancheOneMember_66D8A8637EF172B0492F1B3B3F3B3461" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPaymentTrancheDomain_4ED0AA0ADADB3D3025741B3B3F3B48A1" xlink:to="loc_vcyt_DebtPrepaymentTrancheOneMember_66D8A8637EF172B0492F1B3B3F3B3461" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DebtPrepaymentTrancheTwoMember" xlink:label="loc_vcyt_DebtPrepaymentTrancheTwoMember_624145B86374D85D74951B3B3F3BDCD6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPaymentTrancheDomain_4ED0AA0ADADB3D3025741B3B3F3B48A1" xlink:to="loc_vcyt_DebtPrepaymentTrancheTwoMember_624145B86374D85D74951B3B3F3BDCD6" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DebtPrepaymentTrancheThreeMember" xlink:label="loc_vcyt_DebtPrepaymentTrancheThreeMember_5E9AFE512E22B1EA27D81B3B3F3B6642" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DebtPaymentTrancheDomain_4ED0AA0ADADB3D3025741B3B3F3B48A1" xlink:to="loc_vcyt_DebtPrepaymentTrancheThreeMember_5E9AFE512E22B1EA27D81B3B3F3B6642" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_1C774671F12D2841BD241B3B3F3B579E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:to="loc_us-gaap_CreditFacilityAxis_1C774671F12D2841BD241B3B3F3B579E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_464BA007E62C97F7FCB41B3B3F3CF77D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_1C774671F12D2841BD241B3B3F3B579E" xlink:to="loc_us-gaap_CreditFacilityDomain_464BA007E62C97F7FCB41B3B3F3CF77D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SecuredDebtMember" xlink:label="loc_us-gaap_SecuredDebtMember_95BD8AAB0D3B29781E321B3B3F3C719F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_464BA007E62C97F7FCB41B3B3F3CF77D" xlink:to="loc_us-gaap_SecuredDebtMember_95BD8AAB0D3B29781E321B3B3F3C719F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_2F5FA4CCA97744501E241B3B3F3CBDE2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_464BA007E62C97F7FCB41B3B3F3CF77D" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_2F5FA4CCA97744501E241B3B3F3CBDE2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_7BFE49915A627224DFD41B3B3F3CBCEB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_7BFE49915A627224DFD41B3B3F3CBCEB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_FA76110FEC69072F5D481B3B3F3DA96F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_7BFE49915A627224DFD41B3B3F3CBCEB" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_FA76110FEC69072F5D481B3B3F3DA96F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_SiliconValleyBankMember" xlink:label="loc_vcyt_SiliconValleyBankMember_F6F0687A414F75B236C41B3B3F3D702C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_FA76110FEC69072F5D481B3B3F3DA96F" xlink:to="loc_vcyt_SiliconValleyBankMember_F6F0687A414F75B236C41B3B3F3D702C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_A99B672B3CAD184D8E481B3B3F3D9DCE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_A99B672B3CAD184D8E481B3B3F3D9DCE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_9FFE9B567A3DD2DBE92F1B3B3F3DDA5D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_A99B672B3CAD184D8E481B3B3F3D9DCE" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_9FFE9B567A3DD2DBE92F1B3B3F3DDA5D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="loc_us-gaap_LineOfCreditMember_789F03B86B432692CCCA1B3B3F3E9EBE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_9FFE9B567A3DD2DBE92F1B3B3F3DDA5D" xlink:to="loc_us-gaap_LineOfCreditMember_789F03B86B432692CCCA1B3B3F3E9EBE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="loc_us-gaap_VariableRateAxis_DA957E24E828C83C2EE81B3B3F3E8500" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:to="loc_us-gaap_VariableRateAxis_DA957E24E828C83C2EE81B3B3F3E8500" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_975A374DA2BFDE2229971B3B3F3EA3A1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_DA957E24E828C83C2EE81B3B3F3E8500" xlink:to="loc_us-gaap_VariableRateDomain_975A374DA2BFDE2229971B3B3F3EA3A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_B3F1677F258B63E566001B3B3F3E2F07" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_975A374DA2BFDE2229971B3B3F3EA3A1" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_B3F1677F258B63E566001B3B3F3E2F07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_4E79E0F4785532E745931B3B3F3FC2E7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:to="loc_srt_RangeAxis_4E79E0F4785532E745931B3B3F3FC2E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_1B30727F975F177B1D681B3B3F3FA747" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_4E79E0F4785532E745931B3B3F3FC2E7" xlink:to="loc_srt_RangeMember_1B30727F975F177B1D681B3B3F3FA747" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_21284D8F4F1228F36BBF1B3B3F3FF613" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_1B30727F975F177B1D681B3B3F3FA747" xlink:to="loc_srt_MinimumMember_21284D8F4F1228F36BBF1B3B3F3FF613" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_C2AFE985D2314128CD421B3B3F3AA530" xlink:to="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_EE604B6C265A34A466171B3B3F4058FD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_EE604B6C265A34A466171B3B3F4058FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_50D71A7A40C5960C11651B3B3F402023" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_50D71A7A40C5960C11651B3B3F402023" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_C7CB7247B19DF10279B21B3B3F407FAA" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_C7CB7247B19DF10279B21B3B3F407FAA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_980A61F366BB9582D6BD1B3B3F402033" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_980A61F366BB9582D6BD1B3B3F402033" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DebtInstrumentPrepaymentPremium" xlink:label="loc_vcyt_DebtInstrumentPrepaymentPremium_045FD7BA5E4C0B4A6CF61B3B3F45B985" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_vcyt_DebtInstrumentPrepaymentPremium_045FD7BA5E4C0B4A6CF61B3B3F45B985" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_2E319ADFD26FE8EDBA301B3B3F46DDEF" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_2E319ADFD26FE8EDBA301B3B3F46DDEF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentPeriodicPaymentTermsBalloonPaymentToBePaid" xlink:label="loc_us-gaap_DebtInstrumentPeriodicPaymentTermsBalloonPaymentToBePaid_0DCA40FD4071BD4680281B3B3F460B5A" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_us-gaap_DebtInstrumentPeriodicPaymentTermsBalloonPaymentToBePaid_0DCA40FD4071BD4680281B3B3F460B5A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_LiquidityRequirementMinimum" xlink:label="loc_vcyt_LiquidityRequirementMinimum_05BC7D269CB21D7D98CB1B3B3F46F480" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_vcyt_LiquidityRequirementMinimum_05BC7D269CB21D7D98CB1B3B3F46F480" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_C356783199163AF9941F1B3B3F4692FC" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_4EDFBD22EEB5D5E54A581B3B3F404594" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_C356783199163AF9941F1B3B3F4692FC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DebtTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_4E39A2581C060F4EEB861B3B3F50EA26" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfDebtTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfDebtTableTextBlock_E3F923BBB4C0C2D432F11B3B3F501E77" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_4E39A2581C060F4EEB861B3B3F50EA26" xlink:to="loc_us-gaap_ScheduleOfDebtTableTextBlock_E3F923BBB4C0C2D432F11B3B3F501E77" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/DocumentAndEntityInformation" xlink:type="extended">
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DocumentAndEntityInformationAbstract" xlink:label="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:type="locator" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_5658C1F7FF4A4C82DC661B3B40721239" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntityRegistrantName_5658C1F7FF4A4C82DC661B3B40721239" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_79C8CEC1549DBB9E84791B3B40720CA8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntityCentralIndexKey_79C8CEC1549DBB9E84791B3B40720CA8" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_6B3E6948F2E9A6F540461B3B4072A2C4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_DocumentType_6B3E6948F2E9A6F540461B3B4072A2C4" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_208849F9F59149FF65521B3B40720FF1" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_DocumentPeriodEndDate_208849F9F59149FF65521B3B40720FF1" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_ECF6A14BCD37CEAE32D81B3B4072CCA9" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_AmendmentFlag_ECF6A14BCD37CEAE32D81B3B4072CCA9" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_dei_CurrentFiscalYearEndDate_FA3D25E78F288D0297E31B3B40734CD3" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_CurrentFiscalYearEndDate_FA3D25E78F288D0297E31B3B40734CD3" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_dei_EntityCurrentReportingStatus_28E6DCB6F611EBB115A81B3B40732804" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntityCurrentReportingStatus_28E6DCB6F611EBB115A81B3B40732804" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityFilerCategory" xlink:label="loc_dei_EntityFilerCategory_5C8AAAD972EE0F43C7D01B3B4073445C" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntityFilerCategory_5C8AAAD972EE0F43C7D01B3B4073445C" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_dei_EntityEmergingGrowthCompany_84B9EAF130AFE42983051B3B4073FE9F" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntityEmergingGrowthCompany_84B9EAF130AFE42983051B3B4073FE9F" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntitySmallBusiness" xlink:label="loc_dei_EntitySmallBusiness_41DE501511EE8CA3C1E71B3B40732B70" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntitySmallBusiness_41DE501511EE8CA3C1E71B3B40732B70" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityShellCompany" xlink:label="loc_dei_EntityShellCompany_D90447FA13E164D3DB841B3B4073E70C" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntityShellCompany_D90447FA13E164D3DB841B3B4073E70C" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_AF74A0434008558243F81B3B407369C0" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_AF74A0434008558243F81B3B407369C0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_dei_DocumentFiscalYearFocus_9B2DAEC36F80F1C564181B3B407471C0" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_DocumentFiscalYearFocus_9B2DAEC36F80F1C564181B3B407471C0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_dei_DocumentFiscalPeriodFocus_5EA2AA8F9ABA122E19871B3B407499F0" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_DocumentAndEntityInformationAbstract_C356325AC65C5135A9011B3B4071193B" xlink:to="loc_dei_DocumentFiscalPeriodFocus_5EA2AA8F9ABA122E19871B3B407499F0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_E1FA1162DB09D0763F3B1B3B3FB15E0F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_697593990F91306085521B3B3FB1310C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_E1FA1162DB09D0763F3B1B3B3FB15E0F" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_697593990F91306085521B3B3FB1310C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/FairValueMeasurementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_B7F7EFA06C7C9176110B1B3B3FA0BC41" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_FCE5D7E496EB9CD178191B3B3FA5A00E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_B7F7EFA06C7C9176110B1B3B3FA0BC41" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_FCE5D7E496EB9CD178191B3B3FA5A00E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_9A54F1A6D9A4164BF6531B3B3FA571E2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_FCE5D7E496EB9CD178191B3B3FA5A00E" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_9A54F1A6D9A4164BF6531B3B3FA571E2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_D30B2C877C0E42520E651B3B3FA6B065" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_9A54F1A6D9A4164BF6531B3B3FA571E2" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_D30B2C877C0E42520E651B3B3FA6B065" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_FD8A2AE4B161926BB3D81B3B3FA6B4D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_D30B2C877C0E42520E651B3B3FA6B065" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_FD8A2AE4B161926BB3D81B3B3FA6B4D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueByAssetClassAxis" xlink:label="loc_us-gaap_FairValueByAssetClassAxis_A7D37D602CDB11A664341B3B3FA6A1E7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_FCE5D7E496EB9CD178191B3B3FA5A00E" xlink:to="loc_us-gaap_FairValueByAssetClassAxis_A7D37D602CDB11A664341B3B3FA6A1E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_00D57E94874714DEFF571B3B3FA7D77E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByAssetClassAxis_A7D37D602CDB11A664341B3B3FA6A1E7" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_00D57E94874714DEFF571B3B3FA7D77E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MoneyMarketFundsMember" xlink:label="loc_us-gaap_MoneyMarketFundsMember_8E90882515D544D2E49F1B3B3FA75376" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisUnobservableInputReconciliationByAssetClassDomain_00D57E94874714DEFF571B3B3FA7D77E" xlink:to="loc_us-gaap_MoneyMarketFundsMember_8E90882515D544D2E49F1B3B3FA75376" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseArrangementTypeAxis" xlink:label="loc_us-gaap_LeaseArrangementTypeAxis_140EFACD91D654C32CF41B3B3FA75CDE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_FCE5D7E496EB9CD178191B3B3FA5A00E" xlink:to="loc_us-gaap_LeaseArrangementTypeAxis_140EFACD91D654C32CF41B3B3FA75CDE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseArrangementTypeDomain" xlink:label="loc_us-gaap_LeaseArrangementTypeDomain_51F8D76F2078116699ED1B3B3FA7E7CA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeAxis_140EFACD91D654C32CF41B3B3FA75CDE" xlink:to="loc_us-gaap_LeaseArrangementTypeDomain_51F8D76F2078116699ED1B3B3FA7E7CA" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember" xlink:label="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_DB3AB037464A898EC1061B3B3FA8B551" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeDomain_51F8D76F2078116699ED1B3B3FA7E7CA" xlink:to="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_DB3AB037464A898EC1061B3B3FA8B551" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_92FF72793DCABB2618701B3B3FA8FB1A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_FCE5D7E496EB9CD178191B3B3FA5A00E" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_92FF72793DCABB2618701B3B3FA8FB1A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_136AEDF9FC555069E7151B3B3FA8B7A3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_92FF72793DCABB2618701B3B3FA8FB1A" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_136AEDF9FC555069E7151B3B3FA8B7A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_FFF42696B5E0273B35AF1B3B3FA91B68" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_92FF72793DCABB2618701B3B3FA8FB1A" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_FFF42696B5E0273B35AF1B3B3FA91B68" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_3AC8B815A0F5E1E1609A1B3B3ED51667" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_BA41F0C79CE31A263ED71B3B3ED53C76" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_3AC8B815A0F5E1E1609A1B3B3ED51667" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_BA41F0C79CE31A263ED71B3B3ED53C76" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/IncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_8ACC13584D21F8C8D0DC1B3B3EC76E92" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UnrecognizedTaxBenefits" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_345C933E26B47E65A40A1B3B3EC80FDA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8ACC13584D21F8C8D0DC1B3B3EC76E92" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_345C933E26B47E65A40A1B3B3EC80FDA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_8AD811A38AC13BD84CFD1B3B3ECDE049" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_8ACC13584D21F8C8D0DC1B3B3EC76E92" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_8AD811A38AC13BD84CFD1B3B3ECDE049" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/NetLossPerCommonShare" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_F495947E641C2B9423501B3B3FE9687B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_734F85CB0F392846D9E11B3B3FEA8F35" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_F495947E641C2B9423501B3B3FE9687B" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_734F85CB0F392846D9E11B3B3FEA8F35" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/NetLossPerCommonShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_526FA69F7C95FFA7BCE81B3B3FD8A3D3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_75A57201AED3261F481C1B3B3FD8DCA9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_526FA69F7C95FFA7BCE81B3B3FD8A3D3" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_75A57201AED3261F481C1B3B3FD8DCA9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_9F88D097EEABDC8C82E61B3B3FD81400" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_75A57201AED3261F481C1B3B3FD8DCA9" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_9F88D097EEABDC8C82E61B3B3FD81400" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8053E1A05B6F8303C46D1B3B3FD904E6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_9F88D097EEABDC8C82E61B3B3FD81400" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8053E1A05B6F8303C46D1B3B3FD904E6" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_EmployeeAndNonEmployeeStockOptionMember" xlink:label="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_FDC327F16FBA891F6B851B3B3FD90E78" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8053E1A05B6F8303C46D1B3B3FD904E6" xlink:to="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_FDC327F16FBA891F6B851B3B3FD90E78" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeStockOptionMember" xlink:label="loc_us-gaap_EmployeeStockOptionMember_4157BBE5573AAB3836A71B3B3FD9A5DB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8053E1A05B6F8303C46D1B3B3FD904E6" xlink:to="loc_us-gaap_EmployeeStockOptionMember_4157BBE5573AAB3836A71B3B3FD9A5DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_BFFB02115867A2FD40F91B3B3FD910D0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8053E1A05B6F8303C46D1B3B3FD904E6" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_BFFB02115867A2FD40F91B3B3FD910D0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_515DAAFAF06B3E8BF52B1B3B3FDA05A4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_75A57201AED3261F481C1B3B3FD8DCA9" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_515DAAFAF06B3E8BF52B1B3B3FDA05A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_DB36279E908BC5029BDD1B3B3FDA802A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_515DAAFAF06B3E8BF52B1B3B3FDA05A4" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_DB36279E908BC5029BDD1B3B3FDA802A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/NetLossPerCommonShareTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_FFFC3ACD679C36F871961B3B3FE269ED" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_3C76642BBAB6B51B7B391B3B3FE251E1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_FFFC3ACD679C36F871961B3B3FE269ED" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_3C76642BBAB6B51B7B391B3B3FE251E1" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusiness" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_3408342931528DC57BAE1B3B4030201E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock" xlink:label="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_30C993CF31411E9764A61B3B4030C1CA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3408342931528DC57BAE1B3B4030201E" xlink:to="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_30C993CF31411E9764A61B3B4030C1CA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessCreditRiskDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_674CA3B585487B5FE1C21B3B3FFE63BC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskTable" xlink:label="loc_us-gaap_ConcentrationRiskTable_66A058D9A0DD3A8F280A1B3B3FFEB81B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_674CA3B585487B5FE1C21B3B3FFE63BC" xlink:to="loc_us-gaap_ConcentrationRiskTable_66A058D9A0DD3A8F280A1B3B3FFEB81B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_1B3D29190BE041F509E51B3B3FFF375F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_66A058D9A0DD3A8F280A1B3B3FFEB81B" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_1B3D29190BE041F509E51B3B3FFF375F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_FC0A120DD3C0CE52CD9B1B3B3FFF28A4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_1B3D29190BE041F509E51B3B3FFF375F" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_FC0A120DD3C0CE52CD9B1B3B3FFF28A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SalesRevenueNetMember" xlink:label="loc_us-gaap_SalesRevenueNetMember_2C5A508EC5133146AB531B3B3FFFC6CB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_FC0A120DD3C0CE52CD9B1B3B3FFF28A4" xlink:to="loc_us-gaap_SalesRevenueNetMember_2C5A508EC5133146AB531B3B3FFFC6CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableMember" xlink:label="loc_us-gaap_AccountsReceivableMember_75848821610E2208F7911B3B4000768C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_FC0A120DD3C0CE52CD9B1B3B3FFF28A4" xlink:to="loc_us-gaap_AccountsReceivableMember_75848821610E2208F7911B3B4000768C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_300259C930908EB39A631B3B4000E583" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_66A058D9A0DD3A8F280A1B3B3FFEB81B" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_300259C930908EB39A631B3B4000E583" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_BBA8D893246DE12D8A231B3B40006117" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_300259C930908EB39A631B3B4000E583" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_BBA8D893246DE12D8A231B3B40006117" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CustomerConcentrationRiskMember" xlink:label="loc_us-gaap_CustomerConcentrationRiskMember_11C4060E43D87AB264781B3B4000DDAA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_BBA8D893246DE12D8A231B3B40006117" xlink:to="loc_us-gaap_CustomerConcentrationRiskMember_11C4060E43D87AB264781B3B4000DDAA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CreditConcentrationRiskMember" xlink:label="loc_us-gaap_CreditConcentrationRiskMember_7654E0CF311914F021101B3B4001504A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_BBA8D893246DE12D8A231B3B40006117" xlink:to="loc_us-gaap_CreditConcentrationRiskMember_7654E0CF311914F021101B3B4001504A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MajorCustomersAxis" xlink:label="loc_srt_MajorCustomersAxis_CDD9945FDEDC14EC25C61B3B4001ED7C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_66A058D9A0DD3A8F280A1B3B3FFEB81B" xlink:to="loc_srt_MajorCustomersAxis_CDD9945FDEDC14EC25C61B3B4001ED7C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_NameOfMajorCustomerDomain" xlink:label="loc_srt_NameOfMajorCustomerDomain_EA1529A9D9AE6CAD4C571B3B40013E0A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_CDD9945FDEDC14EC25C61B3B4001ED7C" xlink:to="loc_srt_NameOfMajorCustomerDomain_EA1529A9D9AE6CAD4C571B3B40013E0A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_MedicareMember" xlink:label="loc_vcyt_MedicareMember_A6F8D9BCF7BC85C9C4DC1B3B40019356" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_EA1529A9D9AE6CAD4C571B3B40013E0A" xlink:to="loc_vcyt_MedicareMember_A6F8D9BCF7BC85C9C4DC1B3B40019356" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_UnitedHealthcareMember" xlink:label="loc_vcyt_UnitedHealthcareMember_2E24B716937D25B74E661B3B4002897F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_EA1529A9D9AE6CAD4C571B3B40013E0A" xlink:to="loc_vcyt_UnitedHealthcareMember_2E24B716937D25B74E661B3B4002897F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskLineItems" xlink:label="loc_us-gaap_ConcentrationRiskLineItems_78BEFFF067EA01D1BFE31B3B40025466" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTable_66A058D9A0DD3A8F280A1B3B3FFEB81B" xlink:to="loc_us-gaap_ConcentrationRiskLineItems_78BEFFF067EA01D1BFE31B3B40025466" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_AFC8D3CD56F0019E82081B3B40028853" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_78BEFFF067EA01D1BFE31B3B40025466" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_AFC8D3CD56F0019E82081B3B40028853" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_5A79021F7B706BD5F6823F65D97AA1F7" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTable" xlink:label="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_5A79021F7B706BD5F6823F65D97AA1F7" xlink:to="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_0A0C010226C207FFB19B3F65D97B81AA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_0A0C010226C207FFB19B3F65D97B81AA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_6BF8142BD784F8C8C7123F65D97BD895" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_0A0C010226C207FFB19B3F65D97B81AA" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_6BF8142BD784F8C8C7123F65D97BD895" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableMember" xlink:label="loc_us-gaap_AccountsReceivableMember_D089B20BB915BCD412E33F65D97CC17B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_6BF8142BD784F8C8C7123F65D97BD895" xlink:to="loc_us-gaap_AccountsReceivableMember_D089B20BB915BCD412E33F65D97CC17B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MajorCustomersAxis" xlink:label="loc_srt_MajorCustomersAxis_694DD579DB869F3ABE383F65D97C841D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_srt_MajorCustomersAxis_694DD579DB869F3ABE383F65D97C841D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_NameOfMajorCustomerDomain" xlink:label="loc_srt_NameOfMajorCustomerDomain_357B8530F1D254D869AF3F65D97C4EB4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_MajorCustomersAxis_694DD579DB869F3ABE383F65D97C841D" xlink:to="loc_srt_NameOfMajorCustomerDomain_357B8530F1D254D869AF3F65D97C4EB4" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_JohnsonJohnsonServicesInc.Member" xlink:label="loc_vcyt_JohnsonJohnsonServicesInc.Member_BF3BB8A1F6C5EE6B37E03F65D97C37FA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_357B8530F1D254D869AF3F65D97C4EB4" xlink:to="loc_vcyt_JohnsonJohnsonServicesInc.Member_BF3BB8A1F6C5EE6B37E03F65D97C37FA" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_Perceptav.2Member" xlink:label="loc_vcyt_Perceptav.2Member_17561874F8C9B1E404CB3F65D97D87EF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_NameOfMajorCustomerDomain_357B8530F1D254D869AF3F65D97C4EB4" xlink:to="loc_vcyt_Perceptav.2Member_17561874F8C9B1E404CB3F65D97D87EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_B6583F9636F7449EDA4B3F65D97DB99B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_B6583F9636F7449EDA4B3F65D97DB99B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_1CE87A7B2401CBDF03FD3F65D97D64DD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_B6583F9636F7449EDA4B3F65D97DB99B" xlink:to="loc_us-gaap_TypeOfAdoptionMember_1CE87A7B2401CBDF03FD3F65D97D64DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingStandardsUpdate201409Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201409Member_D6324366CCCD0D274B773F65D97D5355" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_1CE87A7B2401CBDF03FD3F65D97D64DD" xlink:to="loc_us-gaap_AccountingStandardsUpdate201409Member_D6324366CCCD0D274B773F65D97D5355" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingStandardsUpdate201602Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201602Member_01ED146B819657AF1F483F65D97E8C0A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_1CE87A7B2401CBDF03FD3F65D97D64DD" xlink:to="loc_us-gaap_AccountingStandardsUpdate201602Member_01ED146B819657AF1F483F65D97E8C0A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_19966CB15061394AAE8E3F65D97EC60B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_srt_CounterpartyNameAxis_19966CB15061394AAE8E3F65D97EC60B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_5746A48E8F2D006BF6323F65D97E16EE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_19966CB15061394AAE8E3F65D97EC60B" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_5746A48E8F2D006BF6323F65D97E16EE" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_BiopharmaceuticalCompanyMember" xlink:label="loc_vcyt_BiopharmaceuticalCompanyMember_DCE2102FB2DC4F5BC00F3F65D97E4A2B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_5746A48E8F2D006BF6323F65D97E16EE" xlink:to="loc_vcyt_BiopharmaceuticalCompanyMember_DCE2102FB2DC4F5BC00F3F65D97E4A2B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_9E339B98C5368503E0B93F65D97F4E52" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_9E339B98C5368503E0B93F65D97F4E52" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_DC80851DEF497CEB5FCC3F65D97FE0EC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_9E339B98C5368503E0B93F65D97F4E52" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_DC80851DEF497CEB5FCC3F65D97FE0EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OverAllotmentOptionMember" xlink:label="loc_us-gaap_OverAllotmentOptionMember_2E2C9B2890EE60027ECC3F65D97F0CA2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_DC80851DEF497CEB5FCC3F65D97FE0EC" xlink:to="loc_us-gaap_OverAllotmentOptionMember_2E2C9B2890EE60027ECC3F65D97F0CA2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_183C50454670BF65AFDA3F65D980614E" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_srt_ProductOrServiceAxis_183C50454670BF65AFDA3F65D980614E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_DB99AD608F056CAB645A3F65D980110A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_183C50454670BF65AFDA3F65D980614E" xlink:to="loc_srt_ProductsAndServicesDomain_DB99AD608F056CAB645A3F65D980110A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ProvisionofDataandFulfillmentofMilestonesMember" xlink:label="loc_vcyt_ProvisionofDataandFulfillmentofMilestonesMember_F9842B8BD7D587EB0E373F65D980F31E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_DB99AD608F056CAB645A3F65D980110A" xlink:to="loc_vcyt_ProvisionofDataandFulfillmentofMilestonesMember_F9842B8BD7D587EB0E373F65D980F31E" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ProvisionofDataMember" xlink:label="loc_vcyt_ProvisionofDataMember_F8100C6EACFFE1DF44BE3F65D980C87F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_DB99AD608F056CAB645A3F65D980110A" xlink:to="loc_vcyt_ProvisionofDataMember_F8100C6EACFFE1DF44BE3F65D980C87F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DiagnosticServicesMember" xlink:label="loc_vcyt_DiagnosticServicesMember_CC02A6464C897265A04F3F65D980A901" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_DB99AD608F056CAB645A3F65D980110A" xlink:to="loc_vcyt_DiagnosticServicesMember_CC02A6464C897265A04F3F65D980A901" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProductMember" xlink:label="loc_us-gaap_ProductMember_336EDAB7122F4F7F7F5A3F65D9810AA3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_DB99AD608F056CAB645A3F65D980110A" xlink:to="loc_us-gaap_ProductMember_336EDAB7122F4F7F7F5A3F65D9810AA3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ServiceMember" xlink:label="loc_us-gaap_ServiceMember_AF79FDE8F8ED4BA581463F65D981A1A0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_DB99AD608F056CAB645A3F65D980110A" xlink:to="loc_us-gaap_ServiceMember_AF79FDE8F8ED4BA581463F65D981A1A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseArrangementTypeAxis" xlink:label="loc_us-gaap_LeaseArrangementTypeAxis_7BBF1990DDBA0937B5283F65D981477E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_us-gaap_LeaseArrangementTypeAxis_7BBF1990DDBA0937B5283F65D981477E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseArrangementTypeDomain" xlink:label="loc_us-gaap_LeaseArrangementTypeDomain_5A0232BFE7DB43297F5F3F65D98162B4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeAxis_7BBF1990DDBA0937B5283F65D981477E" xlink:to="loc_us-gaap_LeaseArrangementTypeDomain_5A0232BFE7DB43297F5F3F65D98162B4" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember" xlink:label="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_8168153876A8C6162F113F65D98160CD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseArrangementTypeDomain_5A0232BFE7DB43297F5F3F65D98162B4" xlink:to="loc_vcyt_HeadquartersAndLaboratoryFacilitiesSouthSanFranciscoLeaseTwoMember_8168153876A8C6162F113F65D98160CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis" xlink:label="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_33AA6EAFEBFBE17DEC7F3F65D982AA94" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_33AA6EAFEBFBE17DEC7F3F65D982AA94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ReceivableTypeDomain" xlink:label="loc_us-gaap_ReceivableTypeDomain_3AFF8F71BBD60FD5C0FC3F65D9828AF1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_33AA6EAFEBFBE17DEC7F3F65D982AA94" xlink:to="loc_us-gaap_ReceivableTypeDomain_3AFF8F71BBD60FD5C0FC3F65D9828AF1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccruedIncomeReceivableMember" xlink:label="loc_us-gaap_AccruedIncomeReceivableMember_2B4784184EF8D69052273F65D982918E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_3AFF8F71BBD60FD5C0FC3F65D9828AF1" xlink:to="loc_us-gaap_AccruedIncomeReceivableMember_2B4784184EF8D69052273F65D982918E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_A842C7908890E4815BDA3F65D983FFAB" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_A842C7908890E4815BDA3F65D983FFAB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_2E0E959BBEAED31EFAEB3F65D98320D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_A842C7908890E4815BDA3F65D983FFAB" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_2E0E959BBEAED31EFAEB3F65D98320D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SalesRevenueNetMember" xlink:label="loc_us-gaap_SalesRevenueNetMember_8DFBFA7A01666044975F3F65D983F768" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_2E0E959BBEAED31EFAEB3F65D98320D6" xlink:to="loc_us-gaap_SalesRevenueNetMember_8DFBFA7A01666044975F3F65D983F768" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsLineItems" xlink:label="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_14BFD13C30F3C32345A93F65D97B780F" xlink:to="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NumberOfOperatingSegments" xlink:label="loc_us-gaap_NumberOfOperatingSegments_01D6381C33A6B2AE18833F65D9833715" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_NumberOfOperatingSegments_01D6381C33A6B2AE18833F65D9833715" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_NumberofProducts" xlink:label="loc_vcyt_NumberofProducts_B22C1118824F62CF65993F65D984797E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_NumberofProducts_B22C1118824F62CF65993F65D984797E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_A43926B5555AC08E4EB43F65D9841B88" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_A43926B5555AC08E4EB43F65D9841B88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SaleOfStockPricePerShare" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_650B35C25B69A3A342E33F65D9842320" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_650B35C25B69A3A342E33F65D9842320" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_A760DDB632F466CEE05D3F65D984D2A4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_A760DDB632F466CEE05D3F65D984D2A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsOfStockIssuanceCosts" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_0222CCF01A6D144464083F65D9840B9D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_0222CCF01A6D144464083F65D9840B9D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited" xlink:label="loc_vcyt_NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited_BB4FB89F6D5FD3B4C4D53F65D9859C93" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_NumberOfMajorFinancialInstitutionsWithWhichCashAndCashEquivalentsDeposited_BB4FB89F6D5FD3B4C4D53F65D9859C93" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedCashAndCashEquivalentsNoncurrent" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_BE918643610B774A95953F65D9857A6B" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsNoncurrent_BE918643610B774A95953F65D9857A6B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_593B19732042FAE23ABB3F65D98523AF" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_593B19732042FAE23ABB3F65D98523AF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableGross" xlink:label="loc_us-gaap_AccountsReceivableGross_D03CD6E335EB7EB913683F65D985E9C4" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_AccountsReceivableGross_D03CD6E335EB7EB913683F65D985E9C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaap_CostOfRevenue_507B0DA9B368A71403EE3F65D98532B3" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_CostOfRevenue_507B0DA9B368A71403EE3F65D98532B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskPercentage1" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_E2F192CB55D9FE00C4573F65D9850708" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_E2F192CB55D9FE00C4573F65D9850708" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_57A93BE74750E3F020D83F65D9860991" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_OperatingIncomeLoss_57A93BE74750E3F020D83F65D9860991" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_A1F1BFED46825B18AC5E3F65D986C256" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_A1F1BFED46825B18AC5E3F65D986C256" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractWithCustomerLiabilityRevenueRecognized" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_9F5FB70645461F04442A3F65D986BBF6" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityRevenueRecognized_9F5FB70645461F04442A3F65D986BBF6" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_NumberofTissueSampleDeliveries" xlink:label="loc_vcyt_NumberofTissueSampleDeliveries_4E74CB60E776AB43A1883F73DF42962E" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_NumberofTissueSampleDeliveries_4E74CB60E776AB43A1883F73DF42962E" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_TermContractAgreement" xlink:label="loc_vcyt_TermContractAgreement_EBBBD0B5A3FD790B57323F65D986A0A3" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_TermContractAgreement_EBBBD0B5A3FD790B57323F65D986A0A3" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_AutomaticRenewalPeriodContractAgreement" xlink:label="loc_vcyt_AutomaticRenewalPeriodContractAgreement_DEDF39D86F6AD124EA323F65D986D317" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_AutomaticRenewalPeriodContractAgreement_DEDF39D86F6AD124EA323F65D986D317" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_TerminationPeriodContractAgreement" xlink:label="loc_vcyt_TerminationPeriodContractAgreement_8134872C74FE2D8266A13F70A78B89FA" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_TerminationPeriodContractAgreement_8134872C74FE2D8266A13F70A78B89FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_51E01306DDAA4EA99C333F65D986E7BD" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_ContractWithCustomerLiability_51E01306DDAA4EA99C333F65D986E7BD" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_DevelopmentPrograms" xlink:label="loc_vcyt_DevelopmentPrograms_F26659AB0DD4928ACABB3F6CFDC5F267" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_DevelopmentPrograms_F26659AB0DD4928ACABB3F6CFDC5F267" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ContractAgreementConditionalAdditionalReceivable" xlink:label="loc_vcyt_ContractAgreementConditionalAdditionalReceivable_808BB5BF1DF110B1E1053F65D987DE7F" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_ContractAgreementConditionalAdditionalReceivable_808BB5BF1DF110B1E1053F65D987DE7F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ContractAgreementReceivableForServices" xlink:label="loc_vcyt_ContractAgreementReceivableForServices_57820FD3538E19359D1E3F65D987D36F" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_ContractAgreementReceivableForServices_57820FD3538E19359D1E3F65D987D36F" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ContractAgreementFeePercentageOfCashCollections" xlink:label="loc_vcyt_ContractAgreementFeePercentageOfCashCollections_89D201BF685C0964D6883F65D987F0AD" xlink:type="locator" />
    <link:presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_vcyt_ContractAgreementFeePercentageOfCashCollections_89D201BF685C0964D6883F65D987F0AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_2F7A9A5BA4C3E07C6E8D3F65D9876762" xlink:type="locator" />
    <link:presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_2F7A9A5BA4C3E07C6E8D3F65D9876762" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_7DD743B1E225F019FEC63F65D988263F" xlink:type="locator" />
    <link:presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_7DD743B1E225F019FEC63F65D988263F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="loc_us-gaap_OperatingLeaseLiability_0398A9F8F25B324A0DFE3F65D988CC29" xlink:type="locator" />
    <link:presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_OperatingLeaseLiability_0398A9F8F25B324A0DFE3F65D988CC29" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeaseRightOfUseAsset" xlink:label="loc_us-gaap_FinanceLeaseRightOfUseAsset_6A6CA4665FEFF650176D3F65D9883331" xlink:type="locator" />
    <link:presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_FinanceLeaseRightOfUseAsset_6A6CA4665FEFF650176D3F65D9883331" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FinanceLeaseLiability" xlink:label="loc_us-gaap_FinanceLeaseLiability_4CF879E85A5E0FB7E9803F65D9884232" xlink:type="locator" />
    <link:presentationArc order="29" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_BC2A2EA16ABF3090AA483F65D9831300" xlink:to="loc_us-gaap_FinanceLeaseLiability_4CF879E85A5E0FB7E9803F65D9884232" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_08ACEAAF4D92155004DD1B3B402C08A3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_3A34F777FDAA99925B291B3B402C8B6B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_08ACEAAF4D92155004DD1B3B402C08A3" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_3A34F777FDAA99925B291B3B402C8B6B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="loc_us-gaap_UseOfEstimates_83BCC763436B1D7F2F9C1B3B402C3656" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_08ACEAAF4D92155004DD1B3B402C08A3" xlink:to="loc_us-gaap_UseOfEstimates_83BCC763436B1D7F2F9C1B3B402C3656" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ConcentrationsOfCreditAndOtherRisksAndUncertaintiesPolicyTextBlock" xlink:label="loc_vcyt_ConcentrationsOfCreditAndOtherRisksAndUncertaintiesPolicyTextBlock_1204109895AAEFA7EB551B3B402DE326" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_08ACEAAF4D92155004DD1B3B402C08A3" xlink:to="loc_vcyt_ConcentrationsOfCreditAndOtherRisksAndUncertaintiesPolicyTextBlock_1204109895AAEFA7EB551B3B402DE326" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy" xlink:label="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_E9A7BA7DA62F4591B8371B3B402D1AAB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_08ACEAAF4D92155004DD1B3B402C08A3" xlink:to="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_E9A7BA7DA62F4591B8371B3B402D1AAB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_3521AF5E803A7C06357F1B3B402DCF3C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_08ACEAAF4D92155004DD1B3B402C08A3" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_3521AF5E803A7C06357F1B3B402DCF3C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_8D45D237C87BAA163BB11B3B402D77FA" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_08ACEAAF4D92155004DD1B3B402C08A3" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_8D45D237C87BAA163BB11B3B402D77FA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/OrganizationAndDescriptionOfBusinessTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_417B6CC1E452FDAAB9621B3B40283A8D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock" xlink:label="loc_us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock_09EC824D4BCAB0E31B141B3B4029A22E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_417B6CC1E452FDAAB9621B3B40283A8D" xlink:to="loc_us-gaap_SchedulesOfConcentrationOfRiskByRiskFactorTextBlock_09EC824D4BCAB0E31B141B3B4029A22E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockholdersEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_7B5DF2D20523F923FDBD1B3B3F0D9690" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_BB19BCBDE9F7959ED4FC1B3B3F0D682E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_7B5DF2D20523F923FDBD1B3B3F0D9690" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_BB19BCBDE9F7959ED4FC1B3B3F0D682E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockholdersEquityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_91CB9511C25FD8DB8E1B1B3B3EF64A04" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfStockByClassTable" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_50BADDC9CEA3B8A0E5521B3B3EF6C9EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_91CB9511C25FD8DB8E1B1B3B3EF64A04" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_50BADDC9CEA3B8A0E5521B3B3EF6C9EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_6CE6623076CC40D25AA11B3B3EF67ACE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_50BADDC9CEA3B8A0E5521B3B3EF6C9EA" xlink:to="loc_us-gaap_AwardTypeAxis_6CE6623076CC40D25AA11B3B3EF67ACE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_D6952C7FBCE0382F8FAF1B3B3EF6C884" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_6CE6623076CC40D25AA11B3B3EF67ACE" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_D6952C7FBCE0382F8FAF1B3B3EF6C884" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_EmployeeAndNonEmployeeStockOptionMember" xlink:label="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_E2C7FDB2B3B112E8C30E1B3B3EF7CB0D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_D6952C7FBCE0382F8FAF1B3B3EF6C884" xlink:to="loc_vcyt_EmployeeAndNonEmployeeStockOptionMember_E2C7FDB2B3B112E8C30E1B3B3EF7CB0D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeStockMember" xlink:label="loc_us-gaap_EmployeeStockMember_9C2FFF8B7A6AE478CCFE1B3B3EF768C1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_D6952C7FBCE0382F8FAF1B3B3EF6C884" xlink:to="loc_us-gaap_EmployeeStockMember_9C2FFF8B7A6AE478CCFE1B3B3EF768C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ClassOfStockLineItems" xlink:label="loc_us-gaap_ClassOfStockLineItems_7F45809CBEA0BC0257811B3B3EFC509A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_50BADDC9CEA3B8A0E5521B3B3EF6C9EA" xlink:to="loc_us-gaap_ClassOfStockLineItems_7F45809CBEA0BC0257811B3B3EFC509A" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_CommonStockAbstract" xlink:label="loc_vcyt_CommonStockAbstract_B30CD89940E036F0A9701B3B3EFC3D79" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_7F45809CBEA0BC0257811B3B3EFC509A" xlink:to="loc_vcyt_CommonStockAbstract_B30CD89940E036F0A9701B3B3EFC3D79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_B0B5A5E9D44F4BDCDE721B3B3EFD276E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_B30CD89940E036F0A9701B3B3EFC3D79" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_B0B5A5E9D44F4BDCDE721B3B3EFD276E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_26E78724BE881E0DF2ED1B3B3EFD8644" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_B30CD89940E036F0A9701B3B3EFC3D79" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_26E78724BE881E0DF2ED1B3B3EFD8644" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_E24EB1BFF4CB1306A4381B3B3EFDF1B7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_CommonStockAbstract_B30CD89940E036F0A9701B3B3EFC3D79" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_E24EB1BFF4CB1306A4381B3B3EFDF1B7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/StockholdersEquityTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_BCCB53E0CCC399C46B3C1B3B3F056BD8" xlink:type="locator" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock" xlink:label="loc_vcyt_ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock_8B246C795B0C2D7E45931B3B3F05B2E7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_BCCB53E0CCC399C46B3C1B3B3F056BD8" xlink:to="loc_vcyt_ScheduleOfCommonStockCapitalSharesReservedForFutureIssuanceTableTextBlock_8B246C795B0C2D7E45931B3B3F05B2E7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ThyroidCytopathologyPartners" xlink:type="extended">
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ServicesAgreementAbstract" xlink:label="loc_vcyt_ServicesAgreementAbstract_B27E993A131524A3EE921B3B3EE7717B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermContractsOrProgramsDisclosureTextBlock" xlink:label="loc_us-gaap_LongTermContractsOrProgramsDisclosureTextBlock_51C74E24763164CDCEC41B3B3EE87A98" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ServicesAgreementAbstract_B27E993A131524A3EE921B3B3EE7717B" xlink:to="loc_us-gaap_LongTermContractsOrProgramsDisclosureTextBlock_51C74E24763164CDCEC41B3B3EE87A98" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.veracyte.com/role/ThyroidCytopathologyPartnersDetails" xlink:type="extended">
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_ServicesAgreementAbstract" xlink:label="loc_vcyt_ServicesAgreementAbstract_C5E05759AFD2B4208B531B3B3EDE572A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfVariableInterestEntitiesTable" xlink:label="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_833A3E41C0E6985013181B3B3EDE880E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_vcyt_ServicesAgreementAbstract_C5E05759AFD2B4208B531B3B3EDE572A" xlink:to="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_833A3E41C0E6985013181B3B3EDE880E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis" xlink:label="loc_us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis_85899CFA29EFAFA440261B3B3EDEAECE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_833A3E41C0E6985013181B3B3EDE880E" xlink:to="loc_us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis_85899CFA29EFAFA440261B3B3EDEAECE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ClassificationOfVariableInterestEntityDomain" xlink:label="loc_us-gaap_ClassificationOfVariableInterestEntityDomain_AE2440542788D3CF35571B3B3EDE76E9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntitiesByClassificationOfEntityAxis_85899CFA29EFAFA440261B3B3EDEAECE" xlink:to="loc_us-gaap_ClassificationOfVariableInterestEntityDomain_AE2440542788D3CF35571B3B3EDE76E9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember" xlink:label="loc_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember_C8DA71F7B230D7539A111B3B3EDF553F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassificationOfVariableInterestEntityDomain_AE2440542788D3CF35571B3B3EDE76E9" xlink:to="loc_us-gaap_VariableInterestEntityNotPrimaryBeneficiaryMember_C8DA71F7B230D7539A111B3B3EDF553F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VariableInterestEntityLineItems" xlink:label="loc_us-gaap_VariableInterestEntityLineItems_513AEE8A5A6B5ADF70651B3B3EDFF65D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_833A3E41C0E6985013181B3B3EDE880E" xlink:to="loc_us-gaap_VariableInterestEntityLineItems_513AEE8A5A6B5ADF70651B3B3EDFF65D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_AgreementTermsNonRenewalNoticePeriod" xlink:label="loc_vcyt_AgreementTermsNonRenewalNoticePeriod_4A193544C25F203C05EB1B3B3EDF5A0D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_513AEE8A5A6B5ADF70651B3B3EDFF65D" xlink:to="loc_vcyt_AgreementTermsNonRenewalNoticePeriod_4A193544C25F203C05EB1B3B3EDF5A0D" xlink:type="arc" />
    <link:loc xlink:href="vcyt-20190630.xsd#vcyt_OtherIncomeRentReimbursement" xlink:label="loc_vcyt_OtherIncomeRentReimbursement_4804A06D5522B3BDFEA31B3B3EE0F2F4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" priority="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_513AEE8A5A6B5ADF70651B3B3EDFF65D" xlink:to="loc_vcyt_OtherIncomeRentReimbursement_4804A06D5522B3BDFEA31B3B3EE0F2F4" xlink:type="arc" />
  </link:presentationLink>
</link:linkbase>
